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Protein

DNA polymerase

Gene

GSOID_T00017937001

Organism
Oikopleura dioica (Tunicate)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation, DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase
Biological processDNA replicationUniRule annotation
Ligand4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
ORF Names:GSOID_T00017937001Imported, GSOID_T00021634001Imported
OrganismiOikopleura dioica (Tunicate)Imported
Taxonomic identifieri34765 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAppendiculariaOikopleuridaeOikopleura
Proteomesi
  • UP000001307 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 75DNA_pol_alpha_NInterPro annotationAdd BLAST60
Domaini334 – 660DNA_pol_B_exo1InterPro annotationAdd BLAST327
Domaini732 – 1159DNA_pol_BInterPro annotationAdd BLAST428
Domaini1246 – 1379zf-DNA_PolInterPro annotationAdd BLAST134

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili856 – 876Sequence analysisAdd BLAST21
Coiled coili1183 – 1205Sequence analysisAdd BLAST23
Coiled coili1324 – 1344Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerUniRule annotation

Family and domain databases

Gene3Di1.10.3200.20, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 2 hits
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR017964 DNA-dir_DNA_pol_B_CS
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR024647 DNA_pol_a_cat_su_N
IPR023211 DNA_pol_palm_dom_sf
IPR038256 Pol_alpha_znc_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR015088 Znf_DNA-dir_DNA_pol_B_alpha
PfamiView protein in Pfam
PF12254 DNA_pol_alpha_N, 1 hit
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08996 zf-DNA_Pol, 1 hit
PRINTSiPR00106 DNAPOLB
SMARTiView protein in SMART
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS00116 DNA_POLYMERASE_B, 1 hit

Sequencei

Sequence statusi: Complete.

E4XQI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERSRRNRTQ DKRSEALAKL KRGGGIHDYE VDEVQNVYEE VDEGTYQEMR
60 70 80 90 100
DQRASDFVVG ADADDWMDDG RDVFDDDDEP FQEDAKTKKQ KKKMAKFASG
110 120 130 140 150
SGNIAAMILK QAKNSKTKTK AKDIKMHDDD DLDAIMNEID DGNVSMKVTP
160 170 180 190 200
RLKKSKKSKK PQAPAITFNS SPEKSSKKRV LQQRVQNPTK RPKLDKNVFK
210 220 230 240 250
REAEAKQEYI SDNDDELPEP GDVFGDNDFD EEMSEDENRI PKKEPSSTEI
260 270 280 290 300
SSKLQNISME EEKSVINHVK EEPDSQIDWN ATKTCVEFDK EEDIQYPVDE
310 320 330 340 350
NCLNLYWLDA YETQYNKSGK LYLTGRANVA GELKSCCLII SNIPHVVYIL
360 370 380 390 400
PRENSDTGDV YEEIGEWMDK NKVDSWKAKP MKKKNFFGGA GVPPEAEYLR
410 420 430 440 450
VEYGPKNPLM SSTMKGAHFS HVFNVNQPLF EFFALERNIM GPCWLSISSY
460 470 480 490 500
SPVSGGAISW CSVEYDCTDY RAVQVHPDSE KMHEPQLTMV SLSFKTIPLK
510 520 530 540 550
KTNELAAFTL VVNKNFRLSS TKKVPEHDYI MTALSKPATM TLPYDWNGEM
560 570 580 590 600
GGNNEKVESC LGEKHLLNIF LKELRQIDPD IILGHDLLDF GLEYILQRMK
610 620 630 640 650
VHSVNGWSRL GRIKRKDMPR MAAQIGLARA GHDACNGRLV ADTKTSAMEL
660 670 680 690 700
VKMRDYNLTS LCEEQIPEQL SGLKPHFLYA CKNRKEYLPE HIVEAFGSSN
710 720 730 740 750
TLRMLLQENI NDCFRNMLIS SNIQSLPLAV QITNICGNIL SRTLSRGRAE
760 770 780 790 800
RNAYLLLHAF HKKDHLPPPP YKKKTVEDGD KKGPKFAGGM VLEPKKGLYT
810 820 830 840 850
NYILLLDFNS LYPSIIQEYN ICFTTTAMQA PPGEDISTWL PDLPKTMEEG
860 870 880 890 900
ILPFEIKKLV NRRKEVKKLI KNEKNADELA RLNIRQLGLK LTANSMYGCL
910 920 930 940 950
GFTASRFCAQ PLAALVTAKG REILEATKVF VEKMNLEVVY GDTDSIMINS
960 970 980 990 1000
NSTNISEVMK LGNLVKKEVN KHYRLLEIDI DGAYKSMLLL KKKKYAAIDQ
1010 1020 1030 1040 1050
NGKEEFKGLD IVRRDWSEIA RNEGRTILKL LLHEQDEEEG VRKIHEHLEM
1060 1070 1080 1090 1100
IGTKLENKEY RTVDYRIQKA LTKAPEQYPK SGDGQPHVKV ALRMNKKQPG
1110 1120 1130 1140 1150
KFKAGDTVPY IICCGDEKLK AADRAFHPSE VAREKKEIDI DYYLRSQLVP
1160 1170 1180 1190 1200
VFGRLLDPIE ATDEQQIATR LGMDPSAFKS RAATRARAER EEEMARIASQ
1210 1220 1230 1240 1250
KEEEKLANCT PLEINIGEER LTLDLFVPPF SQNYGDGKAL REKMSQIECA
1260 1270 1280 1290 1300
LRKALKLQIK RVYDNWQICS CGYRTRFISP NYTSKGLFAC PSCEDDILKC
1310 1320 1330 1340 1350
EFSISDFYLQ LQFFQRIFDA DAWLKKMNSE IPKEKEQREM ALKEINRVNE
1360 1370 1380
DYAYYVGVKK IADEAMKRCN FGKVSLPSLW SSHFTTF
Length:1,387
Mass (Da):158,496
Last modified:February 8, 2011 - v1
Checksum:iF6A844B04160F48B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN653105 Genomic DNA Translation: CBY12070.1
FN654439 Genomic DNA Translation: CBY33695.1

Entry informationi

Entry nameiE4XQI4_OIKDI
AccessioniPrimary (citable) accession number: E4XQI4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: April 25, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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