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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Bifidobacterium bifidum (strain S17)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei56NucleophileUniRule annotation1
Binding sitei125SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotation
Biological processtRNA processingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotationImported
Ordered Locus Names:BBIF_1475Imported
OrganismiBifidobacterium bifidum (strain S17)Imported
Taxonomic identifieri883062 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000006869 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini159 – 280PseudoU_synth_1InterPro annotationAdd BLAST122

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 1 hit
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit

Sequencei

Sequence statusi: Complete.

E3ERA5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRIDLAYDGG GFFGWAKQPT IRTVQGEIER VLHTITRVPV DDPAEPLRLT
60 70 80 90 100
VAGRTDTGVH ASHQVCHLDI GEETLSRCVG HMSVPPTVAL KHRLQRMLPA
110 120 130 140 150
DITIHDVTVA PSGFDARFSA LERTYVYRVA DRASEVDPRL RGFVLHLDAD
160 170 180 190 200
LDVVAMNEAA AMTIGLHDFG SFATPNPGGT TIREVKTAYW RRIPTRPLVV
210 220 230 240 250
DGMGERYRTP AAESDLLCFT IVADAFARNM VRSLVGGCIQ VGMGKRSTDW
260 270 280 290
FREKMAVPLR EGSTGPIAPQ GLTLEHVAYP ADDELAERAE RIRAKRTL
Length:298
Mass (Da):32,852
Last modified:January 11, 2011 - v1
Checksum:i813A0420E9A7A59E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002220 Genomic DNA Translation: ADO53680.1

Genome annotation databases

EnsemblBacteriaiADO53680; ADO53680; BBIF_1475
KEGGibbi:BBIF_1475

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002220 Genomic DNA Translation: ADO53680.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO53680; ADO53680; BBIF_1475
KEGGibbi:BBIF_1475

Phylogenomic databases

HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 1 hit
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE3ERA5_BIFBS
AccessioniPrimary (citable) accession number: E3ERA5
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: November 7, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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