UniProtKB - E2QCY2 (E2QCY2_DROME)

BLAST

>tr|E2QCY2|E2QCY2_DROME FI16836p1 OS=Drosophila melanogaster OX=7227 GN=Dmel\CG3961 PE=1 SV=1
MSCCGQITSIRVPIELSNQSDVLKGPEQIHVSKFYKESKNGKFVSYITENVRTLYQTFRE
GAYASNNGPCLGWRETLTSPYQWINYDEALLRAKNFGAGMLALGARPKQLIGIYSQNRPE
WILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDDGKAAMLLEKAPRSLKI
IVAIKPIRQTTLERARSRGIQIFSFIDVEKLGAKGNHPEVPPTAEDLCTVCYTSGTTGNP
KGVMLTHGNVVAGVCSVILQMGDHRIRAGDVMVSFLPLAHMFERCCENGMYYVGGCVGFY
SGDIKELTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASGLKRGLFNMAMRAKEKEIAR
GVLRRNGCWDKLVFKKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTEC
TGAITLTVQGDHVPNHVGPPVSCNAVKLVDVPEMEYFANQNTGEVCVRGSNVFHGYYKDP
EKTAEAIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYV
NQVYVYGESLKSCIIAVVVPDTDVLKQWATENNVRGTLSVLCNNKNVKELIMNDMLNWGK
QSGLKSFEQVKDIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMYKHLD

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History
Entry version 74 (07 Nov 2018)
Sequence version 1 (30 Nov 2010)
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Protein

Submitted name:

FI16836p1

Gene

Dmel\CG3961

Organism

Drosophila melanogaster (Fruit fly)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Molecular functionⁱ

long-chain fatty acid-CoA ligase activity
Source: FlyBase
Inferred from sequence or structural similarityⁱ
- 22758915

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

long-chain fatty acid metabolic process
Source: FlyBase
Inferred from sequence or structural similarityⁱ
- 22758915

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	LigaseImported

Molecular function

LigaseImported

Enzyme and pathway databases

Reactomeⁱ	R-DME-2046105 Linoleic acid (LA) metabolism R-DME-2046106 alpha-linolenic acid (ALA) metabolism R-DME-75876 Synthesis of very long-chain fatty acyl-CoAs

Reactomeⁱ

R-DME-2046105 Linoleic acid (LA) metabolism
R-DME-2046106 alpha-linolenic acid (ALA) metabolism
R-DME-75876 Synthesis of very long-chain fatty acyl-CoAs

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: FI16836p1Imported
Gene namesⁱ	Name:Dmel\CG3961Imported Synonyms:ACSL1Imported, CG3961-RDImported ORF Names:CG3961Imported, Dmel_CG3961Imported
Organismⁱ	Drosophila melanogaster (Fruit fly)Imported
Taxonomic identifierⁱ	7227 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophila › Sophophora › melanogaster group › melanogaster subgroup
Proteomesⁱ	UP000000803 Componentⁱ: Chromosome 3L

Organism-specific databases

Drosophila genome database More...FlyBaseⁱ	FBgn0036821 CG3961

FlyBaseⁱ

FBgn0036821 CG3961

Expressionⁱ

Gene expression databases

Bgeeⁱ	FBgn0036821 Expressed in 37 organ(s), highest expression level in material anatomical entity

Bgeeⁱ

FBgn0036821 Expressed in 37 organ(s), highest expression level in material anatomical entity

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	79 – 520	AMP-bindingInterPro annotationAdd BLAST		442
Domainⁱ	529 – 571	AMP-binding_CInterPro annotationAdd BLAST		43

Phylogenomic databases

eggNOGⁱ	KOG1256 Eukaryota COG1022 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00690000101725
OMAⁱ	KNDIATQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G03G9

Family and domain databases

InterProⁱ	View protein in InterPro IPR025110 AMP-bd_C IPR020845 AMP-binding_CS IPR000873 AMP-dep_Synth/Lig
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00501 AMP-binding, 1 hit PF13193 AMP-binding_C, 1 hit
PROSITEⁱ	View protein in PROSITE PS00455 AMP_BINDING, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

E2QCY2-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MSCCGQITSI RVPIELSNQS DVLKGPEQIH VSKFYKESKN GKFVSYITEN 
        60         70         80         90        100
VRTLYQTFRE GAYASNNGPC LGWRETLTSP YQWINYDEAL LRAKNFGAGM 
       110        120        130        140        150
LALGARPKQL IGIYSQNRPE WILYEQGCYS FSLVVVPLYD TLGPDACAFI 
       160        170        180        190        200
IRQTDMQVVI VEDDGKAAML LEKAPRSLKI IVAIKPIRQT TLERARSRGI 
       210        220        230        240        250
QIFSFIDVEK LGAKGNHPEV PPTAEDLCTV CYTSGTTGNP KGVMLTHGNV 
       260        270        280        290        300
VAGVCSVILQ MGDHRIRAGD VMVSFLPLAH MFERCCENGM YYVGGCVGFY 
       310        320        330        340        350
SGDIKELTND LKMLKPTVMP AVPRLLNRVY DKIQNDISAS GLKRGLFNMA 
       360        370        380        390        400
MRAKEKEIAR GVLRRNGCWD KLVFKKVHQA FGGNLRLMVV GSAPLAGNVL 
       410        420        430        440        450
TFMRCALGCL VLEGYGQTEC TGAITLTVQG DHVPNHVGPP VSCNAVKLVD 
       460        470        480        490        500
VPEMEYFANQ NTGEVCVRGS NVFHGYYKDP EKTAEAIDSE GWHHTGDVGM 
       510        520        530        540        550
WLPNGTLRII DRRKHIFKLS QGEYIVPEKI ENIYTLSQYV NQVYVYGESL 
       560        570        580        590        600
KSCIIAVVVP DTDVLKQWAT ENNVRGTLSV LCNNKNVKEL IMNDMLNWGK 
       610        620        630        640        650
QSGLKSFEQV KDIYLHPDPF SVQNGLLTPT FKAKRPQLKS YFKPQLEDMY 

KHLD

Length:654

Mass (Da):73,033

Last modified:November 30, 2010 - v1

Checksum:ⁱ9FBCD4919C41C4C5

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q9VVT8	Q9VVT8_DROME	LD09909p LD09909p	Dmel\CG3961 ACSL1, CG3961-RA, CG3961, Dmel_CG3961	704	Annotation score:
M9PCX4	M9PCX4_DROME	Uncharacterized protein, isoform E Uncharacterized protein, isoform E, EC 6.2.1.3	Dmel\CG3961 ACSL1, CG3961, Dmel_CG3961	666	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE014296 Genomic DNA Translation: AAN11673.2 BT132918 mRNA Translation: AEW12890.1
NCBI Reference Sequences More...RefSeqⁱ	NP_730370.2, NM_168782.2
UniGeneⁱ	Dm.3546

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0302322; FBpp0291528; FBgn0036821
GeneIDⁱ	40056

Protein	Similar proteins		Species	Score	Length	Source
E2QCY2	Uncharacterized protein, isoform C		DROSI		654	UniRef100_E2QCY2

Protein	Similar proteins		Species	Score	Length	Source
E2QCY2	Uncharacterized protein, isoform E		DROME		666	UniRef90_M9PCX4
Uncharacterized protein, isoform B		DROSI		666
Uncharacterized protein (Fragment)		LUCCU		788
Uncharacterized protein		STOCA		666
Uncharacterized protein, isoform C		DROMO		666
+44

Protein	Similar proteins		Species	Score	Length	Source
E2QCY2	Uncharacterized protein		ANOCA		698	UniRef50_G1KB02
Uncharacterized protein		PHLPP		636
Putative acyl-coa synthetase		Nyssomyia neivai		689
long-chain-fatty-acid--CoA ligase 1-like		ICTPU		697
Acyl-CoA synthetase long chain family member 6		GASAC		687
+536

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE014296 Genomic DNA Translation: AAN11673.2 BT132918 mRNA Translation: AEW12890.1
RefSeqⁱ	NP_730370.2, NM_168782.2
UniGeneⁱ	Dm.3546

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0302322; FBpp0291528; FBgn0036821
GeneIDⁱ	40056

Organism-specific databases

FlyBaseⁱ	FBgn0036821 CG3961

FlyBaseⁱ

FBgn0036821 CG3961

Phylogenomic databases

eggNOGⁱ	KOG1256 Eukaryota COG1022 LUCA
GeneTreeⁱ	ENSGT00690000101725
OMAⁱ	KNDIATQ
OrthoDBⁱ	EOG091G03G9

Enzyme and pathway databases

Reactomeⁱ	R-DME-2046105 Linoleic acid (LA) metabolism R-DME-2046106 alpha-linolenic acid (ALA) metabolism R-DME-75876 Synthesis of very long-chain fatty acyl-CoAs

Reactomeⁱ

R-DME-2046105 Linoleic acid (LA) metabolism
R-DME-2046106 alpha-linolenic acid (ALA) metabolism
R-DME-75876 Synthesis of very long-chain fatty acyl-CoAs

Miscellaneous databases

GenomeRNAiⁱ	40056

GenomeRNAiⁱ

40056

Gene expression databases

Bgeeⁱ	FBgn0036821 Expressed in 37 organ(s), highest expression level in material anatomical entity

Bgeeⁱ

FBgn0036821 Expressed in 37 organ(s), highest expression level in material anatomical entity

Family and domain databases

InterProⁱ	View protein in InterPro IPR025110 AMP-bd_C IPR020845 AMP-binding_CS IPR000873 AMP-dep_Synth/Lig
Pfamⁱ	View protein in Pfam PF00501 AMP-binding, 1 hit PF13193 AMP-binding_C, 1 hit
PROSITEⁱ	View protein in PROSITE PS00455 AMP_BINDING, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E2QCY2_DROME
Accessionⁱ	E2QCY2Primary (citable) accession number: E2QCY2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 30, 2010
	Last sequence update:	November 30, 2010
	Last modified:	November 7, 2018
	This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - E2QCY2 (E2QCY2_DROME)

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FI16836p1

Dmel\CG3961

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence (1+)ⁱ

Computationally mapped potential isoform sequencesⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

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UniParc

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UniRef

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Annotation systems

Supporting data

UniProtKB - E2QCY2 (E2QCY2_DROME)

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FI16836p1

Dmel\CG3961

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Expressionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ