Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Achromobacter xylosoxidans (strain A8)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotationSAAS annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotationSAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationSAAS annotationImported, Transferase
Biological processCell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAXYL762376:G1GOM-787-MONOMER
UniPathwayi
UPA00219

Protein family/group databases

CAZyiGT28 Glycosyltransferase Family 28

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationSAAS annotation (EC:2.4.1.227UniRule annotationSAAS annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotationImported
Ordered Locus Names:AXYL_00789Imported
OrganismiAchromobacter xylosoxidans (strain A8)Imported
Taxonomic identifieri762376 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeAchromobacter
Proteomesi
  • UP000006876 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi762376.AXYL_00789

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 144Glyco_transf_28InterPro annotationAdd BLAST138
Domaini184 – 341Glyco_tran_28_CInterPro annotationAdd BLAST158

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
HOGENOMiHOG000218321
KOiK02563
OMAiHQTKNAM
OrthoDBiPOG091H02FX

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit

Sequencei

Sequence statusi: Complete.

E3HGD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTASRTILIM AGGTGGHIMP GLAVADVLRE RGWRVLWLGN PEKMEGRLVP
60 70 80 90 100
PRGIELVPLR FQGVRGKGAS ALLKLPFLLL RAFGQAWSRL SDVRPDVVLG
110 120 130 140 150
MGGYVAFPGG VIAALRGTPL VVHEQNAVAG TANKWLARMA RRVLSGFPGV
160 170 180 190 200
LPKGEAMGNP VRADLCALPD PAARYAGRSG PLRVLIVGGS LGAQALNTTL
210 220 230 240 250
PQALARLPQE SRPMVVHQAG EQHLPALQQA YAQAGVEADC RAFIDDMAGA
260 270 280 290 300
MGDADLLICR AGAMTVSEVA AAGVAALFVP FPHAIDDHQT ANARFLSDAQ
310 320 330 340 350
AAWLQPQTGL TPEWLAQWLG QRSRQELQAV AERARAHARP EAAAHIADVC

EQAAGRSS
Length:358
Mass (Da):37,836
Last modified:January 11, 2011 - v1
Checksum:iF7082045F1E74D90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002287 Genomic DNA Translation: ADP14139.1
RefSeqiWP_013391528.1, NC_014640.1

Genome annotation databases

EnsemblBacteriaiADP14139; ADP14139; AXYL_00789
KEGGiaxy:AXYL_00789
PATRICifig|762376.5.peg.787

Similar proteinsi

Entry informationi

Entry nameiE3HGD9_ACHXA
AccessioniPrimary (citable) accession number: E3HGD9
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: February 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again