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Entry version 80 (02 Jun 2021)
Sequence version 3 (10 Apr 2019)
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Protein

Sodium channel protein

Gene

SCN3A

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.

UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Sodium channelUniRule annotationARBA annotation, Voltage-gated channelUniRule annotation
Biological processIon transport, Sodium transport, Transport
LigandSodium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium channel proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCN3AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:55078, SCN3A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei61 – 80HelicalUniRule annotationAdd BLAST20
Transmembranei92 – 113HelicalUniRule annotationAdd BLAST22
Transmembranei119 – 139HelicalUniRule annotationAdd BLAST21
Transmembranei269 – 296HelicalUniRule annotationAdd BLAST28
Transmembranei613 – 631HelicalUniRule annotationAdd BLAST19
Transmembranei643 – 666HelicalUniRule annotationAdd BLAST24
Transmembranei723 – 751HelicalUniRule annotationAdd BLAST29
Transmembranei813 – 836HelicalUniRule annotationAdd BLAST24
Transmembranei1059 – 1077HelicalUniRule annotationAdd BLAST19
Transmembranei1098 – 1120HelicalUniRule annotationAdd BLAST23
Transmembranei1126 – 1146HelicalUniRule annotationAdd BLAST21
Transmembranei1175 – 1201HelicalUniRule annotationAdd BLAST27
Transmembranei1296 – 1320HelicalUniRule annotationAdd BLAST25
Transmembranei1379 – 1397HelicalUniRule annotationAdd BLAST19
Transmembranei1409 – 1427HelicalUniRule annotationAdd BLAST19
Transmembranei1434 – 1459HelicalUniRule annotationAdd BLAST26
Transmembranei1496 – 1524HelicalUniRule annotationAdd BLAST29
Transmembranei1600 – 1623HelicalUniRule annotationAdd BLAST24

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501876831518 – 1852Sodium channel proteinSequence analysisAdd BLAST1835

Keywords - PTMi

Disulfide bondARBA annotation, PhosphoproteinARBA annotation, Ubl conjugationARBA annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E1B9G2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSBTAG00000019385, Expressed in occipital lobe and 51 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9913.ENSBTAP00000025829

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 303Ion_transInterPro annotationAdd BLAST303
Domaini376 – 562Na_trans_cytoplInterPro annotationAdd BLAST187
Domaini613 – 841Ion_transInterPro annotationAdd BLAST229
Domaini850 – 1052Na_trans_assocInterPro annotationAdd BLAST203
Domaini1057 – 1328Ion_transInterPro annotationAdd BLAST272
Domaini1378 – 1633Ion_transInterPro annotationAdd BLAST256

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni362 – 398DisorderedSequence analysisAdd BLAST37
Regioni458 – 500DisorderedSequence analysisAdd BLAST43
Regioni969 – 1013DisorderedSequence analysisAdd BLAST45
Regioni1801 – 1852DisorderedSequence analysisAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili293 – 334Sequence analysisAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi377 – 398Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi458 – 491Basic and acidic residuesSequence analysisAdd BLAST34
Compositional biasi1803 – 1824Polar residuesSequence analysisAdd BLAST22
Compositional biasi1825 – 1852Basic and acidic residuesSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sodium channel (TC 1.A.1.10) family. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixUniRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2301, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157130

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000540_5_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E1B9G2

Identification of Orthologs from Complete Genome Data

More...
OMAi
AFETNIT

TreeFam database of animal gene trees

More...
TreeFami
TF323985

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13433, Na_channel_gate, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005821, Ion_trans_dom
IPR000048, IQ_motif_EF-hand-BS
IPR001696, Na_channel_asu
IPR044564, Na_chnl_inactivation_gate
IPR010526, Na_trans_assoc
IPR024583, Na_trans_cytopl
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10037, PTHR10037, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520, Ion_trans, 4 hits
PF06512, Na_trans_assoc, 1 hit
PF11933, Na_trans_cytopl, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00170, NACHANNEL

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096, IQ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E1B9G2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLIMCTILTN CVFMTLSNPP DWTKNVEYTF TGIYTFESLI KILARGFCLE
60 70 80 90 100
DFTFLRDPWN WLDFSVIVMA YVTEFVNLGN VSALRTFRVL RALKTISVIP
110 120 130 140 150
GLKTIVGALI QSVKKLSDVM ILTVFCLSVF ALIGLQLFMG NLRNKCLQWP
160 170 180 190 200
PSDSAFETNT TSLFNGTMNS NGTFVNVTMS TFNWKDYIED DSHFYVLDGQ
210 220 230 240 250
NDPLLCGNGS DAGQCPEGYI CVKAGRNPNY GYTSFDTFSW AFLSLFRLMT
260 270 280 290 300
QDYWENLYQL TLRAAGKTYM IFFVLVIFLG SFYLVNLILA VVAMAYEEQN
310 320 330 340 350
QATLEEAEQK EAEFQQMLEQ IKKQQEEAQA VAAASAASRD FSGIGGLGEL
360 370 380 390 400
LESSSEASKL SSKSAKEWRN RRKKRRQREN LEGNNKGEGN RFPKSESEDS
410 420 430 440 450
VKRRSFLFSM DGNRLTSDKK FYSPHQSLLS IRGSLFSPRR NSKTSIFSFR
460 470 480 490 500
GRAKDIGSEN DFADDEHSTF EDSESRRDSL FVPHRHGERR NSNVSQASMS
510 520 530 540 550
SRMVPGLPAN GKMHSTVDCN GVVSLGTTTE TEVRKRRLSS YQISMEMLED
560 570 580 590 600
SSGRQRAMSI ASILTNTMEE LEESRQKCPP CWYRFANMFL IWDCCDAWLK
610 620 630 640 650
VKHLVNLIVM DPFVDLAITI CIVLNTLFMA MEHYPMTGQF SSVLTVGNLV
660 670 680 690 700
FTGIFTAEMV LKIIAMDPYY YFQEGWNIFD GIIVSLSLME LGLANVEGLS
710 720 730 740 750
VLRSFRLLRV FKLAKSWPTL NMLIKIIGNS VGALGNLTLV LAIIVFIFAV
760 770 780 790 800
VGMQLFGKSY KECVCKISSD CELPRWHMND FFHSFLIVFR VLCGEWIETM
810 820 830 840 850
WDCMEVAGQT MCLIVFMLVM VIGNLVVLNL FLALLLSSFS SDNLAATDDD
860 870 880 890 900
NEMNNLQIAV GRMQKGIDYV KNKIRECFQK TFFRKPKVIE IHEGNKIDSC
910 920 930 940 950
VSNNTGIEIS KELNYLKDGN GTTSGVGTGS SAEKYVIDEN DYMSFINNPS
960 970 980 990 1000
LTVTVPIAVG ESDFENLNTE EFSSESELEE SKEKLNATSS SEGSTVDVAP
1010 1020 1030 1040 1050
PREGEQAEIE PEEDLKPEAC FTEGCIKKFP FCQVSIEEGK GKIWWNLRKT
1060 1070 1080 1090 1100
CYSIVEHNWF ETFIVFMILL SSGALAFEDI YIEQRKTIKT MLEYADKVFT
1110 1120 1130 1140 1150
YIFILEMLLK WVAYGFQTYF TNAWCWLDFL IVDVSLVSLV ANALGYSELG
1160 1170 1180 1190 1200
AIKSLRTLRA LRPLRALSRF EGMRVVVNAL VGAIPSIMNV LLVCLIFWLI
1210 1220 1230 1240 1250
FSIMGVNLFA GKFYHCVNTT TGNMFDVSEV NNLSDCQALG KKARWKNVKV
1260 1270 1280 1290 1300
NFDNVGAGYL ALLQVATFKG WMDIMYAAVD SRDVKLQPVY EENLYMYLYF
1310 1320 1330 1340 1350
VIFIIFGSFF TLNLFIGVII DNFNQQKKKF GGQDIFMTEE QKKYYNAMKK
1360 1370 1380 1390 1400
LGSKKPQKPI PRPANKFQGM VFDFVTRQVF DISIMILICL NMVTMMVETD
1410 1420 1430 1440 1450
DQSKYMTLVL SRINLVFIIL FTGEFVLKLI SLRYYYFTIG WNIFDFVVVI
1460 1470 1480 1490 1500
LSIVGMFLAE LIEKYFVSPT LFRVIRLARI GRILRLIKGA KGIRTLLFAL
1510 1520 1530 1540 1550
MMSLPALFNI GLLLFLVMFI YAIFGMSNFA YVKKEAGIDD MFNFETFGNS
1560 1570 1580 1590 1600
MICLFQITTS AGWDGLLAPI LNSAPPDCDP DTIHPGSSVK GDCGNPSVGI
1610 1620 1630 1640 1650
FFFVSYIIIS FLVVVNMYIA VILENFSVAT EESAEPLSED DFEMFYEVWE
1660 1670 1680 1690 1700
KFDPDATQFI EFSKLSDFAA ALDPPLLIAK PNKVQLIAMD LPMVSGDRIH
1710 1720 1730 1740 1750
CLDILFAFTK RVLGESGEMD ALRIQMEDRF MASNPSKVSY EPITTTLKRK
1760 1770 1780 1790 1800
QEEVSAAIIQ RNFRCYLLKQ RLKKVVNEYN KEAIKGRIDL PIKDDMIIDK
1810 1820 1830 1840 1850
LNGNSTPEKT DGSSSTTSPP SYDSVTKPDK EKFEKDKPEK ESKGKEVREN

QK
Length:1,852
Mass (Da):210,016
Last modified:April 10, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1B6752632130C754
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSBTAT00000025829; ENSBTAP00000025829; ENSBTAG00000019385

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000025829

Proteomic databases

PaxDbiE1B9G2

Genome annotation databases

EnsembliENSBTAT00000025829; ENSBTAP00000025829; ENSBTAG00000019385

Organism-specific databases

VGNCiVGNC:55078, SCN3A

Phylogenomic databases

eggNOGiKOG2301, Eukaryota
GeneTreeiENSGT00940000157130
HOGENOMiCLU_000540_5_0_1
InParanoidiE1B9G2
OMAiAFETNIT
TreeFamiTF323985

Gene expression databases

BgeeiENSBTAG00000019385, Expressed in occipital lobe and 51 other tissues

Family and domain databases

CDDicd13433, Na_channel_gate, 1 hit
Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR005821, Ion_trans_dom
IPR000048, IQ_motif_EF-hand-BS
IPR001696, Na_channel_asu
IPR044564, Na_chnl_inactivation_gate
IPR010526, Na_trans_assoc
IPR024583, Na_trans_cytopl
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf
PANTHERiPTHR10037, PTHR10037, 1 hit
PfamiView protein in Pfam
PF00520, Ion_trans, 4 hits
PF06512, Na_trans_assoc, 1 hit
PF11933, Na_trans_cytopl, 1 hit
PRINTSiPR00170, NACHANNEL
PROSITEiView protein in PROSITE
PS50096, IQ, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE1B9G2_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1B9G2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: April 10, 2019
Last modified: June 2, 2021
This is version 80 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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