Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

TNFRSF1A associated via death domain

Gene

TRADD

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-3371378 Regulation by c-FLIP
R-CFA-5213460 RIPK1-mediated regulated necrosis
R-CFA-5218900 CASP8 activity is inhibited
R-CFA-5357786 TNFR1-induced proapoptotic signaling
R-CFA-5357905 Regulation of TNFR1 signaling
R-CFA-5357956 TNFR1-induced NFkappaB signaling pathway
R-CFA-69416 Dimerization of procaspase-8
R-CFA-75893 TNF signaling

Names & Taxonomyi

Protein namesi
Submitted name:
TNFRSF1A associated via death domainImported
Gene namesi
Name:TRADDImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 5

Organism-specific databases

VGNCiVGNC:47761 TRADD

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE2REX3

Expressioni

Gene expression databases

BgeeiENSCAFG00000020382

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000030230

Structurei

3D structure databases

ProteinModelPortaliE2REX3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini215 – 305DeathInterPro annotationAdd BLAST91

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili272 – 292Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IF81 Eukaryota
ENOG4111IRA LUCA
GeneTreeiENSGT00390000002016
InParanoidiE2REX3
OMAiFCGRQPC
OrthoDBiEOG091G0DXR
TreeFamiTF331882

Family and domain databases

Gene3Di3.30.70.680, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR035712 TRADD
IPR009095 TRADD_N
IPR036729 TRADD_N_sf
PANTHERiPTHR14913 PTHR14913, 1 hit
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF09034 TRADD_N, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD182470 TRADD_N, 1 hit
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF55044 SSF55044, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

E2REX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGPDGLEE WVGSAYLFVE SSLDKVVLSD AYAQAQQKVP VYRALRTALA
60 70 80 90 100
ESGGSPDVLQ MLKIHRSEPQ LIVQLRFCGR QPCSRFLRAY REGSLRAALQ
110 120 130 140 150
ACLAAALAQR SMPLQLELRA GAERLDTLLT DEERCLSCIF AQKPDRLRDE
160 170 180 190 200
ELSELEDALQ NLTCGSGRQD GDVEVAPAPS QSLATSLSEE KPPPPPPPGQ
210 220 230 240 250
TFLFQGQPIV NRPLSLQDQQ KFARSVGLKW RKVGRSLQRG CRALKDPALD
260 270 280 290 300
SLAYEYEREG LYEQAFQLLK RFVQAEGRRA TLQRLVEALE ENELTSLAED
310
LLGLTNPDGS LA
Length:312
Mass (Da):34,523
Last modified:November 30, 2010 - v1
Checksum:i396B958A2D681A8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004128 Genomic DNA No translation available.
RefSeqiXP_853998.2, XM_848905.4

Genome annotation databases

EnsembliENSCAFT00000032460; ENSCAFP00000030230; ENSCAFG00000020382
GeneIDi611262

Similar proteinsi

Entry informationi

Entry nameiE2REX3_CANLF
AccessioniPrimary (citable) accession number: E2REX3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: June 20, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health