UniProtKB - E1JI52 (E1JI52_DROME)
Protein
Submitted name:
Multiplexin, isoform J
Gene
Mp
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- carbohydrate binding Source: FlyBase
GO - Biological processi
- basement membrane organization Source: FlyBase
- cardiac muscle atrophy Source: FlyBase
- mitochondrion organization Source: FlyBase
- motor neuron axon guidance Source: FlyBase
- positive regulation of integrin-mediated signaling pathway Source: FlyBase
- skeletal muscle atrophy Source: FlyBase
Names & Taxonomyi
Protein namesi | Submitted name: Multiplexin, isoform JImported |
Gene namesi | Name:MpImported Synonyms:CG14822Imported, CG33171Imported, CG8645Imported, CG8647Imported, COL18A1Imported, CT14872Imported, Dmel\CG42543Imported, DmpImported, dmpImported, mpImported ORF Names:CG42543Imported, Dmel_CG42543Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0260660, Mp |
Subcellular locationi
Other locations
- collagen trimer Source: FlyBase
Expressioni
Gene expression databases
Bgeei | FBgn0260660, Expressed in adult organism and 34 other tissues |
ExpressionAtlasi | E1JI52, baseline and differential |
Genevisiblei | E1JI52, DM |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 369 – 537 | EndostatinInterPro annotationAdd BLAST | 169 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 260 | DisorderedSequence analysisAdd BLAST | 260 | |
Regioni | 545 – 565 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 44 – 58 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 161 – 178 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 205 – 220 | Pro-richSequence analysisAdd BLAST | 16 |
Keywords - Domaini
CollagenARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000172954 |
HOGENOMi | CLU_004003_1_0_1 |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR008160, Collagen IPR010515, Collagenase_NC10/endostatin IPR016187, CTDL_fold |
Pfami | View protein in Pfam PF01391, Collagen, 2 hits PF06482, Endostatin, 1 hit |
SUPFAMi | SSF56436, SSF56436, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All
E1JI52-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGPPGPPGPP GLPENYDESL MVNSMGAFRG TTQPGAKGVP GEKGDAGQKG
60 70 80 90 100
ERGDPGHKGA HGPSGAKGEP GEPGTPGLPG LPGQVGQPGG LDGLASANGT
110 120 130 140 150
KGEKGEKGEK GMRGRRGGTG ATGPIGPPGK PGPMGDIGHS GRPGMTGPKG
160 170 180 190 200
EMGPKGPKGD SGGREGLKGD KGDRGQDGRD GLPGPPGLPS TGGGDGDSGG
210 220 230 240 250
VQYIPMPGPP GPPGPPGLPG LSISGPKGEP GVDSRSSFFG DASYYGRPEP
260 270 280 290 300
PRQPGHSHKH EETLGLVDGE EPYFSASSSN MNMKIVPGAV TFQNIDEMTK
310 320 330 340 350
KSALNPPGTL AYITEEEALL VRVNKGWQYI ALGTLVPIAT PAPPTTVAPS
360 370 380 390 400
MRFDLQSKNL LNSPPPLLNT PTLRVAALNE PSTGDLQGIR GADFACYRQG
410 420 430 440 450
RRAGLLGTFK AFLSSRVQNL DTIVRPADRD LPVVNTRGDV LFNSWKGIFN
460 470 480 490 500
GQGGFFSQAP RIYSFSGKNV MTDSTWPMKM VWHGSLPNGE RSMDTYCDAW
510 520 530 540 550
HSGDHLKGSF ASNLDGHKLL EQKRQSCDSK LIILCVEALS QDRKRKKREI
560 570
GDGSSHGESE SREFKTADEY AAHLENLLL
Computationally mapped potential isoform sequencesi
There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE1JID9 | E1JID9_DROME | Multiplexin, isoform G | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,023 | Annotation score: | ||
E1JIE0 | E1JIE0_DROME | Multiplexin, isoform M | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,017 | Annotation score: | ||
E1JIE1 | E1JIE1_DROME | Multiplexin, isoform B | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,008 | Annotation score: | ||
E1JIE2 | E1JIE2_DROME | Multiplexin, isoform L | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 971 | Annotation score: | ||
E1JIE3 | E1JIE3_DROME | Multiplexin, isoform O | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,013 | Annotation score: | ||
X2JC42 | X2JC42_DROME | Multiplexin, isoform T | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 1,022 | Annotation score: | ||
X2JCL0 | X2JCL0_DROME | Multiplexin, isoform U | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 973 | Annotation score: | ||
Q86BH1 | Q86BH1_DROME | Multiplexin, isoform E | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 778 | Annotation score: | ||
E1JI49 | E1JI49_DROME | Multiplexin, isoform H | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 813 | Annotation score: | ||
E1JI50 | E1JI50_DROME | Multiplexin, isoform F | Mp CG14822, CG33171, CG8645, CG8647, COL18A1 | 787 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: ACZ94632.1 |
RefSeqi | NP_001163361.1, NM_001169890.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0301111; FBpp0290333; FBgn0260660 |
GeneIDi | 38769 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: ACZ94632.1 |
RefSeqi | NP_001163361.1, NM_001169890.2 |
3D structure databases
SMRi | E1JI52 |
ModBasei | Search... |
Genome annotation databases
EnsemblMetazoai | FBtr0301111; FBpp0290333; FBgn0260660 |
GeneIDi | 38769 |
Organism-specific databases
CTDi | 104327 |
FlyBasei | FBgn0260660, Mp |
Phylogenomic databases
GeneTreei | ENSGT00940000172954 |
HOGENOMi | CLU_004003_1_0_1 |
Miscellaneous databases
BioGRID-ORCSi | 38769, 0 hits in 3 CRISPR screens |
GenomeRNAii | 38769 |
Gene expression databases
Bgeei | FBgn0260660, Expressed in adult organism and 34 other tissues |
ExpressionAtlasi | E1JI52, baseline and differential |
Genevisiblei | E1JI52, DM |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR008160, Collagen IPR010515, Collagenase_NC10/endostatin IPR016187, CTDL_fold |
Pfami | View protein in Pfam PF01391, Collagen, 2 hits PF06482, Endostatin, 1 hit |
SUPFAMi | SSF56436, SSF56436, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E1JI52_DROME | |
Accessioni | E1JI52Primary (citable) accession number: E1JI52 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 30, 2010 |
Last sequence update: | November 30, 2010 | |
Last modified: | February 10, 2021 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |