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Protein

Protein PBMUCL2

Gene

HCG22

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PBMUCL2
Alternative name(s):
HLA complex group 22
Panbronchiolitis-related mucin-like protein 2
Gene namesi
Name:HCG22
Synonyms:G2, PBMUCL2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:27780 HCG22
MIMi613918 gene
neXtProtiNX_E2RYF7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

DisGeNETi285834

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000041047123 – 251Protein PBMUCL2Add BLAST229

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi120N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiE2RYF7
PRIDEiE2RYF7
ProteomicsDBi15280

Expressioni

Tissue specificityi

Detected in the brain, lung, spleen, thymus and prostate.1 Publication

Structurei

3D structure databases

ProteinModelPortaliE2RYF7
SMRiE2RYF7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni153 – 25115 X 11 AA approximate repeatsAdd BLAST99

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi89 – 248Thr-richAdd BLAST160

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

InParanoidiE2RYF7

Family and domain databases

InterProiView protein in InterPro
IPR032059 Mucin-like
IPR037648 PBMUCL2
PANTHERiPTHR22467 PTHR22467, 2 hits
PfamiView protein in Pfam
PF16058 Mucin-like, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E2RYF7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRYVPLLLL LLLLRCSERG GGVNFGEKDA KVPGTWRDGV RVPGEGASWD
60 70 80 90 100
SDRASPERRY GIVGLSQSIS TKHPETSPKD SRIRENDVTA DGRTTEDHIT
110 120 130 140 150
ADPGTTEDSV TADPGTTEDN VTVDPGTTEG SVTADPATTK DYVSADPGTT
160 170 180 190 200
KDSVTADPGT TENFVTADPG TTKDSITADP RTTEDSVTAD PGTTKHSITV
210 220 230 240 250
DPGTTEDSVT ADPGTTKHSI TADPGTTEDS VTADPGTTED ETTKHGDTHL

L
Length:251
Mass (Da):26,282
Last modified:January 11, 2011 - v1
Checksum:iCC3DEAC2A4617A1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB560771 mRNA Translation: BAJ24155.1
CR759772 Genomic DNA No translation available.
RefSeqiNP_001335178.1, NM_001348249.1
UniGeneiHs.207528

Genome annotation databases

GeneIDi285834
KEGGihsa:285834

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB560771 mRNA Translation: BAJ24155.1
CR759772 Genomic DNA No translation available.
RefSeqiNP_001335178.1, NM_001348249.1
UniGeneiHs.207528

3D structure databases

ProteinModelPortaliE2RYF7
SMRiE2RYF7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiE2RYF7
PRIDEiE2RYF7
ProteomicsDBi15280

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi285834
KEGGihsa:285834

Organism-specific databases

CTDi285834
DisGeNETi285834
GeneCardsiHCG22
H-InvDBiHIX0165913
HIX0166084
HIX0166350
HIX0166804
HIX0167048
HIX0167336
HIX0207400
HGNCiHGNC:27780 HCG22
MIMi613918 gene
neXtProtiNX_E2RYF7
GenAtlasiSearch...

Phylogenomic databases

InParanoidiE2RYF7

Miscellaneous databases

PROiPR:E2RYF7
SOURCEiSearch...

Family and domain databases

InterProiView protein in InterPro
IPR032059 Mucin-like
IPR037648 PBMUCL2
PANTHERiPTHR22467 PTHR22467, 2 hits
PfamiView protein in Pfam
PF16058 Mucin-like, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPBMU2_HUMAN
AccessioniPrimary (citable) accession number: E2RYF7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: January 11, 2011
Last modified: July 18, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
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