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UniProtKB - E1W4K8 (E1W4K8_HAEP3)

Entry version 40 (12 Aug 2020)
Sequence version 1 (30 Nov 2010)
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Protein

TraG-D_C domain-containing protein

Gene

PARA_11950

Organism
Haemophilus parainfluenzae (strain T3T1)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		HPAR862965:G1GWU-1222-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TraG-D_C domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:PARA_11950Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaemophilus parainfluenzae (strain T3T1)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri862965 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007052 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		862965.PARA_11950

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini505 – 632TraG-D_CInterPro annotationAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni710 – 749DisorderedSequence analysisAdd BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi723 – 749AcidicSequence analysisAdd BLAST27

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG3505, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_024857_0_0_6

Identification of Orthologs from Complete Genome Data

More...OMAi		HIYKHGV

Database of Orthologous Groups

More...OrthoDBi		246216at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR022503, Conj_coupling_TraG/TraD_PFGI-1
IPR022458, Conjugative_coupling_TraG/TraD
IPR027417, P-loop_NTPase
IPR032689, TraG-D_C

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12696, TraG-D_C, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR03754, conj_TOL_TraD, 1 hit
TIGR03743, SXT_TraD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E1W4K8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQKHVLEGL LRPPVEFFPA AVHGTCAFVC CGAPWSLALN PLIGYGLGAA 
        60         70         80         90        100
FAGMGVMRFR QGMEIVRYHR NLRRLPHYAL TSRQIPVSKK ALFLGRGFEW 
       110        120        130        140        150
EPKHTQRLYD CFSANGQIYW KNGKWFKAAR DYEKVHDNWL SRLTSMDSPL 
       160        170        180        190        200
NPVRPLPPVG GIPVMHGVEP NERDIMLPLG DRGGHTLVFG TTGVGKTRFA 
       210        220        230        240        250
EVLVTQDIHR GKTPEEREVV VFFDPKGDPD MLKRMYAEAK RAGRENEFYV 
       260        270        280        290        300
FHLGHPEISA RYNPVGRFGR ISEVAGRISG QLSGAGNSAA FKEFAWRFVN 
       310        320        330        340        350
IVSRALVEMG KRPDYVQISR FVQNIDALFL DYAKLHFDAI DKKIWPTLAS 
       360        370        380        390        400
VAANLDVKNL PFSMKDRPLI AVINQYILEN KIFDPVLEGL SSAVRYDKTY 
       410        420        430        440        450
FDKIVASLLP LLEKLTTGKT AELLSPDYTD IHDERPIFDW ESIIRKRGIV 
       460        470        480        490        500
YVGLDALSDA TVAAAVGNSM FADLVSMAGH IYKFGVDEGL PDVFKTKSKP 
       510        520        530        540        550
PKINLHCDEF NELMGDEFIP LINKGRGAGM QVTAYTQTLS DIEARIGSKA 
       560        570        580        590        600
KTGQTTGNFN TLLMFRVKEP ATAEFLTRQL NDVTIYQSMV TSSTTDNSNP 
       610        620        630        640        650
DDGKAFTSNT GERISEKMVP MLSPAHITNL PKGQAFALLE GSTLYKLRMP 
       660        670        680        690        700
LPAVDKDDVM PESLQELTAY MRKNYHISPN WWQSAFSDYA PSQDIATAFQ 
       710        720        730        740 
SMSLNRAPSH AGEEMLFGDV DTPVAEDMED EDIDQNDDTD EDDFDDTDD
Length:749
Mass (Da):83,815
Last modified:November 30, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i13F3B3D60F7C3D4A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
FQ312002 Genomic DNA Translation: CBW15300.1

NCBI Reference Sequences

More...RefSeqi		WP_014064983.1, NC_015964.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		CBW15300; CBW15300; PARA_11950

Database of genes from NCBI RefSeq genomes

More...GeneIDi		25058249

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hpr:PARA_11950

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|862965.3.peg.1196

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312002 Genomic DNA Translation: CBW15300.1
RefSeqiWP_014064983.1, NC_015964.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi862965.PARA_11950

Genome annotation databases

EnsemblBacteriaiCBW15300; CBW15300; PARA_11950
GeneIDi25058249
KEGGihpr:PARA_11950
PATRICifig|862965.3.peg.1196

Phylogenomic databases

eggNOGiCOG3505, Bacteria
HOGENOMiCLU_024857_0_0_6
OMAiHIYKHGV
OrthoDBi246216at2

Enzyme and pathway databases

BioCyciHPAR862965:G1GWU-1222-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR022503, Conj_coupling_TraG/TraD_PFGI-1
IPR022458, Conjugative_coupling_TraG/TraD
IPR027417, P-loop_NTPase
IPR032689, TraG-D_C
PfamiView protein in Pfam
PF12696, TraG-D_C, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR03754, conj_TOL_TraD, 1 hit
TIGR03743, SXT_TraD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE1W4K8_HAEP3
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1W4K8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: August 12, 2020
This is version 40 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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