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Protein
Submitted name:

Double-stranded RNA-binding protein Staufen homolog 2

Gene

STAU2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Double-stranded RNA-binding protein Staufen homolog 2Imported
Gene namesi
Name:STAU2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000040341.17
HGNCiHGNC:11371 STAU2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000040341

PTM / Processingi

Proteomic databases

MaxQBiE5RFK1
PeptideAtlasiE5RFK1
PRIDEiE5RFK1

Expressioni

Gene expression databases

BgeeiENSG00000040341 Expressed in 221 organ(s), highest expression level in frontal cortex
ExpressionAtlasiE5RFK1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RFK1
SMRiE5RFK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 149DRBMInterPro annotationAdd BLAST87

Phylogenomic databases

eggNOGiKOG3732 Eukaryota
ENOG410XSCK LUCA
GeneTreeiENSGT00900000140998

Family and domain databases

CDDicd00048 DSRM, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
PfamiView protein in Pfam
PF00035 dsrm, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

E5RFK1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLQINQMFSV QLSLGEQTWE SEGSSIKKAQ QAVANKALTE STLPKPVQKP
60 70 80 90 100
PKSNVNNNPG SITPTVELNG LAMKRGEPAI YRPLDPKPFP NYRANYNFRG
110 120 130 140 150
MYNQRYHCPV PKIFYVQLTV GNNEFFGEGK TRQAARHNAA MKALQALQNE
160 170 180 190 200
PIPERSPQNG ESGKDVDDDK DANKSEISLV FEIALKRNMP VSFEVIKESG

PPHM
Length:204
Mass (Da):22,799
Last modified:February 8, 2011 - v1
Checksum:iEA82348E61269918
GO

Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NUL3STAU2_HUMAN
Double-stranded RNA-binding protein...
STAU2
570Annotation score:
E9PH62E9PH62_HUMAN
Double-stranded RNA-binding protein...
STAU2
538Annotation score:
A0A0A0MTC4A0A0A0MTC4_HUMAN
Double-stranded RNA-binding protein...
STAU2
398Annotation score:
A0A0A0MTC6A0A0A0MTC6_HUMAN
Double-stranded RNA-binding protein...
STAU2
504Annotation score:
A0A0A0MTD1A0A0A0MTD1_HUMAN
Double-stranded RNA-binding protein...
STAU2
473Annotation score:
E5RJN7E5RJN7_HUMAN
Double-stranded RNA-binding protein...
STAU2
320Annotation score:
G5EA18G5EA18_HUMAN
Double-stranded RNA-binding protein...
STAU2
291Annotation score:
F8VPI7F8VPI7_HUMAN
Double-stranded RNA-binding protein...
STAU2
479Annotation score:
E5RJ67E5RJ67_HUMAN
Double-stranded RNA-binding protein...
STAU2
135Annotation score:
E7EVI1E7EVI1_HUMAN
Double-stranded RNA-binding protein...
STAU2
390Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei204Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018620 Genomic DNA No translation available.
AC027018 Genomic DNA No translation available.
AC100784 Genomic DNA No translation available.
KF458781 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000521447; ENSP00000428829; ENSG00000040341
UCSCiuc064nsk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018620 Genomic DNA No translation available.
AC027018 Genomic DNA No translation available.
AC100784 Genomic DNA No translation available.
KF458781 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE5RFK1
SMRiE5RFK1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE5RFK1
PeptideAtlasiE5RFK1
PRIDEiE5RFK1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000521447; ENSP00000428829; ENSG00000040341
UCSCiuc064nsk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000040341.17
HGNCiHGNC:11371 STAU2
OpenTargetsiENSG00000040341
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3732 Eukaryota
ENOG410XSCK LUCA
GeneTreeiENSGT00900000140998

Miscellaneous databases

ChiTaRSiSTAU2 human

Gene expression databases

BgeeiENSG00000040341 Expressed in 221 organ(s), highest expression level in frontal cortex
ExpressionAtlasiE5RFK1 baseline and differential

Family and domain databases

CDDicd00048 DSRM, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
PfamiView protein in Pfam
PF00035 dsrm, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RFK1_HUMAN
AccessioniPrimary (citable) accession number: E5RFK1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 12, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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