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Entry version 43 (05 Jun 2019)
Sequence version 1 (11 Jan 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene

BBIF_1257

Organism
Bifidobacterium bifidum (strain S17)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BBIF883062:G1GOD-1309-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM51 Carbohydrate-Binding Module Family 51
GH110 Glycoside Hydrolase Family 110

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:BBIF_1257Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBifidobacterium bifidum (strain S17)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri883062 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006869 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1271 – 1295HelicalSequence analysisAdd BLAST25

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 37Sequence analysisAdd BLAST37
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500316909138 – 1303Sequence analysisAdd BLAST1266

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini958 – 1109NPCBMInterPro annotationAdd BLAST152

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1201 – 1276DisorderedSequence analysisAdd BLAST76

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1206 – 1226PolyampholyteSequence analysisAdd BLAST21
Compositional biasi1227 – 1241Pro-richSequence analysisAdd BLAST15

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000166201

Identification of Orthologs from Complete Genome Data

More...
OMAi
YISNDAQ

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.160.20.10, 2 hits
2.60.120.1060, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039448 Beta_helix
IPR003343 Big_2
IPR025883 Cadherin-like_b_sandwich
IPR008979 Galactose-bd-like_sf
IPR013222 Glyco_hyd_98_carb-bd
IPR008964 Invasin/intimin_cell_adhesion
IPR038637 NPCBM_sf
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13229 Beta_helix, 1 hit
PF02368 Big_2, 1 hit
PF12733 Cadherin-like, 1 hit
PF08305 NPCBM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00776 NPCBM, 1 hit
SM00710 PbH1, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49373 SSF49373, 2 hits
SSF49785 SSF49785, 1 hit
SSF51126 SSF51126, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E3EN28-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLDIGERIGE RPGGVTAALA AALICLAPLF STNTAQAAGG DVVSVADYGA
60 70 80 90 100
AADSGEDSAP AIIKAVDKAK ELAAEGKNVT IAFPKGRYDI YPDKAERRTL
110 120 130 140 150
YVSNTVGTNS SYKDKKIGIL LEDTKNITVD GQGSDFVFHG KMTTFAAINS
160 170 180 190 200
RNVTFKNFSV DFQVPTVIDL TVEKVDAGAK TATVYVPEEY NYRLSGSNIE
210 220 230 240 250
WYSDSSPYTG ATYWTASNAL PYVQLYDTKT GLTVRGDVWT NPIFQNVTGI
260 270 280 290 300
TDAGNHRLVF SYSSMSDKLA NATGISYQMR QTTRDHPGVF LWKDKDVTLK
310 320 330 340 350
GIDFRFLHGF GVVGQSTDTI TMDGLHFGTG EGTGRSTAGY ADFVQMSGCK
360 370 380 390 400
GVITVANSSF SNPHDDPINV HGTFLQVVEK ISDTKIKVRY MHNETAGFPS
410 420 430 440 450
FFVGDQVEFM TKGDMLPVSD SVRTVTAVDG PDGQGGDMGA GSGSLTDIVL
460 470 480 490 500
TLDSAIPSAV AVNSHVVENI TYTPEVNIHD NVFKETPTRG ILVTTRKKVT
510 520 530 540 550
IENNLFDGMG MAGIYISNDA QSWYESGPTR DVTIRGNTFR RSGSDAILVE
560 570 580 590 600
PTNPTVSTTD TVHKNMTIEG NTFYVNGNRV LNAKSVSDLT FRDNKIYREN
610 620 630 640 650
PDDTVTLGGD ADVALAVGDT RRIDATASVS QVSGSRLFRL NGCKQVVFGG
660 670 680 690 700
NTYDVGVKAG IDLANMGASE VNVSDDSAKV GADGLVPVTG SIAYVSDDAA
710 720 730 740 750
VASVDQDGTI TAVGEGETTV RTYVIAGARR MPGSVVNVRV SASTATAPTP
760 770 780 790 800
GTSADPLDGH PSSVATLSSA TIDGLSKSFD FKPGTLYYFG ADSALTARAA
810 820 830 840 850
FKATDADASV KATLNGKAID ATGADVKLAR GRNVIEATVT ATDGITANTY
860 870 880 890 900
RFVIDRIGGV DTGLAALSVG GNAISVEHGR LQYTASTMRS KTQVVASSFD
910 920 930 940 950
PTATLQLMRV NGSKRVPVGD AQQGSLTRDV TVYQGDNTFE LDVTSGGSTV
960 970 980 990 1000
SYKVAVTGTD SVYASDLAWE SATSGDPNTN PVRKDKSCGN NTITLWDGEK
1010 1020 1030 1040 1050
EQTFDKGIGT HAASRIVYDV SDLGAIRFEA YVGVDRELTG VDRDHANVDF
1060 1070 1080 1090 1100
QVMIDGEVVF EKTAMQHDTP MAKVSVDIPE GAKTITLAVG AGSETWGDHA
1110 1120 1130 1140 1150
DWADARFVGV EMPEAPQVTG LAVTGEGVKD GKLDMTVGQS VGLGVTVTPE
1160 1170 1180 1190 1200
DAVDQSVTWT VAGDAVSVGE DGTVKALKAG TATVTVASVA VPSVTASVTV
1210 1220 1230 1240 1250
TVAEKADPDP DPKPDPEPDP DPTPKPDPDP DPNPNPGPGD EPGTTTPGDG
1260 1270 1280 1290 1300
QKPNTDKDAD KNAGKDKNQS IAATGASIVP VGVLAVSMMA AGCALTGRKR

RES
Length:1,303
Mass (Da):136,792
Last modified:January 11, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDB622C8FB765F2B6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP002220 Genomic DNA Translation: ADO53462.1

NCBI Reference Sequences

More...
RefSeqi
WP_013363699.1, NC_014616.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ADO53462; ADO53462; BBIF_1257

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bbi:BBIF_1257

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002220 Genomic DNA Translation: ADO53462.1
RefSeqiWP_013363699.1, NC_014616.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

CAZyiCBM51 Carbohydrate-Binding Module Family 51
GH110 Glycoside Hydrolase Family 110

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO53462; ADO53462; BBIF_1257
KEGGibbi:BBIF_1257

Phylogenomic databases

HOGENOMiHOG000166201
OMAiYISNDAQ

Enzyme and pathway databases

BioCyciBBIF883062:G1GOD-1309-MONOMER

Family and domain databases

Gene3Di2.160.20.10, 2 hits
2.60.120.1060, 1 hit
InterProiView protein in InterPro
IPR039448 Beta_helix
IPR003343 Big_2
IPR025883 Cadherin-like_b_sandwich
IPR008979 Galactose-bd-like_sf
IPR013222 Glyco_hyd_98_carb-bd
IPR008964 Invasin/intimin_cell_adhesion
IPR038637 NPCBM_sf
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
PfamiView protein in Pfam
PF13229 Beta_helix, 1 hit
PF02368 Big_2, 1 hit
PF12733 Cadherin-like, 1 hit
PF08305 NPCBM, 1 hit
SMARTiView protein in SMART
SM00776 NPCBM, 1 hit
SM00710 PbH1, 6 hits
SUPFAMiSSF49373 SSF49373, 2 hits
SSF49785 SSF49785, 1 hit
SSF51126 SSF51126, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE3EN28_BIFBS
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E3EN28
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: June 5, 2019
This is version 43 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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