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Protein
Submitted name:

Acyl-CoA dehydrogenase very long chain

Gene

ACADVL

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

ReactomeiR-CFA-77305 Beta oxidation of palmitoyl-CoA to myristoyl-CoA

Names & Taxonomyi

Protein namesi
Submitted name:
Acyl-CoA dehydrogenase very long chainImported
Gene namesi
Name:ACADVLImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 5

Organism-specific databases

VGNCiVGNC:53258 ACADVL

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE2QXA3
PRIDEiE2QXA3

Expressioni

Gene expression databases

BgeeiENSCAFG00000016016

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000023601

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini127 – 240Acyl-CoA_dh_NInterPro annotationAdd BLAST114
Domaini244 – 346Acyl-CoA_dh_MInterPro annotationAdd BLAST103
Domaini358 – 504Acyl-CoA_dh_1InterPro annotationAdd BLAST147

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0137 Eukaryota
COG1960 LUCA
GeneTreeiENSGT00760000119007
InParanoidiE2QXA3
OMAiNAFMGLR
OrthoDBiEOG091G04BS
TreeFamiTF105053

Family and domain databases

Gene3Di1.10.540.10, 1 hit
InterProiView protein in InterPro
IPR006089 Acyl-CoA_DH_CS
IPR006091 Acyl-CoA_Oxase/DH_cen-dom
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR013786 AcylCoA_DH/ox_N
IPR037069 AcylCoA_DH/ox_N_sf
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF00441 Acyl-CoA_dh_1, 1 hit
PF02770 Acyl-CoA_dh_M, 1 hit
PF02771 Acyl-CoA_dh_N, 1 hit
SUPFAMiSSF47203 SSF47203, 1 hit
SSF56645 SSF56645, 1 hit
PROSITEiView protein in PROSITE
PS00072 ACYL_COA_DH_1, 1 hit
PS00073 ACYL_COA_DH_2, 1 hit

Sequencei

Sequence statusi: Complete.

E2QXA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRWRPEAQPP RCIVDDESRP DQDRGDRSGW EMQAARMAPS VGRQLRRLGV
60 70 80 90 100
GSSRPSALLG QPLPGPACRP YASGAAQAVL EKSDSHSSEA PTREKQAKAE
110 120 130 140 150
SKSFAAGMFK GQLTTDQVFP YPSVLSEEQT QFLKELVGPV SRFFEEVNDP
160 170 180 190 200
AKNDTLEKVE ETTLQGLKEL GAFGLQVPSE LGGVGLCNTQ YARLVEIVGT
210 220 230 240 250
HDLGVGITLG AHQSIGFKGI LLFGTKAQKE KYLPKLASGE SIAAFCLTEP
260 270 280 290 300
SSGSDAASIR SSAVPSPCGK YYTLNGSKIW ISNGGLADVF TVFAKTPVTD
310 320 330 340 350
AATGAVKEKI TAFVVERSFG GVTHGPPEKK MGIKASNTAE VYFDSVRVPA
360 370 380 390 400
ENVLGEVGSG FKVAMHILNN GRFGMAAALA GTMRGIIAKA VDHAANRTQF
410 420 430 440 450
GEKIHNFGLI QEKLARMAML QYVTESMAYM VSANMDQGST DFQIEAAISK
460 470 480 490 500
IFGSEAAWKV TDECIQILGG MGFMKEPGVE RVLRDLRIFR IFEGTNDILR
510 520 530 540 550
LFVALQGCMD KGKELSGLGN ALKNPFGNAG LLLGEAGKQL RRRAGLGSGL
560 570 580 590 600
SLSGIIHQEL NRSGELTVQA LEQFATVVEA KLIKHKKGIV NEQFVLQRLA
610 620 630 640 650
DSAIDLYAMV VVLSSRASRS LSEGHPTAQH EKMLCDSWCI EAAARVRETM
660 670 680
AALQSDPQQQ ELFRNFKSIS KALVERGGMV TSNPLGF
Length:687
Mass (Da):74,041
Last modified:October 31, 2012 - v2
Checksum:iB759EFBADF852DDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03003605 Genomic DNA No translation available.
AAEX03003606 Genomic DNA No translation available.
AAEX03003607 Genomic DNA No translation available.
AAEX03003608 Genomic DNA No translation available.
AAEX03003609 Genomic DNA No translation available.
AAEX03003610 Genomic DNA No translation available.
AAEX03003611 Genomic DNA No translation available.
AAEX03003612 Genomic DNA No translation available.
AAEX03003613 Genomic DNA No translation available.
AAEX03003614 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000025417; ENSCAFP00000023601; ENSCAFG00000016016

Similar proteinsi

Entry informationi

Entry nameiE2QXA3_CANLF
AccessioniPrimary (citable) accession number: E2QXA3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: October 31, 2012
Last modified: April 25, 2018
This is version 52 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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