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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Haemophilus influenzae (strain 10810)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHINF862964:G1GWT-1848-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:HIB_17650Imported
OrganismiHaemophilus influenzae (strain 10810)Imported
Taxonomic identifieri862964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000008964 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE1X875
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 87Arg_tRNA_synt_NInterPro annotationAdd BLAST87
Domaini460 – 577DALR_1InterPro annotationAdd BLAST118

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

E1X875-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQSILSDK IKQAMILAGA DQSCDALIRQ SGKPQFGDYQ ANGIMAAAKK
60 70 80 90 100
LGLNPREFAQ KVLDNAQLSD IAEKLEIAGP GFINIFLNPT WLTTEISAAL
110 120 130 140 150
SHKNLGIQAT NKQTVVIDYS SPNVAKEMHV GHLRSTIIGD AVTRTLEFLG
160 170 180 190 200
HNVIRANHVG DWGTQFGMLI AYLEKMQNEH ASEMELQDLE AFYREAKKHY
210 220 230 240 250
DEDEIFAEKA RNYVVKLQSG DEYCRTMWKR LVDITMQQNQ HNYDRLNVTL
260 270 280 290 300
TEKDVMGESL YNPMLPSIVE DLKKQGLAVE NDGALVVYLD EFKNKEGDPM
310 320 330 340 350
GVIVQKKDGG FLYTTTDIAA AKYRYETLKA NRALVFSDTR QSQHMQQAWL
360 370 380 390 400
ITRKAGYVPD SFSLEHKNFG MMLGKDGKPF KTRTGGTVKL ADLLDEAIER
410 420 430 440 450
ATVLINEKNT NLSNDEKEAV IEAVGIGAVK YADLSKNRTT DYVFDWDNML
460 470 480 490 500
SFEGNTAPYM QYAYTRIRSI FNKTDINSTA LLAAPLTIKD DKERTLAIKL
510 520 530 540 550
LQFEEAVQTV GKEGTPHVLC AYLYELAGIF SSFYEHCPIL NAEDESIKLS
560 570
RLKLALLTEK TLKQGLTLLG IKTVEKM
Length:577
Mass (Da):64,793
Last modified:November 30, 2010 - v1
Checksum:i9782E8BCE863E259
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312006 Genomic DNA Translation: CBW29950.1
RefSeqiWP_015702413.1, NC_016809.1

Genome annotation databases

EnsemblBacteriaiCBW29950; CBW29950; HIB_17650
KEGGihiu:HIB_17650
PATRICifig|862964.3.peg.1837

Similar proteinsi

Entry informationi

Entry nameiE1X875_HAEI1
AccessioniPrimary (citable) accession number: E1X875
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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