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Entry version 52 (07 Oct 2020)
Sequence version 3 (09 Dec 2015)
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Protein

Periaxin

Gene

PRX

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the maintenance of the peripheral myelin sheath that is essential for normal transmission of nerve impulses and normal perception of sensory stimuli. Required for normal transport of MBP mRNA from the perinuclear to the paranodal regions. Required for normal remyelination after nerve injury. Required for normal elongation of Schwann cells and normal length of the internodes between the nodes of Ranvier. The demyelinated nodes of Ranvier permit saltatory transmission of nerve impulses; shorter internodes cause slower transmission of nerve impulses. Required for the formation of appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane; the Schwann cell cytoplasm is restricted to regions between these appositions. Required for the formation of Cajal bands and of Schmidt-Lanterman incisures that correspond to short, cytoplasm-filled regions on myelinated nerves. Recruits DRP2 to the Schwann cell plasma membrane. Required for normal protein composition of the eye lens fiber cell plasma membrane and normal eye lens fiber cell morphology.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PeriaxinCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRX
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000321980 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000009136 Componenti: Chromosome 18

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:33430, PRX

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell membrane, Cytoplasm, Membrane, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004348981 – 1349PeriaxinAdd BLAST1349

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei7PhosphoserineBy similarity1
Modified residuei133PhosphoserineBy similarity1
Modified residuei794PhosphoserineBy similarity1
Modified residuei974PhosphoserineBy similarity1
Modified residuei1236PhosphoserineBy similarity1
Modified residuei1240PhosphoserineBy similarity1
Modified residuei1242PhosphoserineBy similarity1
Modified residuei1289PhosphoserineBy similarity1
Modified residuei1295PhosphoserineBy similarity1
Modified residuei1327PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E1BM58

PRoteomics IDEntifications database

More...
PRIDEi
E1BM58

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in eye lens (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSBTAG00000017333, Expressed in lung and 11 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E1BM58, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (via PDZ domain) (By similarity).

Interacts with SCN10A.

Found in a complex with SCN10A (By similarity).

Interacts with DRP2.

Identified in a dystroglycan complex that contains at least PRX, DRP2, UTRN, DMD and DAG1 (By similarity). Detected in a complex composed of at least EZR, AHNAK, PPL and PRX (PubMed:14625392).

Identified in a complex with EZR, AHNAK, BFSP1, BFSP2, ANK2, PLEC, VIM and spectrin (By similarity).

By similarity

Protein-protein interaction databases

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
E1BM58

STRING: functional protein association networks

More...
STRINGi
9913.ENSBTAP00000010183

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E1BM58

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini16 – 99PDZPROSITE-ProRule annotationAdd BLAST84
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati402 – 4061Curated5
Repeati410 – 4142Curated5
Repeati418 – 4223Curated5
Repeati426 – 4304Curated5
Repeati431 – 4355Curated5
Repeati436 – 4406Curated5
Repeati444 – 4487Curated5
Repeati452 – 4568Curated5
Repeati457 – 4619Curated5
Repeati462 – 46610Curated5
Repeati467 – 47111Curated5
Repeati472 – 47612Curated5
Repeati477 – 48113Curated5
Repeati485 – 48914Curated5
Repeati493 – 49715Curated5
Repeati501 – 50516Curated5
Repeati506 – 51017Curated5
Repeati514 – 51818Curated5
Repeati519 – 52319Curated5
Repeati524 – 52820Curated5
Repeati532 – 53621Curated5
Repeati537 – 54922CuratedAdd BLAST13
Repeati553 – 55723Curated5
Repeati558 – 56224Curated5
Repeati563 – 56725Curated5
Repeati571 – 57526Curated5
Repeati576 – 58027Curated5
Repeati589 – 59328Curated5
Repeati594 – 59829Curated5
Repeati599 – 60330Curated5
Repeati612 – 61631Curated5
Repeati617 – 62132Curated5
Repeati622 – 62633Curated5
Repeati630 – 63434Curated5
Repeati635 – 63935Curated5
Repeati643 – 64736Curated5
Repeati648 – 65237Curated5
Repeati653 – 65738Curated5
Repeati661 – 66539Curated5
Repeati669 – 67340Curated5
Repeati674 – 67841Curated5

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni402 – 67841 X 5 AA approximate tandem repeats of [LVMGIE]-[PSM]-[EDKA]-[LIVMA]-[AQKHPRT]; that may have a tripeptide spacer of [ALKD]-[IPV]-[KPH]CuratedAdd BLAST277

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi70 – 84Nuclear export signalBy similarityAdd BLAST15

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi136 – 139Poly-LysSequence analysis4
Compositional biasi209 – 212Poly-AlaSequence analysis4
Compositional biasi769 – 772Poly-AlaSequence analysis4

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Has a remarkable domain of repetitive pentameric units sometimes followed by a tripeptide spacer, it may separate two functional basic and acidic domains.Curated
The Arg/Lys-rich basic domain functions as a tripartite nuclear localization signal.By similarity
The PDZ domain contains the signal for export from the nucleus (By similarity). The N-terminal region including the PDZ domain is required for the formation of Cajal bands on myelinated nerves (By similarity).By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the periaxin family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QS7Y, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160366

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_252008_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E1BM58

Database of Orthologous Groups

More...
OrthoDBi
71329at2759

TreeFam database of animal gene trees

More...
TreeFami
TF350595

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001478, PDZ
IPR036034, PDZ_sf

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156, SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106, PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E1BM58-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEARSRSAEE LRRAELVEII VETEAQTGVS GINVAGGGKE GIFVRDLRED
60 70 80 90 100
SPAARSLSLQ EGDQLLSARV FFENFKYEDA LRLLQCAEPY KVSFCLKRTV
110 120 130 140 150
PTGDLALRPG TVAGYEIKGP RAKVAKLNIQ SLSPVKKKKM VMPGALGAPA
160 170 180 190 200
DLAPVDVEFS FPKFSRLRRG LKAEAVEGPV PAAPTRRRLQ LPRLRVREVA
210 220 230 240 250
EEAQVARLAA AAPPPRKAKA EAEVAAGPRF TAPQVELVGP RLPGAEVGVP
260 270 280 290 300
QVPAPKREAA PAVEPAAVGI QVPQVELPSL PSLPALPTLP CLETREGAVA
310 320 330 340 350
VTVPTLDVAA PTVGVDLALP GAEVEPREEV PEVALKMPRL SFPRFGARAK
360 370 380 390 400
EAAEAKVKGP KLRMPTFGLS LLEPRPAVPE APESKLKLPT IKIPSFGIGV
410 420 430 440 450
SPPEVKVPKG PEVKPPKVPE VKLPKMPEPV LPEVRLPEVE LPKVSEMKLP
460 470 480 490 500
KVPEMAVPEV RLPEVQLPKV PEMKLPEVKL PKVPEMAVPE VHLPEVQLPK
510 520 530 540 550
VPEMKLPEVK LPKVPEMAVP EVRLPEVQLP KVPEMKLPKV PEMKCPEMKL
560 570 580 590 600
PKVPEMAVPE VRLPEVQLPK VPEVKLPEVK LPEVKLPKVP EMAVPEVHLP
610 620 630 640 650
EVQLPKVSEM KVPDVKLPEV KLPEIKLPKV PEMVVPDVHL PQVHLPKVSE
660 670 680 690 700
MRLPEVQAPK VPEVHLPKAP EVKLPKAPEA QLKAARVEEA EGMDFGFKMP
710 720 730 740 750
KMTLPKLGRA ESPSQGKPGE AGAEVSGKLV TLPCLQPEVG SEARVGVPRL
760 770 780 790 800
TLPSVELDLP GALGLEGQAA AAEVGKGEQA EAAGVGEVAF RLPSVEIVTP
810 820 830 840 850
QLPTLDEGQA EVTEAKVKLS SKFSLPKFGL SGPKVTKPEA EGAGRAAKLK
860 870 880 890 900
VSKFAISLPR ARVGTEVEAK GTEEAGLLPA LDLSIPQLSL DSHLPTGKAE
910 920 930 940 950
VAGADIKLKG PKFGLPKFGV RGRDTEAGEL VPGAAELEGK SRGWDGKVKM
960 970 980 990 1000
PKLKMPSFGL ARGKEADISG GQVSPGEKPE STAVQLKIPE VELVTLGAQE
1010 1020 1030 1040 1050
EGRVEEEAAG SRGRLAGLQV SPAKQVGTEA QDGGLRMPLG ISLPQVELTG
1060 1070 1080 1090 1100
FREATPGQQA ESSAPPAEGT AGYRVHVPQV TLALPGAQAV GGELLVGEGV
1110 1120 1130 1140 1150
FKMPSVTVPQ LELDVGLSRE VQDGEAATSE GGLKLKVPTL GARAGAGAEG
1160 1170 1180 1190 1200
PSDQSAGAER TFHLSLPDVE LSPPAVGTHA EYQVAEGEGD AGHKLKVRLP
1210 1220 1230 1240 1250
RFGLARAKEG AEEGEKAKSP KLKLPHVGFS QSEAVSGEGS PSPEEEDVEG
1260 1270 1280 1290 1300
GGEGASGRRG RVRVRLPRVG LAAPSKASRG QEGKAAPKSP SGEKSPKFRF
1310 1320 1330 1340
PRVSLSPKTR GGSGDQDEGG FRVRLPSVGF SETGPPGPTR MEGAQAAVI
Length:1,349
Mass (Da):142,695
Last modified:December 9, 2015 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE24F403249AA877
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DAAA02047080 Genomic DNA No translation available.
DV920320 mRNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_003587302.2, XM_003587254.4
XP_015322984.1, XM_015467498.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSBTAT00000010183; ENSBTAP00000010183; ENSBTAG00000017333

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
520296

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bta:520296

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02047080 Genomic DNA No translation available.
DV920320 mRNA No translation available.
RefSeqiXP_003587302.2, XM_003587254.4
XP_015322984.1, XM_015467498.1

3D structure databases

SMRiE1BM58
ModBaseiSearch...

Protein-protein interaction databases

CORUMiE1BM58
STRINGi9913.ENSBTAP00000010183

Proteomic databases

PaxDbiE1BM58
PRIDEiE1BM58

Genome annotation databases

EnsembliENSBTAT00000010183; ENSBTAP00000010183; ENSBTAG00000017333
GeneIDi520296
KEGGibta:520296

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57716
VGNCiVGNC:33430, PRX

Phylogenomic databases

eggNOGiENOG502QS7Y, Eukaryota
GeneTreeiENSGT00940000160366
HOGENOMiCLU_252008_0_0_1
InParanoidiE1BM58
OrthoDBi71329at2759
TreeFamiTF350595

Gene expression databases

BgeeiENSBTAG00000017333, Expressed in lung and 11 other tissues
ExpressionAtlasiE1BM58, baseline

Family and domain databases

Gene3Di2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR001478, PDZ
IPR036034, PDZ_sf
SMARTiView protein in SMART
SM00228, PDZ, 1 hit
SUPFAMiSSF50156, SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106, PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRAX_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1BM58
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 9, 2015
Last sequence update: December 9, 2015
Last modified: October 7, 2020
This is version 52 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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