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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-CFA-5660668 CLEC7A/inflammasome pathway
R-CFA-6798695 Neutrophil degranulation
R-CFA-844456 The NLRP3 inflammasome

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 6

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiE2RQ18
PRIDEiE2RQ18

Expressioni

Gene expression databases

BgeeiENSCAFG00000016865 Expressed in 3 organ(s), highest expression level in liver

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000024803

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 91PyrinInterPro annotationAdd BLAST91

Phylogenomic databases

eggNOGiENOG410J02A Eukaryota
ENOG4111XEQ LUCA
GeneTreeiENSGT00440000033973
InParanoidiE2RQ18
OMAiLRDIGMQ
OrthoDBiEOG091G0OWO

Family and domain databases

InterProiView protein in InterPro
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
PfamiView protein in Pfam
PF02758 PYRIN, 1 hit
SMARTiView protein in SMART
SM01289 PYRIN, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50824 DAPIN, 1 hit

Sequencei

Sequence statusi: Complete.

E2RQ18-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRIRDAILD ALENLTAEEF KKFKMKLLSV PLREGYGRIP RGTLLPMDAM
60 70 80 90 100
DLTDKLVSFY LEEYGAELTA VVLRDIGMQE TAERLQETSH KGKHNPSTPC
110
RGPDPCASSY TLSLY
Length:115
Mass (Da):12,923
Last modified:October 31, 2012 - v2
Checksum:iF5E0F3F2FB596B44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004378 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000026697; ENSCAFP00000024803; ENSCAFG00000016865

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004378 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000024803

Proteomic databases

PaxDbiE2RQ18
PRIDEiE2RQ18

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000026697; ENSCAFP00000024803; ENSCAFG00000016865

Phylogenomic databases

eggNOGiENOG410J02A Eukaryota
ENOG4111XEQ LUCA
GeneTreeiENSGT00440000033973
InParanoidiE2RQ18
OMAiLRDIGMQ
OrthoDBiEOG091G0OWO

Enzyme and pathway databases

ReactomeiR-CFA-5660668 CLEC7A/inflammasome pathway
R-CFA-6798695 Neutrophil degranulation
R-CFA-844456 The NLRP3 inflammasome

Gene expression databases

BgeeiENSCAFG00000016865 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

InterProiView protein in InterPro
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
PfamiView protein in Pfam
PF02758 PYRIN, 1 hit
SMARTiView protein in SMART
SM01289 PYRIN, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50824 DAPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE2RQ18_CANLF
AccessioniPrimary (citable) accession number: E2RQ18
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: October 31, 2012
Last modified: September 12, 2018
This is version 60 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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