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Protein
Submitted name:

ATP binding cassette subfamily C member 11

Gene

ABCC11

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi545 – 552ATPPROSITE-ProRule annotation8
Nucleotide bindingi1179 – 1186ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP binding cassette subfamily C member 11Imported
Gene namesi
Name:ABCC11Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 2

Organism-specific databases

VGNCiVGNC:37438 ABCC11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei161 – 182HelicalSequence analysisAdd BLAST22
Transmembranei197 – 224HelicalSequence analysisAdd BLAST28
Transmembranei273 – 295HelicalSequence analysisAdd BLAST23
Transmembranei301 – 319HelicalSequence analysisAdd BLAST19
Transmembranei378 – 402HelicalSequence analysisAdd BLAST25
Transmembranei414 – 436HelicalSequence analysisAdd BLAST23
Transmembranei804 – 827HelicalSequence analysisAdd BLAST24
Transmembranei865 – 886HelicalSequence analysisAdd BLAST22
Transmembranei934 – 956HelicalSequence analysisAdd BLAST23
Transmembranei962 – 981HelicalSequence analysisAdd BLAST20
Transmembranei1057 – 1077HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE2RBC4

Expressioni

Gene expression databases

BgeeiENSCAFG00000010061 Expressed in 2 organ(s), highest expression level in adult mammalian kidney

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000014807

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini165 – 441ABC transmembrane type-1InterPro annotationAdd BLAST277
Domaini506 – 733ABC transporterInterPro annotationAdd BLAST228
Domaini808 – 1086ABC transmembrane type-1InterPro annotationAdd BLAST279
Domaini1145 – 1380ABC transporterInterPro annotationAdd BLAST236

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0054 Eukaryota
COG1132 LUCA
GeneTreeiENSGT00880000137856
InParanoidiE2RBC4
OMAiFEGVYYG
OrthoDBiEOG091G01TC
TreeFamiTF352085

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030251 ABCC11
IPR027417 P-loop_NTPase
PANTHERiPTHR24223:SF168 PTHR24223:SF168, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E2RBC4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKKRVHWVP RSSGGLVNLG MDMSNDMVSG LSYNTYTVGD GSWSRQVKKP
60 70 80 90 100
EAPATVLPWE RYNAAWRTMI PFRPKPKFPA PQPMDDAGLF SYLTMSWLTP
110 120 130 140 150
FMIQGVRRRL NENTIPQLSV HDASDKNAKR LCLLWEEEVS RHGIEKASVL
160 170 180 190 200
RVMMRFQRTR ALFDIFLGCL FSVMSVLGPM LFIPKILEYS EERSGNIAYG
210 220 230 240 250
VGLCFALFFT ECLKSLSLCS CWVLNQRTGV RFRSAVFSFA FEKLIQFKSL
260 270 280 290 300
THITTGEAIS FFTSDVNYLF EGVYYGPLIW LISSLLISCT LSSYFILGPT
310 320 330 340 350
VLSATFCYLL ILPVEVLLIK KIVKIHSHLS EISDQRIRVT SEVLTCIKLI
360 370 380 390 400
KMYAWEKPFE KIIKDLRRKE RRLLEKSGII QSLTTASLFI APTVATTVMF
410 420 430 440 450
LIHTCLQLKL TVSLVFTVVG TLIPLRLSVF FVPFAVKGLT NSKSAAERFK
460 470 480 490 500
KFFLQESPVL YVQALKDPSK AVVLEEATLS WRQTCPGIVN GAAELEKNGC
510 520 530 540 550
APEGMTRAQP ARGALRPEDT RDSLLPELQK LNLVVSKGTM LGVCGNTGSG
560 570 580 590 600
KSSLLSAILG EMHLLEGSVG VHGSLAYVPQ QAWIIGGNVR ENILMGRQYD
610 620 630 640 650
KARYLQVLHC CSLNHDLEIL PFGDMTEIGE RGLNLSGGQK QRISLARAVY
660 670 680 690 700
SDRELYLLDD PLSAVDTHVG KHIFEECIKK MLSGKTIILV THQLQYLALC
710 720 730 740 750
DQIIFLEDGK ICEKGIHSEL IQKKGRYAQL IQKMLGKATQ DKLQDTVETA
760 770 780 790 800
EDPQGQGQAW TTFQEEILHS DPVLENQLTR KEMMEEGSLG WRVYHHYIRA
810 820 830 840 850
SGGYMVFAIV FFLMMGIIFL TTFNFWWLSY WLEQGSGTNS SQENNGTTAD
860 870 880 890 900
PGDILDNPQL LCYQLVYGLS VLLLICIGVC FSGFFAKITR KASSALHNEL
910 920 930 940 950
LNKVSCSPMS FFDTTPTGRL LNCFAGDLDA MDQLLPVVAE EFLLLSLMVV
960 970 980 990 1000
AILLAVSVLS PYILLMGVIL FTLCLIFFSM FKAPINVFKR LENYSRSPLF
1010 1020 1030 1040 1050
SHILTTLQGL SSIHVYGKAE DFISEFKRLT DAHNNYLLMF LSSLRWISLR
1060 1070 1080 1090 1100
LEITTNLLAF AVTLFVAFGI SSAPYSYKAM AISLILQLAS NFQATARIGS
1110 1120 1130 1140 1150
ETEAYFTAVE RICQYMKKNE MCVPESPLCI EGTSCPPGWP QHGEITFQDY
1160 1170 1180 1190 1200
HMKYRDNTPI ILNGINLTIH GHEVVGIVGR TGSGKSSLGV ALFRLVEPTA
1210 1220 1230 1240 1250
GRILIDGVDI CSINLEDLRS KFSIVPQDPV LLSGTIRFNL DPFDRYTDEQ
1260 1270 1280 1290 1300
IWDVLEKTFL SMTISKLPQR LQAEVVESGR NFFSVGEKQL LCIARALLRN
1310 1320 1330 1340 1350
SKIILIDEAT ASIDMETDSL IQHTIREAFQ GCTVLVIAHR ITTVLSCDRV
1360 1370 1380
LVMNNGKVVE FDRPEVLQQK PESAFAALLA TANSSLS
Length:1,387
Mass (Da):155,302
Last modified:October 31, 2012 - v2
Checksum:i092124E04AA5C785
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J9P6G2J9P6G2_CANLF
ATP binding cassette subfamily C me...
ABCC11
1,205Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03001639 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000016007; ENSCAFP00000014807; ENSCAFG00000010061

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03001639 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000014807

Proteomic databases

PaxDbiE2RBC4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000016007; ENSCAFP00000014807; ENSCAFG00000010061

Organism-specific databases

VGNCiVGNC:37438 ABCC11

Phylogenomic databases

eggNOGiKOG0054 Eukaryota
COG1132 LUCA
GeneTreeiENSGT00880000137856
InParanoidiE2RBC4
OMAiFEGVYYG
OrthoDBiEOG091G01TC
TreeFamiTF352085

Gene expression databases

BgeeiENSCAFG00000010061 Expressed in 2 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030251 ABCC11
IPR027417 P-loop_NTPase
PANTHERiPTHR24223:SF168 PTHR24223:SF168, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE2RBC4_CANLF
AccessioniPrimary (citable) accession number: E2RBC4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: October 31, 2012
Last modified: November 7, 2018
This is version 63 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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