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Entry version 36 (08 May 2019)
Sequence version 1 (11 Jan 2011)
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Protein
Submitted name:

Two-partner secreted adhesin EtpA

Gene

etpA

Organism
Escherichia coli O78:H11 (strain H10407 / ETEC)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Two-partner secreted adhesin EtpAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:etpAImported
Ordered Locus Names:ETEC_p948_0110Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid p948Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli O78:H11 (strain H10407 / ETEC)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri316401 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006877 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Plasmid p948

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini65 – 178Haemagg_actInterPro annotationAdd BLAST114

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
NITMQGT

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.160.20.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024973 ESPR
IPR008638 Filamn_hemagglutn_N
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13018 ESPR, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00912 Haemagg_act, 1 hit
SM00710 PbH1, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51126 SSF51126, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01901 adhes_NPXG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E3PP99-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNRIYKLKFD KRRNELVVVS EITTGVGNAK ATGSVEGEKS PRRGVRAMAL
60 70 80 90 100
SLLSGMMIMA HPAMSANLPT GGQIVAGSGS IQTPSGNQMN IHQNSQNMVA
110 120 130 140 150
NWNSFDIGKG NTVQFDQPSS SAVALNRVVG GGESQIMGNL KANGQVFLVN
160 170 180 190 200
PNGVLFGEGA SVSTSGFVAS TRDIKNDDFM NRRYTFSGGQ KAGAAIVNQG
210 220 230 240 250
ELTTNAGGYI VLAADRVSNS GTIRTPGGKT VLAASERITL QLDNGGLMSV
260 270 280 290 300
QVTGDVVNAL VENRGLVSAR DGQVYLTALG RGMLMNTVLN VSGVVEASGM
310 320 330 340 350
HRQDGNIVLD GGDSGVVHLS GTLQADNASG QGGKVVVQGK NILLDKGSNI
360 370 380 390 400
TATGGQGGGE VYVGGGWQGK DSNIRNADKV VMQGGARIDV SATQQGNGGT
410 420 430 440 450
AVLWSDSYTN FHGQISAKGG ETGGNGGRVE TSSHGNLQAF GTVSASAKKG
460 470 480 490 500
KAGNWLLDSA DITIVNGSNV SKTETTQSPP HTQFAPTAAG SAVSNTSINN
510 520 530 540 550
RLNNGTSVTI LTHRTRTGTA QGGNITVNAA INKSNGSDVN LTLQAGGNIT
560 570 580 590 600
VNNSITSTEG KLNVNLSGAR TSNGSITISN NANITTNGGD ITVGTTNTSN
610 620 630 640 650
RVNISINNTT LNASNGNIQL TGTGTDSGIL FAGNNRLTAS NIALTGNSTS
660 670 680 690 700
GNAINLTGTA TLNATNNITL TGSSTSGNAI NLKGNNTLTA SNITLTGEST
710 720 730 740 750
SGNAINLTDT TGTTTLNATN NITMQGTRVQ IKHSNITAGN FALNATVAGS
760 770 780 790 800
EISNTTLTAT NNINLAAKTN SASSGVYLKD ARITSTNGSI TANGTATANG
810 820 830 840 850
KATHLDGNVT LNASNGRIKL TGNGHGSASG ILFAGNNRLT ASNIALTGNS
860 870 880 890 900
TSGNAINLTG TATLNATNDI TLTGSSTSGN AINLTGTATL NATNNITLTG
910 920 930 940 950
SSTSGNAINL KGNNTLTASN ITLTGESTSG NAINLTDTTG TTTLNATNNI
960 970 980 990 1000
TMQGTRVQIK HSNITAGNFA LNATVAGSEI SNTTLTATNN INLAAKTNSA
1010 1020 1030 1040 1050
SSGVYLKDAR ITSTNGSITA NGTATANGKA THLDGNVTLN ASNGRIKLTG
1060 1070 1080 1090 1100
NGHGSASGIL FAGNNRLTAS NIALTGNSTS GNAINLTGTA TLNATNDITL
1110 1120 1130 1140 1150
TGSSTSGNAI NLTGTATLNA TNNITLTGSS TSGNAINLKG NNTLTASNIT
1160 1170 1180 1190 1200
LTGESTSGNA INLTDTTGTT TLNATNNITM QGTRVQIKHS NITAGNFALN
1210 1220 1230 1240 1250
ATVAGSEISN TTLTATNNIN LAAKTNSASS GVYLKDARIT STNGSITANG
1260 1270 1280 1290 1300
TATANGKATH LDGNVTLNAS NGRIKLTGNG HGSASGILFA GNNRLTASNI
1310 1320 1330 1340 1350
ALTGNSTSGN AINLTGTATL NATNDITLTG SSTSGNAINL TGTATLNATN
1360 1370 1380 1390 1400
NITLTGSSTS GNAINLKGNN TLTASNITLT GESTSGNAIN LTDTTGTTTL
1410 1420 1430 1440 1450
NATNNITMQG TRVQIKHSNI TAGNFALNAT VAGSEISNTT LTATNNINLA
1460 1470 1480 1490 1500
AKTNSASSGV YLKDARITST NGSITANGTA PANDNATYLD GNVTLNASNG
1510 1520 1530
SIKLTGNGNG STSGILFAGN NTLTASNITL TGNSEVYWQ
Length:1,539
Mass (Da):154,464
Last modified:January 11, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3BE9ACF0A78B41C0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FN649418 Genomic DNA Translation: CBJ04458.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CBJ04458; CBJ04458; ETEC_p948_0110

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
elh:ETEC_p948_0110

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN649418 Genomic DNA Translation: CBJ04458.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBJ04458; CBJ04458; ETEC_p948_0110
KEGGielh:ETEC_p948_0110

Phylogenomic databases

OMAiNITMQGT

Family and domain databases

Gene3Di2.160.20.10, 1 hit
InterProiView protein in InterPro
IPR024973 ESPR
IPR008638 Filamn_hemagglutn_N
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
PfamiView protein in Pfam
PF13018 ESPR, 1 hit
SMARTiView protein in SMART
SM00912 Haemagg_act, 1 hit
SM00710 PbH1, 12 hits
SUPFAMiSSF51126 SSF51126, 1 hit
TIGRFAMsiTIGR01901 adhes_NPXG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE3PP99_ECOH1
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E3PP99
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: May 8, 2019
This is version 36 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteomeImported, PlasmidImported
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