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Entry version 59 (17 Jun 2020)
Sequence version 2 (16 Nov 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene

BBS9

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-BTA-5620922 BBSome-mediated cargo-targeting to cilium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BBS9Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E1BHJ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSBTAG00000006528 Expressed in testis and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
E1BHJ5, 2 interactors

STRING: functional protein association networks

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STRINGi
9913.ENSBTAP00000008587

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
E1BHJ5

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

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PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 417PHTB1_NInterPro annotationAdd BLAST417
Domaini441 – 819PHTB1_CInterPro annotationAdd BLAST379

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili371 – 398Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3679 Eukaryota
ENOG410XR64 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000803

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015674_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E1BHJ5

KEGG Orthology (KO)

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KOi
K19398

Identification of Orthologs from Complete Genome Data

More...
OMAi
DTHWAIR

Database of Orthologous Groups

More...
OrthoDBi
332152at2759

TreeFam database of animal gene trees

More...
TreeFami
TF314513

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028074 PHTB1_C_dom
IPR028073 PHTB1_N_dom
IPR026511 PTHB1

The PANTHER Classification System

More...
PANTHERi
PTHR20991 PTHR20991, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14728 PHTB1_C, 1 hit
PF14727 PHTB1_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E1BHJ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLFKARDWW STVLGDKEEF DQGCLCLADV DNTGNGQDKI IVGSFMGYLR
60 70 80 90 100
IFNPHPVKTG DGAQAEDLLL EVHLRDPILQ VEVGKFVSGT EMLHLAVLHS
110 120 130 140 150
RKLCVYSVSG TLGNVEHGNQ YQIKLMYEHN LQRTACNMTY GSFGGVKGRD
160 170 180 190 200
LICIQSVDGM LMVFEQESYA FGRFLPGSLL PGPLAYSSRT DSFITVSSCH
210 220 230 240 250
QVESYKYQVL AFATDADKRQ ETEQQKHGSG KRLVVDWTLN IGEQAIDICI
260 270 280 290 300
VSFIQSASSV FVLGERNFFC LKDNGQIQFM KKLDYSPSCF LPYCSVSEGT
310 320 330 340 350
INTLIGNHNN MLHIYQDVTL KWATQLPHVP VAVRVGCLHD LKGVIVTLSD
360 370 380 390 400
DGHLQCSYLG TDPSLFQAPK VESRELNYDE LDMELKELQK VIKNVNKSQD
410 420 430 440 450
VWPLTEREDD LKVSAMVSPN FDSVSQATDV EVGADLVPSV TVKVTLKNRV
460 470 480 490 500
ALQKIKLSIY VQPPLVLTGD QFTFEFMAPE MTRTVGFSVY LKGSYSPPEL
510 520 530 540 550
EGNAVVSYSR PTERNPDGIP RVSQCKFRLP LKLVCLPGQP SKTASHKLTI
560 570 580 590 600
DTNKSPVSLL SLFPGFAKQS EDDQVNVMGF RFLGGSQVTL LASKTSQRYR
610 620 630 640 650
IQSEQFEDLW LITNELIIRL QEYFEKQGIK DFTCSFSGSV PLEEYFELID
660 670 680 690 700
HHFELRINGE KLEELLSERA VQFRAIQRRL LTRFKDKTPA PLQHLDTLLD
710 720 730 740 750
GTYKQVIALA DAVEENQDNL FQSFTRLKSA THLVILLIGL WQKLSADQIA
760 770 780 790 800
ILEAAFLPLQ QDTQELGWEE TVDAALSHLL KTCLSKSSKE QALNLNSQLG
810 820 830 840 850
IPKDTSQLKK HITLFCDRLA KGGRLCLSTD AAAPQTMVMP GGCATIPESD
860 870 880
LEGRSIDQDS SELFTNHKHL MVETPVPEVS PLQGVTE
Length:887
Mass (Da):99,124
Last modified:November 16, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA66B895A9F9FECD
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
NP_001179782.1, NM_001192853.1
XP_005205535.1, XM_005205478.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSBTAT00000008587; ENSBTAP00000008587; ENSBTAG00000006528

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
535387

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bta:535387

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiNP_001179782.1, NM_001192853.1
XP_005205535.1, XM_005205478.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6VBUelectron microscopy3.1091-887[»]
6VBVelectron microscopy3.5091-887[»]
SMRiE1BHJ5
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiE1BHJ5, 2 interactors
STRINGi9913.ENSBTAP00000008587

Proteomic databases

PaxDbiE1BHJ5

Genome annotation databases

EnsembliENSBTAT00000008587; ENSBTAP00000008587; ENSBTAG00000006528
GeneIDi535387
KEGGibta:535387

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27241

Phylogenomic databases

eggNOGiKOG3679 Eukaryota
ENOG410XR64 LUCA
GeneTreeiENSGT00390000000803
HOGENOMiCLU_015674_1_0_1
InParanoidiE1BHJ5
KOiK19398
OMAiDTHWAIR
OrthoDBi332152at2759
TreeFamiTF314513

Enzyme and pathway databases

ReactomeiR-BTA-5620922 BBSome-mediated cargo-targeting to cilium

Gene expression databases

BgeeiENSBTAG00000006528 Expressed in testis and 9 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR028074 PHTB1_C_dom
IPR028073 PHTB1_N_dom
IPR026511 PTHB1
PANTHERiPTHR20991 PTHR20991, 1 hit
PfamiView protein in Pfam
PF14728 PHTB1_C, 1 hit
PF14727 PHTB1_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE1BHJ5_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1BHJ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 16, 2011
Last modified: June 17, 2020
This is version 59 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Reference proteomeImported
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