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Entry version 93 (26 Feb 2020)
Sequence version 1 (30 Nov 2010)
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Protein
Submitted name:

Starry night, isoform B

Gene

stan

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer
LigandCalciumSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Starry night, isoform BImported
Submitted name:
Starry night, isoform DImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:stanImported
Synonyms:CT20776Imported, Dmel\CG11895Imported, FlamImported, FmiImported, fmiImported, STANImported, StanImported
ORF Names:CG11895Imported, Dmel_CG11895Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0024836 stan

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2817 – 2837HelicalSequence analysisAdd BLAST21
Transmembranei2849 – 2868HelicalSequence analysisAdd BLAST20
Transmembranei2888 – 2908HelicalSequence analysisAdd BLAST21
Transmembranei2920 – 2940HelicalSequence analysisAdd BLAST21
Transmembranei2960 – 2980HelicalSequence analysisAdd BLAST21
Transmembranei3001 – 3023HelicalSequence analysisAdd BLAST23
Transmembranei3029 – 3052HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501508869130 – 3574Sequence analysisAdd BLAST3545

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi1508 ↔ 1517PROSITE-ProRule annotation
Disulfide bondi1782 ↔ 1791PROSITE-ProRule annotation
Disulfide bondi1969 ↔ 1979PROSITE-ProRule annotation
Disulfide bondi1990 ↔ 1999PROSITE-ProRule annotation
Disulfide bondi2095 ↔ 2107PROSITE-ProRule annotation
Disulfide bondi2097 ↔ 2114PROSITE-ProRule annotation
Disulfide bondi2116 ↔ 2125PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0024836 Expressed in eye disc (Drosophila) and 25 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E1JH30 differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E1JH30

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1482 – 1518EGF-likeInterPro annotationAdd BLAST37
Domaini1556 – 1753LAM_G_DOMAINInterPro annotationAdd BLAST198
Domaini1756 – 1792EGF-likeInterPro annotationAdd BLAST37
Domaini1796 – 1963LAM_G_DOMAINInterPro annotationAdd BLAST168
Domaini1965 – 2000EGF-likeInterPro annotationAdd BLAST36
Domaini2095 – 2142Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2115 – 2201G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST87
Domaini2744 – 2802GPSInterPro annotationAdd BLAST59
Domaini2812 – 3053G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST242

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2553 – 2582DisorderedSequence analysisAdd BLAST30
Regioni2610 – 2635DisorderedSequence analysisAdd BLAST26
Regioni2654 – 2684DisorderedSequence analysisAdd BLAST31
Regioni3111 – 3225DisorderedSequence analysisAdd BLAST115
Regioni3343 – 3377DisorderedSequence analysisAdd BLAST35
Regioni3458 – 3486DisorderedSequence analysisAdd BLAST29
Regioni3499 – 3574DisorderedSequence analysisAdd BLAST76

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2560 – 2582PolarSequence analysisAdd BLAST23
Compositional biasi2665 – 2679PolarSequence analysisAdd BLAST15
Compositional biasi3111 – 3164PolarSequence analysisAdd BLAST54
Compositional biasi3165 – 3187PolyampholyteSequence analysisAdd BLAST23
Compositional biasi3195 – 3210PolyampholyteSequence analysisAdd BLAST16
Compositional biasi3211 – 3225PolarSequence analysisAdd BLAST15
Compositional biasi3472 – 3486PolyampholyteSequence analysisAdd BLAST15
Compositional biasi3536 – 3553PolarSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, Laminin EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4289 Eukaryota
ENOG410XTGH LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000158_1_0_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.1240.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR013320 ConA-like_dom_sf
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR032471 GAIN_dom_N
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR000832 GPCR_2_secretin-like
IPR000203 GPS
IPR002049 Laminin_EGF
IPR001791 Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00002 7tm_2, 1 hit
PF00028 Cadherin, 8 hits
PF00008 EGF, 2 hits
PF16489 GAIN, 1 hit
PF00053 Laminin_EGF, 1 hit
PF02210 Laminin_G_2, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205 CADHERIN
PR00249 GPCRSECRETIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112 CA, 8 hits
SM00181 EGF, 5 hits
SM00179 EGF_CA, 2 hits
SM00180 EGF_Lam, 1 hit
SM00303 GPS, 1 hit
SM00008 HormR, 1 hit
SM00282 LamG, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313 SSF49313, 9 hits
SSF49899 SSF49899, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00232 CADHERIN_1, 5 hits
PS00022 EGF_1, 3 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 3 hits
PS01248 EGF_LAM_1, 1 hit
PS50027 EGF_LAM_2, 1 hit
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS50025 LAM_G_DOMAIN, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

E1JH30-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQTREFPQRP LGLLLVLLVV LLQSSLIKSY LIIVHEDTPP GTVIFNASVY
60 70 80 90 100
KLGSERHYKI NAHKSANFVH HLVSVNHKDG QIQLRKALKC DGIYYPNLFT
110 120 130 140 150
FYVDSTSNRL RSIDYYSLPV RIFVSGHSCN EDRRIEQELH HHHYEEEDNT
160 170 180 190 200
GYSKRRRRRS TQEMIQLNGN QLEEVFRQNS TEFRAGDLIF GDSFDNEMRH
210 220 230 240 250
RILSRKRRAV GSPDPLHLQP ALHRRISDAK QWISETYASY AIHTTDKWNQ
260 270 280 290 300
ICLRRSQFIN SLNAFLPRSV CQHCKVSFLD VNDERFAIEH QSRDLVASRD
310 320 330 340 350
VCIAESMWKV SITFNIRCDR RDIVDSDHRL KIVYHHQEFN DTDIARRVRR
360 370 380 390 400
ELRNQSPYFE QALYVASVLE EQPAGAAVTT VRARDPEDSP VVYSMVSLLD
410 420 430 440 450
SRSQSLFKVD SRTGVVTTSA SLDRELMDVH YFRVVATDDS FPPRSGTTTL
460 470 480 490 500
QVNVLDCNDH SPTFEAEQFE ASIREGATVG STVITLRATD QDIGKNAEIE
510 520 530 540 550
YGIEAVTDGA GLAQDQEMPI FRIDSRSGVI STRSSLDRET SDSYHLLVTA
560 570 580 590 600
ADLASAQSER RTATASVQVK VLDDNDNYPQ FSERTYTVQV PEDQWGGTED
610 620 630 640 650
NTVAHIRATD ADQGNNAAIR YAIIGGNTQS QFSIDSMSGD VSLVKPLDYE
660 670 680 690 700
SVRSYRLVIR AQDGGSPSRS NTTQLLVNVI DANDNAPRFY TSQFQESVLE
710 720 730 740 750
NVPVGYNIIR VQAYDSDEGA NAEITYSISE RDDNFPLAVD PRTGWVQTIK
760 770 780 790 800
PLDREEQGRF AFQVVAKDGG VPPKSASSSV VITVQDVNDN DPAFNPKYYE
810 820 830 840 850
ANVGEDQPPG TPVTTVTATD PDEDSRLHYE ITTGNTRGRF AITSQNGRGL
860 870 880 890 900
ITIAQSLDYK QEKRFLLTVA ATDSGGRSDT ATVHINITDA NNFAPIFENA
910 920 930 940 950
PYSASVFEDA PVGTTVLVVS ATDSDVGVNA QITYSLNEES INGLGSPDPF
960 970 980 990 1000
SINPQTGAIV TNAPLDRETT SGYLLTVTAK DGGNPSLSDT TDVEIGVTDV
1010 1020 1030 1040 1050
NDNAPAFKSP LYQASILEDA LVGTSVIQVA ASDPDVGLNG RIKYLLSDRD
1060 1070 1080 1090 1100
IEDGSFVIDP TSGTIRTNKG LDRESVAVFH LTAIAVDKGS PPLSSTVEVQ
1110 1120 1130 1140 1150
IRLEDVNDSP PTFASDKITL YVPENSPVGS VVGEIHAHDP DEGVNAVVHY
1160 1170 1180 1190 1200
SIIGGDDSNA FSLVTRPGSE RAQLLTMTEL DYESTRKRFE LVVRAASPPL
1210 1220 1230 1240 1250
RNDAHIEILV TDVNDNAPVL RDFQVIFNNF RDHFPSGEIG RIPAFDADVS
1260 1270 1280 1290 1300
DKLHYRILSG NNANLLRLNS SSGGLVLSPQ LNTNVPKFAT MEVSVSDGIN
1310 1320 1330 1340 1350
EAKAIMQLSV RLITEDMLFN SVTVRLNEMT EEAFLSPLLN FFLDGLAAII
1360 1370 1380 1390 1400
PCPKEHIFVF SIQDDTDVSS RILNVSFSAR RPDVSHEEFY TPQYLQERVY
1410 1420 1430 1440 1450
LNRAILARLA TVEVLPFDDN LCVREPCLNF EECLTVLKFG NASEFIHSDT
1460 1470 1480 1490 1500
VLFRPIYPVN TFACSCPEGF TGSKEHYLCD TEVDLCYSDP CQNGGTCVRR
1510 1520 1530 1540 1550
EGGYTCVCPS THTGQNCETG VGHLRPCPSE TCEGGLSCLS NYPSSQPPPY
1560 1570 1580 1590 1600
TATCELRARA FGRNSFLTFE SLKQRHRFNL KLRFATVQEN GLLLYNGRYN
1610 1620 1630 1640 1650
ELHDFIALEI HEGHVSFSFS LGDHSERISV IQEAKVSDGK WHQVEVVYLN
1660 1670 1680 1690 1700
RSVTLVLDNC DTAIALSGQL GDRWSCANRT TLKLDKRCSL LTETCHRFLD
1710 1720 1730 1740 1750
LTGPLQVGGL PRIPAHFPVT NRDFVGCISD LRIDDRFVDL NSYVADNGTL
1760 1770 1780 1790 1800
AGCPQKAPLC QSEPCFNGGT CREGWGTYSC ECPEGYAGNS CQDNIPAPWR
1810 1820 1830 1840 1850
FSGDGSLSFN PLLRPIQLPW TTSFSLRTRQ KEAFLLQIQI GQNSSAAVCL
1860 1870 1880 1890 1900
RQGVLYYIFD GEPMYLAGAF LSDGEWHRVE IRWQQGSEIH FSVDYGQRSG
1910 1920 1930 1940 1950
SVPMSQKVQG LYVGKIVMGS PDGSIGAVPE ASPFEGCIQD VRIGAGQSVL
1960 1970 1980 1990 2000
SRPTIRENVE DGCESRAQCP DHCPNHSSCQ SSWDLSTCEC DSGYVGTDCA
2010 2020 2030 2040 2050
PICTVRPCAS GVCRANTSLP RGYDCECNSS SRHGDYCEKE LQQPCPGGWW
2060 2070 2080 2090 2100
GERVCGPCRC DLAQGYHPDC NKTTGQCYCK TNHYQPPNET ACLSCDCYSI
2110 2120 2130 2140 2150
GSFSGACNPL TGQCECREGV IGRRCDSCSN PYAEVTLSGC EVVYDACPRS
2160 2170 2180 2190 2200
FAGGVWWPRT PLGGVAIEGC PPPARGKGQR SCDVQSGSWN TPDMYNCTSE
2210 2220 2230 2240 2250
PFVELRRQLS QLEKLELELN SFVAIKMAEQ LRKACEAVDR RGASKDQKIS
2260 2270 2280 2290 2300
GNGRPNRRYK MESSFLLSNG GNVWSHELEM DYLSDELKFT HDRLYGADLL
2310 2320 2330 2340 2350
VTEGLLQELI NYELMQSGLN LSHSQDKYFI KNLVDAASVI LDRKYEAEWR
2360 2370 2380 2390 2400
RATELIQRGP DDLVDAFNKY LVVLARSQHD TYTSPFEIVQ PNMALGLDIV
2410 2420 2430 2440 2450
TTESLFGYEP EQLSEYHRSK YLKPNAFTTE SVVLPDTSGF LQHSARQRPV
2460 2470 2480 2490 2500
ISFPKYNNYI LDRRKFDQHT KVLVPLEMLG ITPPESDEIS QSGRRGSSHD
2510 2520 2530 2540 2550
HRAIVAYAQY KDVGQLLPDL YDETITRRWG VDVELATPIL SLQILVPSME
2560 2570 2580 2590 2600
REQETQRLEI PSRKIFSSSS PSSSSSSGST EQQFVEVFDV PKAPTSSSEQ
2610 2620 2630 2640 2650
QIEDIRITAH EIPPPVSSVE QQEASSDEDG EEREPHIRLN LDDIEFHGNS
2660 2670 2680 2690 2700
GEEVISPDSP EMLNPNYEGV SSTGSDEQPK GENEAVYRDR RLVKRQVEIT
2710 2720 2730 2740 2750
YPSEQMQQTE QVVYRSLGSP HLAQPIKLQM WLDVDSARFG PRSNPQCVRW
2760 2770 2780 2790 2800
NSFTNQWTRL GCQTEIPDFD GDFNPAAQQA ILVNCSCTHI SSYAVIVDVI
2810 2820 2830 2840 2850
DPEDIPEPSL LVQITSYSAF LVSLPLLLGV LLALALLRGQ QTNSNTIHQN
2860 2870 2880 2890 2900
IVLCVFCAEL LFFVGMQSRR QLLESEFPCK LTAICLHYFW LAAFAWTTVD
2910 2920 2930 2940 2950
CVHLYRMLTE MRDINHGPMG FYFAMGYGAP AIVVGLSVGV RAHEYGNSLF
2960 2970 2980 2990 3000
CWLSVYEPVV WWLVGPIAGM SVVNLLILFV SVKAAFTLKD HVLGFGNLRT
3010 3020 3030 3040 3050
LLWLSVVSLP LMGVMWVLAV LAASEHSQLL SLLLSGVVLL HALFCLIGYC
3060 3070 3080 3090 3100
IINKRVRENL QRTCLRCMGR KVPLLDSSMV VSNSSHNVNA AARPSNFLAS
3110 3120 3130 3140 3150
GYDTTTRRNI GISASSTTSR STAKTSSSPY SDGQLRQTST STSNYNSASD
3160 3170 3180 3190 3200
APSFLRGFES STTGRSRGGE EKPSRRQRKD SDSGSETDGR SLELASSHSS
3210 3220 3230 3240 3250
DDDESRTARS SGTHRSTAVS STPAYLPNIT EHVQATTPPE LNVVQSPQLF
3260 3270 3280 3290 3300
PSVNKPVYAP RWSSQLPDAY LQSPPNIGRW SQDTGSDNEH VHGQAKMTIS
3310 3320 3330 3340 3350
PNPLPNPDLT DTSYLQQHHN KINMPPSILE NIRDAREGYE DSLYGRRGEY
3360 3370 3380 3390 3400
PDKYGSYKPP SHYGSEKDYP GGGSGSQTIG HMRSFHPDAA YLSDNIYDKQ
3410 3420 3430 3440 3450
RTLGSGYLGA KSESPYLSKD RITPDIYGSR DGHYSLKRQP AYATDSLHSV
3460 3470 3480 3490 3500
HSLLKNDYHQ QQQQQQQHHL QDRLSEGSDK NGYHFPYTAE EDHLPARKLS
3510 3520 3530 3540 3550
HTQPPSLHGS QLMQPPGVGL VNDVNNPGLM GRHTLNGGSR HSSRASSPPS
3560 3570
TMVAPMQPLG PLTSITDTDS EAEY
Length:3,574
Mass (Da):396,549
Last modified:November 30, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i300AA4A28BC83D83
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9V5N8STAN_DROME
Protocadherin-like wing polarity pr...
stan fmi, CG11895
3,579Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4JD63A0A0B4JD63_DROME
Starry night, isoform C
stan CT20776, Dmel\CG11895, Flam, Fmi, fmi
3,579Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4LG27A0A0B4LG27_DROME
Starry night, isoform G
stan CT20776, Dmel\CG11895, Flam, Fmi, fmi
3,603Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4K6X2A0A0B4K6X2_DROME
Starry night, isoform E
stan CT20776, Dmel\CG11895, Flam, Fmi, fmi
3,578Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KER2A0A0B4KER2_DROME
Starry night, isoform F
stan CT20776, Dmel\CG11895, Flam, Fmi, fmi
3,648Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: ACZ94388.1
AE013599 Genomic DNA Translation: AFH08011.1

NCBI Reference Sequences

More...
RefSeqi
NP_001163113.1, NM_001169642.1
NP_001246257.1, NM_001259328.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0300578; FBpp0289805; FBgn0024836
FBtr0304899; FBpp0293438; FBgn0024836

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
36125

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: ACZ94388.1
AE013599 Genomic DNA Translation: AFH08011.1
RefSeqiNP_001163113.1, NM_001169642.1
NP_001246257.1, NM_001259328.2

3D structure databases

SMRiE1JH30
ModBaseiSearch...

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

Genome annotation databases

EnsemblMetazoaiFBtr0300578; FBpp0289805; FBgn0024836
FBtr0304899; FBpp0293438; FBgn0024836
GeneIDi36125

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
36125
FlyBaseiFBgn0024836 stan

Phylogenomic databases

eggNOGiKOG4289 Eukaryota
ENOG410XTGH LUCA
HOGENOMiCLU_000158_1_0_1

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
36125

Gene expression databases

BgeeiFBgn0024836 Expressed in eye disc (Drosophila) and 25 other tissues
ExpressionAtlasiE1JH30 differential

Family and domain databases

Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR013320 ConA-like_dom_sf
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR032471 GAIN_dom_N
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR000832 GPCR_2_secretin-like
IPR000203 GPS
IPR002049 Laminin_EGF
IPR001791 Laminin_G
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00028 Cadherin, 8 hits
PF00008 EGF, 2 hits
PF16489 GAIN, 1 hit
PF00053 Laminin_EGF, 1 hit
PF02210 Laminin_G_2, 2 hits
PRINTSiPR00205 CADHERIN
PR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00112 CA, 8 hits
SM00181 EGF, 5 hits
SM00179 EGF_CA, 2 hits
SM00180 EGF_Lam, 1 hit
SM00303 GPS, 1 hit
SM00008 HormR, 1 hit
SM00282 LamG, 2 hits
SUPFAMiSSF49313 SSF49313, 9 hits
SSF49899 SSF49899, 2 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 5 hits
PS00022 EGF_1, 3 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 3 hits
PS01248 EGF_LAM_1, 1 hit
PS50027 EGF_LAM_2, 1 hit
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS50025 LAM_G_DOMAIN, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE1JH30_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1JH30
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: February 26, 2020
This is version 93 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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