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Protein
Submitted name:

Myotubularin related protein 1

Gene

MTMR1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-1660499 Synthesis of PIPs at the plasma membrane

Names & Taxonomyi

Protein namesi
Submitted name:
Myotubularin related protein 1Imported
Gene namesi
Name:MTMR1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome X

Organism-specific databases

VGNCiVGNC:31736 MTMR1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE1BFE6

Expressioni

Gene expression databases

BgeeiENSBTAG00000009657

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000012726

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini246 – 621Myotubularin phosphataseInterPro annotationAdd BLAST376
Domaini427 – 489TYR_PHOSPHATASE_2InterPro annotationAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili638 – 665Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1089 Eukaryota
ENOG410XPTU LUCA
GeneTreeiENSGT00760000118832
InParanoidiE1BFE6
OMAiIAKDVMY
OrthoDBiEOG091G04DS
TreeFamiTF315197

Family and domain databases

CDDicd13358 PH-GRAM_MTMR1, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR004182 GRAM
IPR030587 MTMR1
IPR037857 MTMR1_PH-GRAM
IPR010569 Myotubularin-like_Pase_dom
IPR030564 Myotubularin_fam
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
PANTHERiPTHR10807 PTHR10807, 1 hit
PTHR10807:SF40 PTHR10807:SF40, 1 hit
PfamiView protein in Pfam
PF02893 GRAM, 1 hit
PF06602 Myotub-related, 1 hit
SMARTiView protein in SMART
SM00568 GRAM, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS51339 PPASE_MYOTUBULARIN, 1 hit
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

E1BFE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRPAAAAAA AAAGCDSGGG LGPGPAGGRR PPRVAGGPAV GSRQPSVETL
60 70 80 90 100
DSPTGSHVEW CKQLIAATIS SQISGSVTSE NVSRDYKEIQ EEHNGYPSEA
110 120 130 140 150
EADQALRDGN KLAQMEEAPL LPGESIKAIV KDVMYICPFV GAVTGTLTVT
160 170 180 190 200
DFKMYFKNVE RDPHFVLEVP LGVISRVEKI GAQSHGDNSC GIEIVCKDMR
210 220 230 240 250
NLRLAYKQEE QSKLGIFENL NKHAFPLSNG QTLFAFNYKE KFPVNGWKVY
260 270 280 290 300
DPVSEYKRQG LPNESWKISK VNSNYELCDT YPAIIVVPTS VKDDDLSKVA
310 320 330 340 350
AFRAKGRIPV LSWIHPESQA TITRCSQPLV GPNDKRCKED EKYLQTIMDA
360 370 380 390 400
NAQAHKLIIF DARQNSVADT NKAKGGGYES ESAYPNAELM FLEIHNIHVM
410 420 430 440 450
RESLRKLKEI AYPAIDEARW LSNVDGTHWL EYIRMLLAGA VRIADKVESG
460 470 480 490 500
KTSVVVHCSD GWDRTAQLTS LAMLMLDSYY RTIKGFEALI EKEWISFGHR
510 520 530 540 550
FALRVGHGND NHADADRSPI FLQFIDCVWQ MTRQFPSAFE FNEFFLITIL
560 570 580 590 600
DHLYSCLFGT FLCNCEQQRL KEDVSTKTVS LWSYINSQLD EFSNPFFVNY
610 620 630 640 650
ENHVLYPVAS LSHLELWVNY YVRWNPRMRP QTPTHQNLKE LLAVRAELQK
660 670 680
RVEDLQREVA ARASASSERG SSPSHSVTPV HTSV
Length:684
Mass (Da):76,566
Last modified:November 2, 2010 - v1
Checksum:i474F3E7E71280A72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02068143 Genomic DNA No translation available.
DAAA02068144 Genomic DNA No translation available.
DAAA02068145 Genomic DNA No translation available.
DAAA02068146 Genomic DNA No translation available.
DAAA02068147 Genomic DNA No translation available.
RefSeqiXP_010819804.1, XM_010821502.2
UniGeneiBt.54113

Genome annotation databases

EnsembliENSBTAT00000012726; ENSBTAP00000012726; ENSBTAG00000009657

Similar proteinsi

Entry informationi

Entry nameiE1BFE6_BOVIN
AccessioniPrimary (citable) accession number: E1BFE6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: July 18, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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