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Protein
Submitted name:

Uncharacterized protein

Gene

BCL10

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-1169091 Activation of NF-kappaB in B cells
R-CFA-202424 Downstream TCR signaling
R-CFA-2871837 FCERI mediated NF-kB activation
R-CFA-5607764 CLEC7A (Dectin-1) signaling
R-CFA-8866654 E3 ubiquitin ligases ubiquitinate target proteins

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:BCL10Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE2RA73

Expressioni

Gene expression databases

BgeeiENSCAFG00000020285 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000030083

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 87CARDInterPro annotationAdd BLAST75

Phylogenomic databases

eggNOGiENOG410IVMM Eukaryota
ENOG4111JRA LUCA
GeneTreeiENSGT00490000043442
InParanoidiE2RA73
KOiK07368
OMAiRHYLCDK
OrthoDBiEOG091G0UTQ
TreeFamiTF328636

Family and domain databases

InterProiView protein in InterPro
IPR033238 BCL10/E10
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
PANTHERiPTHR34920 PTHR34920, 1 hit
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit

Sequencei

Sequence statusi: Complete.

E2RA73-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPAAPSLTE EDLTEVKKDA LENLRVYLCE KIIAERHFDH LRAKKILSRE
60 70 80 90 100
DTEEISCRTS SRKRAGKLLD YLQENPKGLD TLVESIRREK TQNFLIQKIT
110 120 130 140 150
DEVLKLRNIK LEHLKGLKCS SCEPFPDGAT NNFSRSNSDE SNFSEKLRAS
160 170 180 190 200
TVIYHPEGES STAPFFSTES SLNLPVLEVG RTENPTFSST TLPRPGDPGA
210 220 230
PPLPPELQLE DGGTCGNSSE MFLPLRSRAV SHQ
Length:233
Mass (Da):26,071
Last modified:November 30, 2010 - v1
Checksum:iB218DEB3EAB69479
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004854 Genomic DNA No translation available.
RefSeqiXP_547304.2, XM_547304.5

Genome annotation databases

EnsembliENSCAFT00000032304; ENSCAFP00000030083; ENSCAFG00000020285
GeneIDi490183
KEGGicfa:490183

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03004854 Genomic DNA No translation available.
RefSeqiXP_547304.2, XM_547304.5

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000030083

Proteomic databases

PaxDbiE2RA73

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000032304; ENSCAFP00000030083; ENSCAFG00000020285
GeneIDi490183
KEGGicfa:490183

Organism-specific databases

CTDi8915

Phylogenomic databases

eggNOGiENOG410IVMM Eukaryota
ENOG4111JRA LUCA
GeneTreeiENSGT00490000043442
InParanoidiE2RA73
KOiK07368
OMAiRHYLCDK
OrthoDBiEOG091G0UTQ
TreeFamiTF328636

Enzyme and pathway databases

ReactomeiR-CFA-1169091 Activation of NF-kappaB in B cells
R-CFA-202424 Downstream TCR signaling
R-CFA-2871837 FCERI mediated NF-kB activation
R-CFA-5607764 CLEC7A (Dectin-1) signaling
R-CFA-8866654 E3 ubiquitin ligases ubiquitinate target proteins

Gene expression databases

BgeeiENSCAFG00000020285 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

InterProiView protein in InterPro
IPR033238 BCL10/E10
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
PANTHERiPTHR34920 PTHR34920, 1 hit
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE2RA73_CANLF
AccessioniPrimary (citable) accession number: E2RA73
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 10, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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