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Entry version 44 (02 Jun 2021)
Sequence version 1 (11 Jan 2011)
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Protein

Putative lipoprotein YghJ

Gene

yghJ

Organism
Escherichia coli O78:H11 (strain H10407 / ETEC)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a substrate of the type II secretion system beta (T2SS-beta).

1 Publication

Miscellaneous

Encoded in a type II secretion system (T2SS-beta); this strain encodes 2 T2SS but only this one (beta) is expressed under standard laboratory conditions.1 Publication

Protein family/group databases

MEROPS protease database

More...
MEROPSi
M98.001

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative lipoprotein YghJ
Alternative name(s):
Putative lipoprotein AcfD homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yghJ
Ordered Locus Names:ETEC_3241
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli O78:H11 (strain H10407 / ETEC)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri316401 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006877 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No effect on assembly or function of T2SS-beta.1 Publication

Miscellaneous databases

Pathogen-Host Interaction database

More...
PHI-basei
PHI:7003

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23PROSITE-ProRule annotationAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000040530524 – 1519Putative lipoprotein YghJAdd BLAST1496

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi24N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi24S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1080 – 1380Peptidase M60PROSITE-ProRule annotationAdd BLAST301

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni22 – 107DisorderedSequence analysisAdd BLAST86
Regioni226 – 247DisorderedSequence analysisAdd BLAST22
Regioni1497 – 1519DisorderedSequence analysisAdd BLAST23

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi26 – 40Polar residuesSequence analysisAdd BLAST15
Compositional biasi49 – 87Pro residuesSequence analysisAdd BLAST39
Compositional biasi93 – 107Polar residuesSequence analysisAdd BLAST15
Compositional biasi227 – 247Polar residuesSequence analysisAdd BLAST21
Compositional biasi1505 – 1519Polar residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

To V.cholerae AcfD (VC_0845).Curated

Keywords - Domaini

Signal

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006312_0_0_6

Identification of Orthologs from Complete Genome Data

More...
OMAi
VMGNARY

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.390.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025385, DUF4092
IPR035423, M60-like_N
IPR042279, Pep_M60_3
IPR031161, Peptidase_M60_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13322, DUF4092, 1 hit
PF17291, M60-like_N, 1 hit
PF13402, Peptidase_M60, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01276, M60-like, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51723, PEPTIDASE_M60, 1 hit
PS51257, PROKAR_LIPOPROTEIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

E3PJ90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKKFKYKKS LLAAILSATL LAGCDGGGSG SSSDTPPVDS GTGSLPEVKP
60 70 80 90 100
DPTPNPEPTP EPTPDPEPTP EPIPDPEPTP EPEPEPVPTK TGYLTLGGSQ
110 120 130 140 150
RVTGATCNGE SSDGFTFKPG EDVTCVAGNT TIATFNTQSE AARSLRAVEK
160 170 180 190 200
VSFSLEDAQE LAGSDDKKSN AVSLVTSSNS CPANTEQVCL TFSSVIESKR
210 220 230 240 250
FDSLYKQIDL APEEFKKLVN EEVENNAATD KAPSTHTSPV VPVTTPGTKP
260 270 280 290 300
DLNASFVSAN AEQFYQYQPT EIILSEGRLV DSQGYGVAGV NYYTNSGRGV
310 320 330 340 350
TGENGEFSFS WGEAISFGID TFELGSVRGN KSTIALTELG DEVRGANIDQ
360 370 380 390 400
LIHRYSTTGQ NNTRVVPDDV RKVFAEYPNV INEIINLSLS NGATLGEGEQ
410 420 430 440 450
VVNLPNEFIE QFNTGQAKEI DTAICAKTDG CNEARWFSLT TRNVNDGQIQ
460 470 480 490 500
GVINKLWGVD TNYKSVSKFH VFHDSTNFYG STGNARGQAV VNISNAAFPI
510 520 530 540 550
LMARNDKNYW LAFGEKRAWD KNELAYITEA PSIVRPENVT RETASFNLPF
560 570 580 590 600
ISLGQVGDGK LMVIGNPHYN SILRCPNGYS WNGGVNKDGQ CTLNSDPDDM
610 620 630 640 650
KNFMENVLRY LSNDRWLPDA KSSMTVGTNL ETVYFKKHGQ VLGNSAPFAF
660 670 680 690 700
HKDFTGITVK PMTSYGNLNP DEVPLLILNG FEYVTQWGSD PYSIPLRADT
710 720 730 740 750
SKPKLTQQDV TDLIAYMNKG GSVLIMENVM SNLKEESASG FVRLLDAAGL
760 770 780 790 800
SMALNKSVVN NDPQGYPDRV RQRRSTPIWV YERYPAVDGK PPYTIDDTTK
810 820 830 840 850
EVIWKYQQEN KPDDKPKLEV ASWQEEVEGK QVTQFAFIDE ADHKTPESLA
860 870 880 890 900
AAKQRILDAF PGLEVCKDSD YHYEVNCLEY RPGTDVPVTG GMYVPQYTQL
910 920 930 940 950
DLSADTAKAM LQAADLGTNI QRLYQHELYF RTNGRQGERL NSVDLERLYQ
960 970 980 990 1000
NMSVWLWNET KYRYEEGKED ELGFKTFTEF LNCYTNNAYV GTQCSAELKK
1010 1020 1030 1040 1050
SLIDNKMIYG EESSKAGMMN PSYPLNYMEK PLTRLMLGRS WWDLNIKVDV
1060 1070 1080 1090 1100
EKYPGVVNTN GETVTQNINL YSAPTKWFAG NMQSTGLWAP AQQEVSIESK
1110 1120 1130 1140 1150
STVPVTVTVA LADDLTGREK HEVSLNRPPR VTKTYDLKAN DKVTFKVPYG
1160 1170 1180 1190 1200
GLIYIKGDSK EVQSADFTFT GVVKAPFYKD GKWQHDLNSP APLGELESAS
1210 1220 1230 1240 1250
FVYTTPKKNL NASNYTGGLE QFANDLDTFA SSMNDFYGRD SEDGKHRMFT
1260 1270 1280 1290 1300
YKNLPGHKHR FANDVQISIG DAHSGYPVMN SSFSPNSTTL PTTPLNDWLI
1310 1320 1330 1340 1350
WHEVGHNAAE TPLTVPGATE VANNVLALYM QDRYLGKMNR VADDITVAPE
1360 1370 1380 1390 1400
YLEESNGQAW ARGGAGDRLL MYAQLKEWAE KNFDIKKWYP DGTPLPEFYS
1410 1420 1430 1440 1450
EREGMKGWNL FQLMHRKARG DEVSNDKFGG KNYCAESNGN AADTLMLCAS
1460 1470 1480 1490 1500
WVAQTDLSEF FKKWNPGANA YQLPGASEMS FEGGVSQSAY NTLASLDLPK
1510
PEQGPETINQ VTEHKMSAE
Length:1,519
Mass (Da):168,014
Last modified:January 11, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i402DB4A166EE2165
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FN649414 Genomic DNA Translation: CBJ02741.1
AY056599 Genomic DNA Translation: AAL10688.1

NCBI Reference Sequences

More...
RefSeqi
WP_001034464.1, NC_017633.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CBJ02741; CBJ02741; ETEC_3241

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
elh:ETEC_3241

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN649414 Genomic DNA Translation: CBJ02741.1
AY056599 Genomic DNA Translation: AAL10688.1
RefSeqiWP_001034464.1, NC_017633.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

MEROPSiM98.001

Genome annotation databases

EnsemblBacteriaiCBJ02741; CBJ02741; ETEC_3241
KEGGielh:ETEC_3241

Phylogenomic databases

HOGENOMiCLU_006312_0_0_6
OMAiVMGNARY

Miscellaneous databases

PHI-baseiPHI:7003

Family and domain databases

Gene3Di1.10.390.30, 1 hit
InterProiView protein in InterPro
IPR025385, DUF4092
IPR035423, M60-like_N
IPR042279, Pep_M60_3
IPR031161, Peptidase_M60_dom
PfamiView protein in Pfam
PF13322, DUF4092, 1 hit
PF17291, M60-like_N, 1 hit
PF13402, Peptidase_M60, 1 hit
SMARTiView protein in SMART
SM01276, M60-like, 1 hit
PROSITEiView protein in PROSITE
PS51723, PEPTIDASE_M60, 1 hit
PS51257, PROKAR_LIPOPROTEIN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiACFD_ECOH1
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E3PJ90
Secondary accession number(s): Q2M9M2
, Q46837, Q46838, Q6BF58
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: January 11, 2011
Last modified: June 2, 2021
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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