UniProtKB - E1BNQ3 (E1BNQ3_BOVIN)
Protein
Ras-related protein Rap-2
Gene
RAP2A
Organism
Bos taurus (Bovine)
Status
Functioni
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.UniRule annotation
Catalytic activityi
- EC:3.6.5.2ARBA annotation
GO - Molecular functioni
- GTPase activity Source: UniProtKB-UniRule
- GTP binding Source: UniProtKB-UniRule
GO - Biological processi
- positive regulation of protein autophosphorylation Source: UniProtKB-UniRule
- Rap protein signal transduction Source: UniProtKB-UniRule
Keywordsi
Ligand | GTP-bindingUniRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Ras-related protein Rap-2UniRule annotation |
Gene namesi | Name:RAP2AImported |
Organismi | Bos taurus (Bovine)Imported |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:33719, RAP2A |
Subcellular locationi
Endosome
- Endosome membrane ARBA annotation; Lipid-anchor ARBA annotation; Cytoplasmic side ARBA annotation
- Recycling endosome membrane UniRule annotationARBA annotation; Lipid-anchor UniRule annotationARBA annotation; Cytoplasmic side UniRule annotationARBA annotation
Endosome
- recycling endosome membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
EndosomeUniRule annotationARBA annotation, MembraneUniRule annotationPTM / Processingi
Post-translational modificationi
Palmitoylated.UniRule annotation
Keywords - PTMi
Lipoprotein, MethylationUniRule annotation, PalmitateUniRule annotationARBA annotation, PrenylationUniRule annotationProteomic databases
PaxDbi | E1BNQ3 |
PRIDEi | E1BNQ3 |
Expressioni
Gene expression databases
Bgeei | ENSBTAG00000020412, Expressed in conceptus and 18 other tissues |
ExpressionAtlasi | E1BNQ3, baseline |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0395, Eukaryota |
GeneTreei | ENSGT00940000160594 |
HOGENOMi | CLU_041217_9_8_1 |
InParanoidi | E1BNQ3 |
OMAi | IEDCFRT |
OrthoDBi | 1353024at2759 |
TreeFami | TF313014 |
Family and domain databases
CDDi | cd04176, Rap2, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR041840, Rap2 IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase IPR020849, Small_GTPase_Ras-type |
PANTHERi | PTHR24070, PTHR24070, 1 hit |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51421, RAS, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
E1BNQ3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MREYKVVVLG SGGVGKSALT VQFVTGTFIE KYDPTIEDFY RKEIEVDSSP
60 70 80 90 100
SVLEILDTAG TEQFASMRDL YIKNGQGFIL VYSLVNQQSF QDIKPMRDQI
110 120 130 140 150
IRVKRYEKVP VILVGNKVDL ESEREVSSNE GRALAEEWGC PFMETSAKSK
160 170 180
TMVDELFAEI VRQMNYAAQP DKDDPCCSAC NIQ
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q1MGL7 | A0A3Q1MGL7_BOVIN | Ras-related protein Rap-2 | RAP2A | 231 | Annotation score: |
Sequence databases
RefSeqi | NP_001179871.1, NM_001192942.1 |
Genome annotation databases
Ensembli | ENSBTAT00000027204; ENSBTAP00000027204; ENSBTAG00000020412 |
GeneIDi | 522707 |
KEGGi | bta:522707 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | NP_001179871.1, NM_001192942.1 |
3D structure databases
SMRi | E1BNQ3 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9913.ENSBTAP00000027204 |
Proteomic databases
PaxDbi | E1BNQ3 |
PRIDEi | E1BNQ3 |
Genome annotation databases
Ensembli | ENSBTAT00000027204; ENSBTAP00000027204; ENSBTAG00000020412 |
GeneIDi | 522707 |
KEGGi | bta:522707 |
Organism-specific databases
CTDi | 5911 |
VGNCi | VGNC:33719, RAP2A |
Phylogenomic databases
eggNOGi | KOG0395, Eukaryota |
GeneTreei | ENSGT00940000160594 |
HOGENOMi | CLU_041217_9_8_1 |
InParanoidi | E1BNQ3 |
OMAi | IEDCFRT |
OrthoDBi | 1353024at2759 |
TreeFami | TF313014 |
Gene expression databases
Bgeei | ENSBTAG00000020412, Expressed in conceptus and 18 other tissues |
ExpressionAtlasi | E1BNQ3, baseline |
Family and domain databases
CDDi | cd04176, Rap2, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR041840, Rap2 IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase IPR020849, Small_GTPase_Ras-type |
PANTHERi | PTHR24070, PTHR24070, 1 hit |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51421, RAS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E1BNQ3_BOVIN | |
Accessioni | E1BNQ3Primary (citable) accession number: E1BNQ3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 2, 2010 |
Last sequence update: | November 2, 2010 | |
Last modified: | December 2, 2020 | |
This is version 71 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |