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Protein
Submitted name:

G protein subunit beta 2

Gene

GNB2

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-1296041 Activation of G protein gated Potassium channels
R-CFA-163359 Glucagon signaling in metabolic regulation
R-CFA-202040 G-protein activation
R-CFA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
R-CFA-392170 ADP signalling through P2Y purinoceptor 12
R-CFA-392451 G beta:gamma signalling through PI3Kgamma
R-CFA-392851 Prostacyclin signalling through prostacyclin receptor
R-CFA-400042 Adrenaline,noradrenaline inhibits insulin secretion
R-CFA-4086398 Ca2+ pathway
R-CFA-416476 G alpha (q) signalling events
R-CFA-416482 G alpha (12/13) signalling events
R-CFA-418217 G beta:gamma signalling through PLC beta
R-CFA-418555 G alpha (s) signalling events
R-CFA-418592 ADP signalling through P2Y purinoceptor 1
R-CFA-418594 G alpha (i) signalling events
R-CFA-418597 G alpha (z) signalling events
R-CFA-420092 Glucagon-type ligand receptors
R-CFA-428930 Thromboxane signalling through TP receptor
R-CFA-432040 Vasopressin regulates renal water homeostasis via Aquaporins
R-CFA-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-CFA-500657 Presynaptic function of Kainate receptors
R-CFA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
R-CFA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Names & Taxonomyi

Protein namesi
Submitted name:
G protein subunit beta 2Imported
Gene namesi
Name:GNB2Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 6

Organism-specific databases

VGNCiVGNC:41313 GNB2

PTM / Processingi

Proteomic databases

PRIDEiE2RD95

Expressioni

Gene expression databases

BgeeiENSCAFG00000014282

Structurei

3D structure databases

ProteinModelPortaliE2RD95
SMRiE2RD95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 340WD_REPEATS_REGIONInterPro annotationAdd BLAST290
Repeati51 – 92WDPROSITE-ProRule annotationAdd BLAST42
Repeati139 – 179WDPROSITE-ProRule annotationAdd BLAST41
Repeati180 – 221WDPROSITE-ProRule annotationAdd BLAST42
Repeati222 – 263WDPROSITE-ProRule annotationAdd BLAST42
Repeati273 – 307WDPROSITE-ProRule annotationAdd BLAST35
Repeati308 – 340WDPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 24Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119239
KOiK04537
TreeFamiTF106149

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19850 PTHR19850, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 7 hits
PRINTSiPR00319 GPROTEINB
PR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 3 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

E2RD95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSELEQLRQE AEQLRNQIRD ARKACGDSTL TQITAGLDPV GRIQMRTRRT
60 70 80 90 100
LRGHLAKIYA MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV
110 120 130 140 150
MTCAYAPSGN FVACGGLDNI CSIYSLKTRE GNVRVSRELP GHTGYLSCCR
160 170 180 190 200
FLDDNQIITS SGDTTCALWD IETGQQTVGF AGHSGDVMSL SLAPDGRTFV
210 220 230 240 250
SGACDASIKL WDVRDSMCRQ TFIGHESDIN AVAFFPNGYA FTTGSDDATC
260 270 280 290 300
RLFDLRADQE LLMYSHDNII CGITSVAFSR SGRLLLAGYD DFNCNIWDAM
310 320 330 340
KGDRAGVLAG HDNRVSCLGV TDDGMAVATG SWDSFLKIWN
Length:340
Mass (Da):37,331
Last modified:November 30, 2010 - v1
Checksum:i5D08FFA240ADEEE6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004274 Genomic DNA No translation available.
RefSeqiXP_536861.2, XM_536861.5

Genome annotation databases

EnsembliENSCAFT00000038242; ENSCAFP00000033929; ENSCAFG00000014282
GeneIDi479733
KEGGicfa:479733

Similar proteinsi

Entry informationi

Entry nameiE2RD95_CANLF
AccessioniPrimary (citable) accession number: E2RD95
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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