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Protein
Submitted name:

TNF receptor superfamily member 25

Gene

TNFRSF25

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-5669034 TNFs bind their physiological receptors

Names & Taxonomyi

Protein namesi
Submitted name:
TNF receptor superfamily member 25Imported
Gene namesi
Name:TNFRSF25Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 16

Organism-specific databases

VGNCiVGNC:36167 TNFRSF25

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei204 – 227HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_500314405730 – 418Sequence analysisAdd BLAST389

Proteomic databases

PaxDbiE1BHL8

Expressioni

Gene expression databases

BgeeiENSBTAG00000006519

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000008557

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 118TNFR-CysInterPro annotationAdd BLAST44
Repeati75 – 118TNFR-CysPROSITE-ProRule annotationAdd BLAST44
Domaini333 – 414DeathInterPro annotationAdd BLAST82

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IKG3 Eukaryota
ENOG410YHT0 LUCA
GeneTreeiENSGT00530000064001
InParanoidiE1BHL8
KOiK05160
OMAiGWRQMFW
OrthoDBiEOG091G07LE
TreeFamiTF333916

Family and domain databases

CDDicd13420 TNFRSF25, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022329 TNFR_25
IPR034050 TNFRSF25_N
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF00020 TNFR_c6, 1 hit
PRINTSiPR01972 TNFACTORR25
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SM00208 TNFR, 2 hits
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS00652 TNFR_NGFR_1, 1 hit
PS50050 TNFR_NGFR_2, 1 hit

Sequencei

Sequence statusi: Complete.

E1BHL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPRPRPGTS AAAAAAVALL FLLLLGARAS TPSPRCDCGH SFPKRSGLGC
60 70 80 90 100
CKGCPAGHYL KAPCTKPCGA ATCLPCPQGT FLARENHYET RCARCQACDE
110 120 130 140 150
LAPQMALRNC SAVADTHCGC RPGWFMDCMV SQCRHGSPFR CRPCTDCGAL
160 170 180 190 200
HRHTQTPCSS RDTHCGTCLP GFYEYDKSCV SCPTSTLGSC PEPCVAVCGW
210 220 230 240 250
RQMFWVQMLV AGLVVPLLLG ATLTYTYHRC HPCKAIGPAD DTGVEVWTPL
260 270 280 290 300
QTTHLSPPDS GPALLVTPSS SEKVCPVHLV GHSCTSGSPQ TQEAPCLEAT
310 320 330 340 350
WSWDQLPSRA PGLPPPPSPA PPAGSAAATL QPGPQLYDVM DAVPARRWKE
360 370 380 390 400
FMRTLGLREA EIEAVEVEVG RFRDQQYEML KRWRQQQHAG LGAVYAALER
410
MGLDGCAEDL RSRLQRGP
Length:418
Mass (Da):45,078
Last modified:November 2, 2010 - v1
Checksum:iF3AEB764CAB964C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02043084 Genomic DNA No translation available.
RefSeqiNP_001137549.1, NM_001144077.1
UniGeneiBt.30010

Genome annotation databases

EnsembliENSBTAT00000008557; ENSBTAP00000008557; ENSBTAG00000006519
GeneIDi783432
KEGGibta:783432

Similar proteinsi

Entry informationi

Entry nameiE1BHL8_BOVIN
AccessioniPrimary (citable) accession number: E1BHL8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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