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Entry version 76 (12 Aug 2020)
Sequence version 1 (30 Nov 2010)
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Protein
Submitted name:

Jing, isoform H

Gene

jing

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Jing, isoform HImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:jingImported
Synonyms:1.28Imported, AEBP2Imported, CG9403Imported, CT9093Imported, Dmel\CG9397Imported, JingImported, l(2)01094Imported, l(2)22F3Imported
ORF Names:CG9397Imported, Dmel_CG9397Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0086655, jing

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0086655, Expressed in central nervous system and 65 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E2QC63, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E2QC63, DM

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E2QC63

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1214 – 1243C2H2-typeInterPro annotationAdd BLAST30

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 102DisorderedSequence analysisAdd BLAST102
Regioni150 – 180DisorderedSequence analysisAdd BLAST31
Regioni199 – 225DisorderedSequence analysisAdd BLAST27
Regioni250 – 360DisorderedSequence analysisAdd BLAST111
Regioni568 – 618DisorderedSequence analysisAdd BLAST51
Regioni633 – 669DisorderedSequence analysisAdd BLAST37
Regioni711 – 735DisorderedSequence analysisAdd BLAST25
Regioni776 – 806DisorderedSequence analysisAdd BLAST31
Regioni826 – 1096DisorderedSequence analysisAdd BLAST271
Regioni1242 – 1269DisorderedSequence analysisAdd BLAST28
Regioni1397 – 1486DisorderedSequence analysisAdd BLAST90

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi7 – 92PolarSequence analysisAdd BLAST86
Compositional biasi163 – 180PolarSequence analysisAdd BLAST18
Compositional biasi199 – 217PolarSequence analysisAdd BLAST19
Compositional biasi266 – 297PolarSequence analysisAdd BLAST32
Compositional biasi343 – 360Pro-richSequence analysisAdd BLAST18
Compositional biasi641 – 655PolarSequence analysisAdd BLAST15
Compositional biasi826 – 846PolarSequence analysisAdd BLAST21
Compositional biasi867 – 905PolarSequence analysisAdd BLAST39
Compositional biasi915 – 958PolarSequence analysisAdd BLAST44
Compositional biasi975 – 992PolarSequence analysisAdd BLAST18
Compositional biasi993 – 1018PolyampholyteSequence analysisAdd BLAST26
Compositional biasi1023 – 1077PolarSequence analysisAdd BLAST55
Compositional biasi1242 – 1256PolarSequence analysisAdd BLAST15
Compositional biasi1402 – 1430AcidicSequence analysisAdd BLAST29
Compositional biasi1434 – 1454PolarSequence analysisAdd BLAST21

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_246373_0_0_1

KEGG Orthology (KO)

More...
KOi
K17452

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E2QC63-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPHILGSAS GSSSTAAASP PTSSASQTPP SPAIHHSHLS QHNATSAMSK
60 70 80 90 100
PTTPQRHGNP SLLPTLQWPW NTSLGSTSTA VPAASANKNK RTAAGSGAAL
110 120 130 140 150
GLSGEGSCLT GGGAASAKKA RSDLPGSFDA SKRLKVAAME ESQTKITGFF
160 170 180 190 200
KSQMKPSPGG GKLSPQPGQQ SNPANTLTMS TPATTASLNK YFNILSQLKE
210 220 230 240 250
QKAQQQQQQQ QASKTLPTPA PVAPVPSAPP VAPVVVTPSP SLPVPALKKI
260 270 280 290 300
ERSNKQPAKI AQVAPNLRKT PSSGSSGSSS SSSSSSSNGS NTGKSPTKKH
310 320 330 340 350
VAIAPRTPEM KQQQQQGKAA MVYRPPVTST ALKQKQISPP APVAAHTPAP
360 370 380 390 400
APALNPTPAP ANPTLYQLPV QLPNLVQLPP QLAAAANIMQ LNNVAKAAVA
410 420 430 440 450
AAATNNAAAQ AAQAAQAAAA QYFLNGTVFK LQQVTTATTT TATTATAAAA
460 470 480 490 500
PAGNPFGLLN LATAGNPFGL PNANGQFPIE AIPGAGSYLH HQLLLARQNN
510 520 530 540 550
MSLNETMASN SCGNMNFVNP LNNQQVGLKD NKLYIVNSAE YLGYLMSLQI
560 570 580 590 600
ALNNQQHQQQ QIISATQPPP LAATNNNSTN TATQPPPLAA TNNTNSNTAN
610 620 630 640 650
NSTASNSINH NASNNLSNIN NTAIQPQRAI VKPPLHSSTQ PPPLVTISSM
660 670 680 690 700
PACSPAAASS PAAKRSLPAA KPYQKRLTAK GRVGTAPIIA TPTTPPPLVP
710 720 730 740 750
TSATKELGQL RKSTGTTGTP TGTPTPTPPL VSIAPSKLTP TLSVSKQGPT
760 770 780 790 800
MKLANSAPDL FDLVKNSKLV AKVSQPLTPL PFSSPSSSSN GSHGSHGMRS
810 820 830 840 850
SPALSTSNSC TLSAFSKIKV ETTELASQTG SLTSSSIPTI SLKPQSFAGQ
860 870 880 890 900
LPKREPESET DTLKHDLLPD CTNSNSNSNS CSSSTYSHSV SSAADLSLEA
910 920 930 940 950
STPAPSPSPS ASPSGLGSPS PAASNLSASS RRAASQTDML SELVTSSCIS
960 970 980 990 1000
SGGDDCSQAT DSPPMPALPL AKSEDATTPI STVSGGSSSG SSNYDEEDDK
1010 1020 1030 1040 1050
SVASLETHQT HKRLRDLPTP ESGIGGSLSN SESSNSIADA ISSKSASVGP
1060 1070 1080 1090 1100
PTTAASSASS SASDSNSLAS NAPSPASPED CSAAPSPACS ASTTGSIPPS
1110 1120 1130 1140 1150
TVVDIAMVEA TSKSLPKSAI SPILSQPKTI RFPAGAGASG KGGKRHDGVC
1160 1170 1180 1190 1200
YWDKCNKKHE SNSKLLDHMQ THHVNTQTGP FACLWVGCKV YNKESCSRRW
1210 1220 1230 1240 1250
LERHVLSHGG SKQFKCIVEG CGLRFGSQLA LQKHVNNHFN ATDNARESTS
1260 1270 1280 1290 1300
KRTSDPPVPK QLRKNGKKLR YRRQPFSARM FDFFDTGIME GLQHRLRQIS
1310 1320 1330 1340 1350
TLTNGAQAIE FQGQCMMRRR NSQGGYECFV RWSPREIISD EWLPECLNRT
1360 1370 1380 1390 1400
RQHTKVLHIK QMRPAEKTRV DSLLSTAFRL RYDSHLFADD YNVNEQQVGE
1410 1420 1430 1440 1450
ASGSDCDEDG DGDQEEEDLE DQDEDEEEDG SSSSRSASCE TVSSYQQVLS
1460 1470 1480
IAKLQMQQRR KHPRKPPKVT PPAREKLVPT DALVPI
Length:1,486
Mass (Da):155,258
Last modified:November 30, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8FB5F1BF0F8495D5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7KHG2JING_DROME
Zinc finger protein jing
jing rhumba, CG9397, CG9403
1,486Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8DY48A8DY48_DROME
Jing, isoform I
jing 1.28, AEBP2, CG9403, CT9093, Dmel\CG9397
1,744Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0C4DHC2A0A0C4DHC2_DROME
Jing, isoform J
jing 1.28, AEBP2, CG9403, CT9093, Dmel\CG9397
1,471Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAM68380.1

NCBI Reference Sequences

More...
RefSeqi
NP_001097199.1, NM_001103729.2
NP_995749.2, NM_206027.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0114364; FBpp0112913; FBgn0086655
FBtr0301636; FBpp0290850; FBgn0086655

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
35555

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG9397

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAM68380.1
RefSeqiNP_001097199.1, NM_001103729.2
NP_995749.2, NM_206027.3

3D structure databases

SMRiE2QC63
ModBaseiSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0114364; FBpp0112913; FBgn0086655
FBtr0301636; FBpp0290850; FBgn0086655
GeneIDi35555
KEGGidme:Dmel_CG9397

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
35555
FlyBaseiFBgn0086655, jing

Phylogenomic databases

HOGENOMiCLU_246373_0_0_1
KOiK17452

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
35555, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
35555

Gene expression databases

BgeeiFBgn0086655, Expressed in central nervous system and 65 other tissues
ExpressionAtlasiE2QC63, baseline and differential
GenevisibleiE2QC63, DM

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 3 hits
SUPFAMiSSF57667, SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE2QC63_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E2QC63
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: August 12, 2020
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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