UniProtKB - E3WH18 (E3WH18_HUMAN)
Protein
Submitted name:
Estrogen receptor alpha
Gene
ESR1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
- estrogen receptor activity Source: InterPro
- steroid binding Source: InterPro
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | ReceptorImported |
Names & Taxonomyi
Protein namesi | Submitted name: Estrogen receptor alphaImported |
Gene namesi | Name:ESR1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- nucleus Source: InterPro
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 142 – 174 | DisorderedSequence analysisAdd BLAST | 33 |
Family and domain databases
InterProi | View protein in InterPro IPR001292, Oestr_rcpt |
Pfami | View protein in Pfam PF02159, Oest_recep, 1 hit |
PRINTSi | PR00543, OESTROGENR |
i Sequence
Sequence statusi: Fragment.
E3WH18-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLHTKASGM ALLHQIQGNE LEPLNRPQLK IPLERPLGEV YLDSSKPAVY
60 70 80 90 100
NYPEGAAYEF NAAAAANAQV YGQTGLPYGP GSEAAAFGSN GLGGFPPLNS
110 120 130 140 150
VSPSPLMLLH PPPQLSPFLQ PHGQQVPYYL ENEPSGYTVR EAGPPAFYRP
160 170 180 190
NSDNRRQGGR ERLASTNDKG SMAMESAKET RYCAVCNDYA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 190 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB588629 mRNA Translation: BAJ41265.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB588629 mRNA Translation: BAJ41265.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | E3WH18 |
Miscellaneous databases
ChiTaRSi | ESR1, human |
Family and domain databases
InterProi | View protein in InterPro IPR001292, Oestr_rcpt |
Pfami | View protein in Pfam PF02159, Oest_recep, 1 hit |
PRINTSi | PR00543, OESTROGENR |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E3WH18_HUMAN | |
Accessioni | E3WH18Primary (citable) accession number: E3WH18 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 8, 2011 |
Last sequence update: | February 8, 2011 | |
Last modified: | August 12, 2020 | |
This is version 39 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |