UniProtKB - E1JIE2 (E1JIE2_DROME)
Protein
Submitted name:
Multiplexin, isoform L
Gene
Mp
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- carbohydrate binding Source: FlyBase
GO - Biological processi
- basement membrane organization Source: FlyBase
- cardiac muscle atrophy Source: FlyBase
- mitochondrion organization Source: FlyBase
- motor neuron axon guidance Source: FlyBase
- positive regulation of integrin-mediated signaling pathway Source: FlyBase
- skeletal muscle atrophy Source: FlyBase
Names & Taxonomyi
Protein namesi | Submitted name: Multiplexin, isoform LImported |
Gene namesi | Name:MpImported Synonyms:CG14822Imported, CG33171Imported, CG8645Imported, CG8647Imported, COL18A1Imported, CT14872Imported, Dmel\CG42543Imported, DmpImported, dmpImported, mpImported ORF Names:CG42543Imported, Dmel_CG42543Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0260660, Mp |
Subcellular locationi
Other locations
- collagen trimer Source: FlyBase
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5003147693 | 24 – 971 | Sequence analysisAdd BLAST | 948 |
Expressioni
Gene expression databases
Bgeei | FBgn0260660, Expressed in adult organism and 34 other tissues |
ExpressionAtlasi | E1JIE2, baseline and differential |
Genevisiblei | E1JIE2, DM |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 225 | LAM_G_DOMAINInterPro annotationAdd BLAST | 191 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 272 – 310 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 339 – 652 | DisorderedSequence analysisAdd BLAST | 314 | |
Regioni | 937 – 957 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 286 – 301 | Pro-richSequence analysisAdd BLAST | 16 | |
Compositional biasi | 391 – 405 | Pro-richSequence analysisAdd BLAST | 15 | |
Compositional biasi | 436 – 450 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 553 – 570 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 597 – 612 | Pro-richSequence analysisAdd BLAST | 16 |
Keywords - Domaini
CollagenARBA annotation, SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000172954 |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR008160, Collagen IPR010515, Collagenase_NC10/endostatin IPR013320, ConA-like_dom_sf IPR016187, CTDL_fold IPR001791, Laminin_G |
Pfami | View protein in Pfam PF01391, Collagen, 3 hits PF06482, Endostatin, 1 hit |
SMARTi | View protein in SMART SM00210, TSPN, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56436, SSF56436, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All
E1JIE2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRVLQGVMFA LAMICTLLVP VLGSFELVGQ SIKDALAEYT LTDIMNNNQF
60 70 80 90 100
AGIEFGEAED GFPAFRFLQT ADVKSPYRML LPEKLYEFAI LITFRQSSLK
110 120 130 140 150
GGYLFSVVNP LDTVVQLGVH LSPVVKNSYN VSLVYTQADQ NIGRKLASFG
160 170 180 190 200
VAHVPDKWNS IALQVLSDKV SFYYDCELRN TTLVTREPIE LVFDSASTLY
210 220 230 240 250
IGQAGSIIGG KFEGYLEKIN VYGNPDAINV TCMPPPKATI APTTADDGSI
260 270 280 290 300
FYEGSGENIL FEDSTEANIL SDDFWNTGDE GDSIRGPPGP PGPPGPKGET
310 320 330 340 350
APYPPFVETT SAGAKYTGEC TCNASDILEA IKDNESLRES LRGAPGTPGK
360 370 380 390 400
DGKPGTPGHT GATGVPGARG ARGSEGAQGL KGEPGVDGLP GVMGPPGPPG
410 420 430 440 450
PPGLPENYDE SLMVNSMGAF RGTTQPGAKG VPGEKGDAGQ KGERGDPGHK
460 470 480 490 500
GAHGPSGAKG EPGEPGTPGL PGLPGQVGQP GGLDGLASAN GTKGEKGEKG
510 520 530 540 550
EKGMRGRRGG TGATGPIGPP GKPGPMGDIG HSGRPGMTGP KGEMGPKGPK
560 570 580 590 600
GDSGGREGLK GDKGDRGQDG RDGLPGPPGL PSTGGGDGDS GGVQYIPMPG
610 620 630 640 650
PPGPPGPPGL PGLSISGPKG EPGVDSRSSF FGDASYYGRP EPPRQPGHSH
660 670 680 690 700
KHEETLGLVD GEEPYFSASS SNMNMKIVPG AVTFQNIDEM TKKSALNPPG
710 720 730 740 750
TLAYITEEEA LLVRVNKGWQ YIALGTLVPI ATPAPPTTVA PSMRFDLQSK
760 770 780 790 800
NLLNSPPPLL NTPTLRVAAL NEPSTGDLQG IRGADFACYR QGRRAGLLGT
810 820 830 840 850
FKAFLSSRVQ NLDTIVRPAD RDLPVVNTRG DVLFNSWKGI FNGQGGFFSQ
860 870 880 890 900
APRIYSFSGK NVMTDSTWPM KMVWHGSLPN GERSMDTYCD AWHSGDHLKG
910 920 930 940 950
SFASNLDGHK LLEQKRQSCD SKLIILCVEA LSQDRKRKKR EIGDGSSHGE
960 970
SESREFKTAD EYAAHLENLL L
Computationally mapped potential isoform sequencesi
There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE1JID9 | E1JID9_DROME | Multiplexin, isoform G | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,023 | Annotation score: | ||
E1JIE0 | E1JIE0_DROME | Multiplexin, isoform M | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,017 | Annotation score: | ||
E1JIE1 | E1JIE1_DROME | Multiplexin, isoform B | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,008 | Annotation score: | ||
E1JIE3 | E1JIE3_DROME | Multiplexin, isoform O | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,013 | Annotation score: | ||
X2JC42 | X2JC42_DROME | Multiplexin, isoform T | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,022 | Annotation score: | ||
X2JCL0 | X2JCL0_DROME | Multiplexin, isoform U | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 973 | Annotation score: | ||
Q86BH1 | Q86BH1_DROME | Multiplexin, isoform E | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 778 | Annotation score: | ||
E1JI49 | E1JI49_DROME | Multiplexin, isoform H | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 813 | Annotation score: | ||
E1JI52 | E1JI52_DROME | Multiplexin, isoform J | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 579 | Annotation score: | ||
E1JI50 | E1JI50_DROME | Multiplexin, isoform F | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 787 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: ACZ94634.1 |
RefSeqi | NP_001163363.1, NM_001169892.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0301113; FBpp0290335; FBgn0260660 |
GeneIDi | 38769 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: ACZ94634.1 |
RefSeqi | NP_001163363.1, NM_001169892.2 |
3D structure databases
SMRi | E1JIE2 |
ModBasei | Search... |
Genome annotation databases
EnsemblMetazoai | FBtr0301113; FBpp0290335; FBgn0260660 |
GeneIDi | 38769 |
Organism-specific databases
CTDi | 104327 |
FlyBasei | FBgn0260660, Mp |
Phylogenomic databases
GeneTreei | ENSGT00940000172954 |
Miscellaneous databases
BioGRID-ORCSi | 38769, 0 hits in 3 CRISPR screens |
GenomeRNAii | 38769 |
Gene expression databases
Bgeei | FBgn0260660, Expressed in adult organism and 34 other tissues |
ExpressionAtlasi | E1JIE2, baseline and differential |
Genevisiblei | E1JIE2, DM |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR008160, Collagen IPR010515, Collagenase_NC10/endostatin IPR013320, ConA-like_dom_sf IPR016187, CTDL_fold IPR001791, Laminin_G |
Pfami | View protein in Pfam PF01391, Collagen, 3 hits PF06482, Endostatin, 1 hit |
SMARTi | View protein in SMART SM00210, TSPN, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56436, SSF56436, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E1JIE2_DROME | |
Accessioni | E1JIE2Primary (citable) accession number: E1JIE2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 30, 2010 |
Last sequence update: | November 30, 2010 | |
Last modified: | February 10, 2021 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |