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Protein
Submitted name:

CD79b molecule

Gene

CD79B

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-5690714 CD22 mediated BCR regulation
R-CFA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Names & Taxonomyi

Protein namesi
Submitted name:
CD79b moleculeImported
Gene namesi
Name:CD79BImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 9

Organism-specific databases

VGNCiVGNC:38974 CD79B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei155 – 176HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_500316325130 – 214Sequence analysisAdd BLAST185

Proteomic databases

PaxDbiE2RCN1

Expressioni

Gene expression databases

BgeeiENSCAFG00000012677 Expressed in 3 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000018654

Structurei

3D structure databases

ProteinModelPortaliE2RCN1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 128Ig-likeInterPro annotationAdd BLAST93

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J02H Eukaryota
ENOG410Z4S5 LUCA
GeneTreeiENSGT00510000048811
InParanoidiE2RCN1
OMAiDQTATYE
OrthoDBiEOG091G0O8L
TreeFamiTF336032

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003110 Phos_immunorcpt_sig_ITAM
PfamiView protein in Pfam
PF07679 I-set, 1 hit
PF02189 ITAM, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00077 ITAM, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS51055 ITAM_1, 1 hit

Sequencei

Sequence statusi: Complete.

E2RCN1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGLVLSPVP HNWLVVLLLL LSGVPAAKTE DRHQDPKGST CSGIWQSPRF
60 70 80 90 100
IARKRGAVVE IRCHTKDVGA VSWLWKREMD LEPKPLPRED RLLQSQNDSV
110 120 130 140 150
ATLTIQGIQF SDNGIYFCQQ KCSKGSFSKG CGTELRVMGF STLAQLKRRN
160 170 180 190 200
TLKDGIIMIQ TLLIILFIIV PIFLLLDKDD SKAGMDEDHT YEGLNIDQTA
210
TYEDIVTLRT GEVK
Length:214
Mass (Da):23,942
Last modified:October 31, 2012 - v2
Checksum:i552A256DD04E3448
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03006359 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000020113; ENSCAFP00000018654; ENSCAFG00000012677

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03006359 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE2RCN1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000018654

Proteomic databases

PaxDbiE2RCN1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000020113; ENSCAFP00000018654; ENSCAFG00000012677

Organism-specific databases

VGNCiVGNC:38974 CD79B

Phylogenomic databases

eggNOGiENOG410J02H Eukaryota
ENOG410Z4S5 LUCA
GeneTreeiENSGT00510000048811
InParanoidiE2RCN1
OMAiDQTATYE
OrthoDBiEOG091G0O8L
TreeFamiTF336032

Enzyme and pathway databases

ReactomeiR-CFA-5690714 CD22 mediated BCR regulation
R-CFA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Gene expression databases

BgeeiENSCAFG00000012677 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003110 Phos_immunorcpt_sig_ITAM
PfamiView protein in Pfam
PF07679 I-set, 1 hit
PF02189 ITAM, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00077 ITAM, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS51055 ITAM_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE2RCN1_CANLF
AccessioniPrimary (citable) accession number: E2RCN1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: October 31, 2012
Last modified: September 12, 2018
This is version 50 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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