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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Liberibacter solanacearum (strain CLso-ZC1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotationSAAS annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotationSAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationSAAS annotation, Transferase
Biological processCell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCLIB658172:G1GQI-663-MONOMER
UniPathwayi
UPA00219

Protein family/group databases

CAZyiGT28 Glycosyltransferase Family 28

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationSAAS annotation (EC:2.4.1.227UniRule annotationSAAS annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotation
Ordered Locus Names:CKC_03355Imported
OrganismiLiberibacter solanacearum (strain CLso-ZC1)Imported
Taxonomic identifieri658172 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeLiberibacter
Proteomesi
  • UP000007038 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalSequence analysisAdd BLAST20
Transmembranei77 – 96HelicalSequence analysisAdd BLAST20
Transmembranei103 – 122HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Interactioni

Protein-protein interaction databases

STRINGi658172.CKC_03355

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 148Glyco_transf_28InterPro annotationAdd BLAST135
Domaini195 – 357Glyco_tran_28_CInterPro annotationAdd BLAST163

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
HOGENOMiHOG000218321
KOiK02563
OrthoDBiPOG091H02FX

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit

Sequencei

Sequence statusi: Complete.

E4UB29-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKYDYNLAK KNAILLVAGG TGGHVFPAVA LSHELKKRGY PVYLAIDHRA
60 70 80 90 100
QCFVEDFSPE EIYVVPSSQI RLSNPVVIFR SLMALWKGFI VSLRLIRKLK
110 120 130 140 150
PKVIVGFGGY HTLSPMLAGI ILQIPSMIHE QNAVMGRANR LLSWGVKVIA
160 170 180 190 200
GGLLSSKKGL LSHKIIITGN PVRNAFIKMA NIPYQASYSN QPFRLLIFGG
210 220 230 240 250
SQGAKVFSDI IPKSIALIPK EQRQRLIITQ QVKEDEKEIV QKIYDDLGLK
260 270 280 290 300
AHISSFFKDI EKYIFEANLL ICRSGALTVS EIAVIGRPVI LIPYPHSINQ
310 320 330 340 350
DQLHNAWFLQ EGGGAKVITQ NFLSPERLAN EISSAMKNPE SLVQMAKQVS
360 370 380
MKGKYKAVLL LSDLVEQLAR KESVSSLGRK YTC
Length:383
Mass (Da):42,582
Last modified:February 8, 2011 - v1
Checksum:i597CEE5A9A6AC268
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002371 Genomic DNA Translation: ADR52420.1
RefSeqiWP_013462076.1, NC_014774.1

Genome annotation databases

EnsemblBacteriaiADR52420; ADR52420; CKC_03355
KEGGilso:CKC_03355

Similar proteinsi

Entry informationi

Entry nameiE4UB29_LIBSC
AccessioniPrimary (citable) accession number: E4UB29
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: February 28, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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