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Protein
Submitted name:

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

Gene

ST3GAL6

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • beta-galactoside alpha-2,3-sialyltransferase activity Source: UniProtKB
  • sialyltransferase activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseSAAS annotation, Transferase

Enzyme and pathway databases

ReactomeiR-CFA-2022854 Keratan sulfate biosynthesis
R-CFA-4085001 Sialic acid metabolism

Names & Taxonomyi

Protein namesi
Submitted name:
ST3 beta-galactoside alpha-2,3-sialyltransferase 6Imported
Gene namesi
Name:ST3GAL6Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 33

Organism-specific databases

VGNCiVGNC:46854 ST3GAL6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 31HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi118 ↔ 271UniRule annotation

Proteomic databases

PaxDbiE2RCV7

Expressioni

Gene expression databases

BgeeiENSCAFG00000009190 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000013517

Structurei

3D structure databases

ProteinModelPortaliE2RCV7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
GeneTreeiENSGT00760000119095
InParanoidiE2RCV7
KOiK03792
OMAiTLAFHIC
OrthoDBiEOG091G098L
TreeFamiTF354325

Family and domain databases

Gene3Di3.90.1480.20, 1 hit
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
IPR012163 Sialyl_trans
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit
PIRSFiPIRSF005557 Sialyl_trans, 2 hits

Sequencei

Sequence statusi: Complete.

E2RCV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRGYLVAIFL SAVFLYYVLH CILWGTNIYW VPPVEMKRRN KIQPCLAKPA
60 70 80 90 100
FASLLRFHQF HPFLCAADFK KIASLYGSDK FDLPYGIRTS AEYFRLALSK
110 120 130 140 150
LQSCDLFDEF DNVPCKKCVV VGNGGVLKNK TLGEKIDSYD VIIRMNNGPV
160 170 180 190 200
LGHEEEVGRR TTFRLFYPES VFSDPNHNDP NTTAILTAFK PLDLKWLWEV
210 220 230 240 250
LTGGKINTNG FWKKPALNLI YKPYQIRILD PFIIRMAAYE LLHFPKVFPK
260 270 280 290 300
NQKPKHPTTG IIAITLAFHI CHEVHLAGFK YNFSDLKSPL HYYGNATMSL
310 320 330
MNKNAYHNVT AEQLFLKDIL EKNFVINLTE D
Length:331
Mass (Da):38,108
Last modified:November 30, 2010 - v1
Checksum:i3EA47B33D2571E2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03016928 Genomic DNA No translation available.
AAEX03016929 Genomic DNA No translation available.
AAEX03016930 Genomic DNA No translation available.
AAEX03016931 Genomic DNA No translation available.
AAEX03016932 Genomic DNA No translation available.
RefSeqiXP_005639432.1, XM_005639375.2
XP_005639433.1, XM_005639376.2
XP_005639434.1, XM_005639377.2
XP_005639435.1, XM_005639378.2
XP_005639436.1, XM_005639379.2
XP_013965568.1, XM_014110093.1
XP_848351.1, XM_843258.4

Genome annotation databases

EnsembliENSCAFT00000014615; ENSCAFP00000013517; ENSCAFG00000009190
GeneIDi478535
KEGGicfa:478535

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03016928 Genomic DNA No translation available.
AAEX03016929 Genomic DNA No translation available.
AAEX03016930 Genomic DNA No translation available.
AAEX03016931 Genomic DNA No translation available.
AAEX03016932 Genomic DNA No translation available.
RefSeqiXP_005639432.1, XM_005639375.2
XP_005639433.1, XM_005639376.2
XP_005639434.1, XM_005639377.2
XP_005639435.1, XM_005639378.2
XP_005639436.1, XM_005639379.2
XP_013965568.1, XM_014110093.1
XP_848351.1, XM_843258.4

3D structure databases

ProteinModelPortaliE2RCV7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000013517

Proteomic databases

PaxDbiE2RCV7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000014615; ENSCAFP00000013517; ENSCAFG00000009190
GeneIDi478535
KEGGicfa:478535

Organism-specific databases

CTDi10402
VGNCiVGNC:46854 ST3GAL6

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
GeneTreeiENSGT00760000119095
InParanoidiE2RCV7
KOiK03792
OMAiTLAFHIC
OrthoDBiEOG091G098L
TreeFamiTF354325

Enzyme and pathway databases

ReactomeiR-CFA-2022854 Keratan sulfate biosynthesis
R-CFA-4085001 Sialic acid metabolism

Gene expression databases

BgeeiENSCAFG00000009190 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

Gene3Di3.90.1480.20, 1 hit
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
IPR012163 Sialyl_trans
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit
PIRSFiPIRSF005557 Sialyl_trans, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE2RCV7_CANLF
AccessioniPrimary (citable) accession number: E2RCV7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: November 7, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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