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Entry version 73 (07 Oct 2020)
Sequence version 3 (10 Apr 2019)
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Protein
Submitted name:

AT-rich interaction domain 1B

Gene

ARID1B

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AT-rich interaction domain 1BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARID1BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:26124, ARID1B

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
E1BKQ8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSBTAG00000002728, Expressed in skeletal muscle tissue and 19 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E1BKQ8, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini648 – 739ARIDInterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 418DisorderedSequence analysisAdd BLAST418
Regioni476 – 637DisorderedSequence analysisAdd BLAST162
Regioni742 – 952DisorderedSequence analysisAdd BLAST211
Regioni987 – 1160DisorderedSequence analysisAdd BLAST174
Regioni1293 – 1361DisorderedSequence analysisAdd BLAST69
Regioni1416 – 1453DisorderedSequence analysisAdd BLAST38
Regioni1466 – 1485DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi26 – 40PolarSequence analysisAdd BLAST15
Compositional biasi59 – 73PolarSequence analysisAdd BLAST15
Compositional biasi104 – 131PolarSequence analysisAdd BLAST28
Compositional biasi144 – 173PolarSequence analysisAdd BLAST30
Compositional biasi180 – 198PolarSequence analysisAdd BLAST19
Compositional biasi217 – 254PolarSequence analysisAdd BLAST38
Compositional biasi269 – 287PolarSequence analysisAdd BLAST19
Compositional biasi297 – 313PolarSequence analysisAdd BLAST17
Compositional biasi323 – 346PolarSequence analysisAdd BLAST24
Compositional biasi354 – 416PolarSequence analysisAdd BLAST63
Compositional biasi481 – 544PolarSequence analysisAdd BLAST64
Compositional biasi556 – 570PolyampholyteSequence analysisAdd BLAST15
Compositional biasi571 – 586PolarSequence analysisAdd BLAST16
Compositional biasi596 – 637PolarSequence analysisAdd BLAST42
Compositional biasi754 – 786PolarSequence analysisAdd BLAST33
Compositional biasi802 – 846PolarSequence analysisAdd BLAST45
Compositional biasi875 – 904PolarSequence analysisAdd BLAST30
Compositional biasi930 – 951PolarSequence analysisAdd BLAST22
Compositional biasi1031 – 1065PolarSequence analysisAdd BLAST35
Compositional biasi1089 – 1118PolarSequence analysisAdd BLAST30
Compositional biasi1125 – 1157PolarSequence analysisAdd BLAST33
Compositional biasi1293 – 1307PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1308 – 1336AcidicSequence analysisAdd BLAST29
Compositional biasi1437 – 1453PolyampholyteSequence analysisAdd BLAST17

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155634

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038040, ARID1B
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR021906, BAF250/Osa
IPR033388, BAF250_C

The PANTHER Classification System

More...
PANTHERi
PTHR12656, PTHR12656, 1 hit
PTHR12656:SF11, PTHR12656:SF11, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388, ARID, 1 hit
PF12031, BAF250_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501, BRIGHT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774, SSF46774, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011, ARID, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E1BKQ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLGKDMGAQ YAAASPAWAA AQQRSHPAMS PGTPGPTMGR SQGSPMDPMV
60 70 80 90 100
MKRPQLYGMG SNPHSQPQQS SPYPGGSYGP PGPQRYPIGI QGRPPGAMGG
110 120 130 140 150
MQYPQQQMPA QYGQQGVSGY CQQGQQPYYN QQPQPPHLPP QAPYLPSQSQ
160 170 180 190 200
QRYQPQQDMS QEGYGTRSQP PLASGKPNHE DLNLIQQERP SSLPVEVLTS
210 220 230 240 250
EDTAFGLKDL SGSIDDLPTG TEATLSSAVS ASGSTSSQGD QSNPAQSPFS
260 270 280 290 300
PHASPHLSSI PGGPSPSPVG SPVGSNQSRS GPISPASIPG SQMPPQPPGN
310 320 330 340 350
QSESSSHPAL SQSPMPQERG FMAGTQRNPQ MSQYGPQQTG PSMSPHPSPG
360 370 380 390 400
GQMHPGISSF QQSNSSGTYG PQMSQYGPQG NYSRPPTYSG VPSASYSGPG
410 420 430 440 450
PSMGVNANSQ MHGQGPSQPC GAMPLGRVPS AGMQNRPFPG NMSSMTPSSP
460 470 480 490 500
GMSQQGGPGM GPPMPTVNRK AQEAAAAVMQ AAANSAQSRQ GGFPGMNQSG
510 520 530 540 550
LMASSSPYSQ PMNNSSGLMN TQAPPYSMTP NMVNSSTASM GLADMMSPSE
560 570 580 590 600
SKLPLPLKAD GKEEGSTQPE GKSKDSYSSQ GISQPPTPGN LPVPSPMSPS
610 620 630 640 650
SASISSFHGD ESDSISSPGW PKTPSSPKSS SSTTTGEKIT KVYELGNEPE
660 670 680 690 700
RKLWVDRYLT FMEERGSPVS SLPAVGKKPL DLFRLYVCVK EIGGLAQVNK
710 720 730 740 750
NKKWRELATN LNVGTSSSAA SSLKKQYIQY LFAFECKIER GEEPPPEVFS
760 770 780 790 800
TGDTKKQPKL QPPSPANSGS LQGPQTPQST GSNSMAEVPG DLKPPTPAST
810 820 830 840 850
PHGQMTPMQG GRSSTVSVHD PFSDASESSF PKRNSMTPST PYQQGMSMPD
860 870 880 890 900
VMGRMPYEPN KDPFGGMRKV PGSSEPFMTQ GQMPTSSMQD MYNQSPSGAM
910 920 930 940 950
SSLGMGPRQQ FPYGTSYDRR HEPYGQQYPG QGPPSGQPSY GGHQPGLYPQ
960 970 980 990 1000
QTNYKRHMDG MYGPPAKRHE GDMYNMQYGS QQQEMYNQYG SSYSGPDRRP
1010 1020 1030 1040 1050
LQGQYPYPYN RERMQGPGQI QPHAIPPQMM GGPMQSSSNE GPQQSMWATR
1060 1070 1080 1090 1100
NDMPYPYQNR QGPGGPTQAP PYPGINRTDD MMVPDQRINH ESQWPSHVSQ
1110 1120 1130 1140 1150
RQPYMSSSAS MQPITRPPQS SYQTPPSLPN HISRAPSPAS FQRSLESRMS
1160 1170 1180 1190 1200
PSKSPFLPSM KMQKVMPTVP TSQVTGPPPQ PPPIRREITF PPGSVEASQP
1210 1220 1230 1240 1250
VLKQRRKITS KDIVTPEAWR VMMSLKSGLL AESTWALDTI NILLYDDSTV
1260 1270 1280 1290 1300
ATFNLSQLSG FLELLVEYFR KCLIDIFGIL TEYEVGDPSQ KALDHNAAKR
1310 1320 1330 1340 1350
DDSQSLADDS GREEEDAECI EEEEDEEDEE EEDSGRAETE DRSSAAVASP
1360 1370 1380 1390 1400
DATTDLKEKP RQASKFDKLP IKIVKKNNLF VVDRSDKLGR VQEFSSGLLH
1410 1420 1430 1440 1450
WQLGGGDTTE HIQTHFESKM EIPPRRRPPP TLSSTGRKKD QEGKGDSDEH
1460 1470 1480 1490 1500
QEKSIIATID DVLSARPGAL PEDANPGTQT ESSKFPFGIH QARSHRNIKL
1510 1520 1530 1540 1550
LEDEPRSRDE APLCTIAHWQ DSLAKRCICV SNIVRSLSFV PGNDAEMSKH
1560 1570 1580 1590 1600
PGLVLILGKL ILLHHEHPER KRAPQTYEKE EDEDKGVACS KDEWWWDCLE
1610 1620 1630 1640 1650
VLRDNTLVTL ANISGQLDLS AYTESICLPI LDGLLHWMVC PSAEAQDPFP
1660 1670 1680 1690 1700
TVGPNSVLSP QRLVLETLCK LSIQDNNVDL ILATPPFSRQ EKFYATLVRY
1710 1720 1730 1740 1750
VGDRKNPVCR EMSMALLSNL AQGDALAARA IAVQKGSIGN LISFLEDGVT
1760 1770 1780 1790 1800
MAQYQQSQHN LMHMQPPPLE PPSVDMMCRA AKALLAMARV DENRSEFLLH
1810 1820 1830
EGRLLDISIS AVLNSLVASV ICDVLFQIGQ L
Length:1,831
Mass (Da):198,394
Last modified:April 10, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA75210FB27498037
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q1MXM3A0A3Q1MXM3_BOVIN
AT-rich interaction domain 1B
ARID1B
1,874Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F1MKU0F1MKU0_BOVIN
AT-rich interaction domain 1B
ARID1B
1,801Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q1LY23A0A3Q1LY23_BOVIN
AT-rich interaction domain 1B
ARID1B
1,860Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q1M0A5A0A3Q1M0A5_BOVIN
AT-rich interaction domain 1B
ARID1B
1,821Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSBTAT00000003537; ENSBTAP00000003537; ENSBTAG00000002728

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiE1BKQ8

Genome annotation databases

EnsembliENSBTAT00000003537; ENSBTAP00000003537; ENSBTAG00000002728

Organism-specific databases

VGNCiVGNC:26124, ARID1B

Phylogenomic databases

GeneTreeiENSGT00940000155634

Gene expression databases

BgeeiENSBTAG00000002728, Expressed in skeletal muscle tissue and 19 other tissues
ExpressionAtlasiE1BKQ8, baseline and differential

Family and domain databases

Gene3Di1.10.150.60, 1 hit
InterProiView protein in InterPro
IPR038040, ARID1B
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR021906, BAF250/Osa
IPR033388, BAF250_C
PANTHERiPTHR12656, PTHR12656, 1 hit
PTHR12656:SF11, PTHR12656:SF11, 1 hit
PfamiView protein in Pfam
PF01388, ARID, 1 hit
PF12031, BAF250_C, 1 hit
SMARTiView protein in SMART
SM00501, BRIGHT, 1 hit
SUPFAMiSSF46774, SSF46774, 1 hit
PROSITEiView protein in PROSITE
PS51011, ARID, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE1BKQ8_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1BKQ8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: April 10, 2019
Last modified: October 7, 2020
This is version 73 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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