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Protein
Submitted name:

ATP binding cassette subfamily G member 1

Gene

ABCG1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi117 – 124ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-BTA-1369062 ABC transporters in lipid homeostasis
R-BTA-8964058 HDL remodeling

Names & Taxonomyi

Protein namesi
Submitted name:
ATP binding cassette subfamily G member 1Imported
Gene namesi
Name:ABCG1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 1

Organism-specific databases

VGNCiVGNC:25483 ABCG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei414 – 431HelicalSequence analysisAdd BLAST18
Transmembranei443 – 464HelicalSequence analysisAdd BLAST22
Transmembranei484 – 509HelicalSequence analysisAdd BLAST26
Transmembranei521 – 545HelicalSequence analysisAdd BLAST25
Transmembranei551 – 573HelicalSequence analysisAdd BLAST23
Transmembranei585 – 603HelicalSequence analysisAdd BLAST19
Transmembranei635 – 657HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE1BDU6

Expressioni

Gene expression databases

BgeeiENSBTAG00000021272 Expressed in 8 organ(s), highest expression level in prefrontal cortex

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028342

Structurei

3D structure databases

ProteinModelPortaliE1BDU6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 316ABC transporterInterPro annotationAdd BLAST241

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0061 Eukaryota
COG1131 LUCA
GeneTreeiENSGT00740000114855
InParanoidiE1BDU6
OMAiQGQCIYR
OrthoDBiEOG091G050S
TreeFamiTF105210

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013525 ABC_2_trans
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR020064 ABCG1
IPR027417 P-loop_NTPase
IPR005284 Pigment_permease/Abcg
PANTHERiPTHR19241:SF177 PTHR19241:SF177, 1 hit
PfamiView protein in Pfam
PF01061 ABC2_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00955 3a01204, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

E1BDU6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MACLMATFSV GTAMNGSSGM TEPKSVCVSV DEVVFSNRDR DTVEKELLNG
60 70 80 90 100
HLKKEDNNLT EAQRLSSLPR RAAVNIEFKD LSYSVSEGPW WRKKGYKTLL
110 120 130 140 150
KGISGKFNSG ELVAIMGPSG AGKSTLMNIL AGYRETGMKG EVLINGLPRD
160 170 180 190 200
LRCFRKVSCY IMQDDLLLPH LTVQEAMMVS AHLKLQEKDE GRREMVKEIL
210 220 230 240 250
TALGLLSCAN TRTGSLSGGQ RKRLAIALEL VNNPPVMFFD EPTSGLDSAS
260 270 280 290 300
CFQVVSLMKG LAQGGRSIIC TIHQPSAKLF ELFDQLYVLS QGQCVYRGKV
310 320 330 340 350
SNLVPYLRDL GLNCPTYHNP ADFVMEVASG EYGDQNGRLV RAVWEGKCDS
360 370 380 390 400
DCRREPGGDA EVNPFIWHRP SEEDSTSMEG CHSFSASCLT QFCILFKRTF
410 420 430 440 450
LSIMRDSVLT HLRITSHIGI GLLIGLLYLG IGNEAKKVLS NSGFLFFSML
460 470 480 490 500
FLMFAALMPT VLTFPLEMSV FLREHLNYWY SLKAYYLAKT MADVPFQIMF
510 520 530 540 550
PVAYCSIVYW MTSQPSDAVR FVLFAALGTM TSLVAQSLGL LIGAASTSLQ
560 570 580 590 600
VATFVGPVTA IPVLLFSGFF VSFDTIPTYL QWMSYVSYVR YGFEGVILSI
610 620 630 640 650
YGLDREDLHC NTNETCHFQK SEAILRELDV ENAKLYLDFI VLGIFFISLR
660
LIAYLVLRYK IRAER
Length:665
Mass (Da):74,142
Last modified:November 2, 2010 - v1
Checksum:i710F7956734775FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02003260 Genomic DNA No translation available.
RefSeqiXP_005202056.1, XM_005201999.3

Genome annotation databases

EnsembliENSBTAT00000028342; ENSBTAP00000028342; ENSBTAG00000021272
GeneIDi510745

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02003260 Genomic DNA No translation available.
RefSeqiXP_005202056.1, XM_005201999.3

3D structure databases

ProteinModelPortaliE1BDU6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028342

Proteomic databases

PaxDbiE1BDU6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000028342; ENSBTAP00000028342; ENSBTAG00000021272
GeneIDi510745

Organism-specific databases

CTDi9619
VGNCiVGNC:25483 ABCG1

Phylogenomic databases

eggNOGiKOG0061 Eukaryota
COG1131 LUCA
GeneTreeiENSGT00740000114855
InParanoidiE1BDU6
OMAiQGQCIYR
OrthoDBiEOG091G050S
TreeFamiTF105210

Enzyme and pathway databases

ReactomeiR-BTA-1369062 ABC transporters in lipid homeostasis
R-BTA-8964058 HDL remodeling

Gene expression databases

BgeeiENSBTAG00000021272 Expressed in 8 organ(s), highest expression level in prefrontal cortex

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013525 ABC_2_trans
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR020064 ABCG1
IPR027417 P-loop_NTPase
IPR005284 Pigment_permease/Abcg
PANTHERiPTHR19241:SF177 PTHR19241:SF177, 1 hit
PfamiView protein in Pfam
PF01061 ABC2_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00955 3a01204, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE1BDU6_BOVIN
AccessioniPrimary (citable) accession number: E1BDU6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: September 12, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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