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Protein

50S ribosomal protein L5

Gene

rplE

Organism
Rothia dentocariosa (strain ATCC 17931 / CDC X599 / XDIA)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationImported, RNA-binding, rRNA-bindingUniRule annotation, tRNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L5UniRule annotation
Gene namesi
Name:rplEUniRule annotationImported
Ordered Locus Names:HMPREF0733_10289Imported
OrganismiRothia dentocariosa (strain ATCC 17931 / CDC X599 / XDIA)Imported
Taxonomic identifieri762948 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeRothia
Proteomesi
  • UP000000387 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Protein-protein interaction databases

STRINGi762948.HMPREF0733_10289

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 86Ribosomal_L5InterPro annotationAdd BLAST57
Domaini90 – 183Ribosomal_L5_CInterPro annotationAdd BLAST94

Sequence similaritiesi

Belongs to the universal ribosomal protein uL5 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW6 Bacteria
COG0094 LUCA
HOGENOMiHOG000231311
KOiK02931
OMAiEQVMFHE
OrthoDBiPOG091H007J

Family and domain databases

Gene3Di3.30.1440.10, 1 hit
HAMAPiMF_01333_B Ribosomal_L5_B, 1 hit
InterProiView protein in InterPro
IPR002132 Ribosomal_L5
IPR020930 Ribosomal_L5_bac-type
IPR031309 Ribosomal_L5_C
IPR020929 Ribosomal_L5_CS
IPR022803 Ribosomal_L5_dom_sf
IPR031310 Ribosomal_L5_N
PANTHERiPTHR11994 PTHR11994, 1 hit
PfamiView protein in Pfam
PF00281 Ribosomal_L5, 1 hit
PF00673 Ribosomal_L5_C, 1 hit
PIRSFiPIRSF002161 Ribosomal_L5, 1 hit
SUPFAMiSSF55282 SSF55282, 1 hit
PROSITEiView protein in PROSITE
PS00358 RIBOSOMAL_L5, 1 hit

Sequencei

Sequence statusi: Complete.

E3GZL2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSETKITPRF KTKYAEVVVP ALQEEFKYQN VMQTPKFVKV VVNMGVGEAA
60 70 80 90 100
RDAKLMDGAI RDLTAITGQK PVVTRAKKSI AQFKLREGMP IGAHVTLRGD
110 120 130 140 150
RMWEFLDRLV TLALPRIRDF RGLSDRQFDG NGNYTFGLTE QSMFHEIDQD
160 170 180
SIDRVRGMDI TVVTSAKTDD EGRAMLKALG FPFKTN
Length:186
Mass (Da):20,991
Last modified:January 11, 2011 - v1
Checksum:i2BC7B65B5A80D335
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002280 Genomic DNA Translation: ADP39747.1
RefSeqiWP_004005274.1, NC_014643.1

Genome annotation databases

EnsemblBacteriaiADP39747; ADP39747; HMPREF0733_10289
GeneIDi29743364
KEGGirdn:HMPREF0733_10289

Similar proteinsi

Entry informationi

Entry nameiE3GZL2_ROTDC
AccessioniPrimary (citable) accession number: E3GZL2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: March 28, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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