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Protein
Submitted name:

MAP kinase activating death domain

Gene

MADD

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-5357905 Regulation of TNFR1 signaling
R-CFA-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Submitted name:
MAP kinase activating death domainImported
Gene namesi
Name:MADDImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 18

Organism-specific databases

VGNCiVGNC:42917 MADD

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE2QTJ4

Expressioni

Gene expression databases

BgeeiENSCAFG00000008656

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000012742

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 566UDENNInterPro annotationAdd BLAST553

Phylogenomic databases

eggNOGiKOG3570 Eukaryota
ENOG410XP23 LUCA
GeneTreeiENSGT00760000118819
InParanoidiE2QTJ4
OMAiKRLVDCC
OrthoDBiEOG091G00AV
TreeFamiTF318583

Family and domain databases

InterProiView protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR037516 Tripartite_DENN
IPR005113 uDENN_dom
PfamiView protein in Pfam
PF02141 DENN, 1 hit
PF03456 uDENN, 1 hit
SMARTiView protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
SM00800 uDENN, 1 hit
PROSITEiView protein in PROSITE
PS50211 DENN, 1 hit

Sequencei

Sequence statusi: Complete.

E2QTJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQKKKFCPR LLDYLVIVGA RHPSSDSVAQ TPELLRRYPL EDHAEFPLPP
60 70 80 90 100
DVVFFCQPEG CLSVRQRRMS LRDDTSFVFT LTDKDTGVTR YGICVNFYRS
110 120 130 140 150
FQKRMPKDKG DGGAGSRGKE GPRATCAPEE IGTESSESGL SLQPPSADSA
160 170 180 190 200
PPNVTQSPRG KPRAKTGSRS RNSTLTSLCV LSHYPFFSTF RECLYTLKRL
210 220 230 240 250
VDCCSERLLG KKLGIPRGIQ RDTMWRIFTG SLLVEEKSSA LLHDLREIEA
260 270 280 290 300
WIYRLLRSPV PVSGQKRVDI EVLPQELQQA LTFALPDPSR FTLVDFPLHL
310 320 330 340 350
PLELLGVDAC LQVLTCILLE HKVVLQSRDY NALSMSVMAF VAMIYPLEYM
360 370 380 390 400
FPVIPLLPTC MASAEQLLLA PTPYIIGVPA SFFLYKLDFK MPDDVWLVDL
410 420 430 440 450
DSNRVIAPTN AEVLPILPEP ESLELKKHLK QALASMSLNT QPILNLEKFH
460 470 480 490 500
EGQEIPLLLG RPSNDLQSTP STEFNPLIYG NDVDSVDVAT RVAMVRFFNS
510 520 530 540 550
PNVLQGFQMH TRTLRLFPRP VVAFQAGSFL ASRPRQTPFA EKLARTQAVE
560 570 580 590 600
YFGEWILNPT NYAFQRIHNN MFDPALIGDK PKWYAHQLQP IHYRVYDSNS
610 620 630 640 650
QLAEALSVPP ERDSDSDPTD DSGSDSMDYD DSSSSYSSLG DFVSEMMKCD
660 670 680 690 700
INGDTPNVDP LTHAALGDAS EVEIDELQNQ KESEEPGPDS ENSQENLPLR
710 720 730 740 750
SSSSTTASSS PSTVIHGANS EPADSTEVDD KAAVGVSKPP PTVPPSIGKS
760 770 780 790 800
NVDRRQTEIG EGSVRRRTYD NPYFEPQYGF PPEEEDDEQG ESYTPRFSQH
810 820 830 840 850
VNGNRAQKML RPNSLKLASD SDAESDSRAS SPTSTVSNTS TEGFGGIMSF
860 870 880 890 900
ASSLYRNHST SFSLSNLTLP TKGAREKTTP FPSLKVFGLN TLMEIVTEAG
910 920 930 940 950
PGSGEGNRRA LVDQKSSVIK HSPTVKREPP SPQGRSSNSS ENQQFLKEVV
960 970 980 990 1000
HSVLDGQGVG WLNMKKVRRL LESEQLRVFV LSKLNRTVQS EDDARQDVIP
1010 1020 1030 1040 1050
DVEISRKVYK GMLDLLKCTV LSLEQSYAHA GLGGMASIFG LLEIAQTHYY
1060 1070 1080 1090 1100
SKEPDKRKRS PTESVNTPVG KDPGLAGRGD PKAMAQLRVP QLGPRAPSAA
1110 1120 1130 1140 1150
GKGPKELDTR SLKEENFVAS VELWNKHQEV KKQKALEKQR PEVIKPVFDL
1160 1170 1180 1190 1200
GETEEKKSQI SADSGVSLTS GSQRTDTDSV IGVSPAVMIR SSSQDSEVST
1210 1220 1230 1240 1250
VVSNSSGETL GADSDLSSNA GDGPGGEGSA HLASSRGTLS DSEIETNSAT
1260 1270 1280 1290 1300
STIFGKAHSL KPSVKEKLVG SPVRSSEDVS QRVYLYEGLL GRDKGSMWDQ
1310 1320 1330 1340 1350
LEDAAMETFS ISKERSTLWD QMQFWEDAFL DAVMLEREGM GMDQGPQEMI
1360 1370 1380 1390 1400
DRYLSLGEHD RKRLEDDEDR LLATLLHNLI SYMLLMKVNK NDIRKKVRRL
1410 1420 1430 1440 1450
MGKSHIGLVY SQQINEVLDQ LVNLNGRDLS IRSSGSRHMK KQTFVVHAGT
1460 1470 1480 1490 1500
DTNGDIFFME VCDDCVVLRS NIGTVYERWW YEKLINMTYC PKTKVLCLWR
1510 1520 1530 1540 1550
RNGSETQLNK FYTKKCRELY YCVKDSMERA AARQQSIKPG PELGGEFPVQ
1560 1570 1580 1590 1600
DMKTGEGGLL QVTLEGINLK FMHNQVFIEL NHIKKCNTVR GVFVLEEFVP
1610 1620 1630 1640
EIKEVVSHKY KTPMAHEICY SVLCLFSYVA AVRSSEEDLR TPPRPVSS
Length:1,648
Mass (Da):183,329
Last modified:November 30, 2010 - v1
Checksum:i38DD014C09F9D81A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03011491 Genomic DNA No translation available.
RefSeqiXP_005631298.1, XM_005631241.2

Genome annotation databases

EnsembliENSCAFT00000013779; ENSCAFP00000012742; ENSCAFG00000008656
GeneIDi475982
KEGGicfa:475982

Similar proteinsi

Entry informationi

Entry nameiE2QTJ4_CANLF
AccessioniPrimary (citable) accession number: E2QTJ4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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