Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 63 (02 Jun 2021)
Sequence version 3 (10 Apr 2019)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Repetin

Gene

RPTN

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RepetinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPTNImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:55674, RPTN

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E1B971

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSBTAG00000039260, Expressed in surface of tongue and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9913.ENSBTAP00000052019

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini49 – 84EF-handInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni93 – 209DisorderedSequence analysisAdd BLAST117
Regioni224 – 1036DisorderedSequence analysisAdd BLAST813

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi119 – 185Basic and acidic residuesSequence analysisAdd BLAST67
Compositional biasi186 – 207Polar residuesSequence analysisAdd BLAST22
Compositional biasi224 – 427Polar residuesSequence analysisAdd BLAST204
Compositional biasi435 – 454Polar residuesSequence analysisAdd BLAST20
Compositional biasi465 – 490Polar residuesSequence analysisAdd BLAST26
Compositional biasi491 – 505Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi506 – 526Polar residuesSequence analysisAdd BLAST21
Compositional biasi537 – 562Polar residuesSequence analysisAdd BLAST26
Compositional biasi573 – 634Polar residuesSequence analysisAdd BLAST62
Compositional biasi635 – 649Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi650 – 670Polar residuesSequence analysisAdd BLAST21
Compositional biasi681 – 742Polar residuesSequence analysisAdd BLAST62
Compositional biasi743 – 757Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi758 – 793Polar residuesSequence analysisAdd BLAST36
Compositional biasi800 – 831Polar residuesSequence analysisAdd BLAST32
Compositional biasi832 – 846Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi864 – 972Basic and acidic residuesSequence analysisAdd BLAST109
Compositional biasi994 – 1008Polar residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the S-100 family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S86J, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154467

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010746_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E1B971

Identification of Orthologs from Complete Genome Data

More...
OMAi
QRWSEGW

TreeFam database of animal gene trees

More...
TreeFami
TF338665

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00213, S-100, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992, EF-hand-dom_pair
IPR002048, EF_hand_dom
IPR033198, RPTN
IPR034325, S-100_dom
IPR001751, S100/CaBP-9k_CS
IPR013787, S100_Ca-bd_sub

The PANTHER Classification System

More...
PANTHERi
PTHR14054, PTHR14054, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01023, S_100, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01394, S_100, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473, SSF47473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50222, EF_HAND_2, 1 hit
PS00303, S100_CABP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E1B971-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTELLNSILT VIRVFQKYAK ENGDSTSLCK EELKQLLLAE FGDILRRPND
60 70 80 90 100
PETVETILSL LDRNRNEHVD FHEYLLMVFQ LAQACYHRLD NESYGDRTSQ
110 120 130 140 150
QERKQEGTQG HTFPTNTGRQ HRKRHEGERQ DSCHSQSEKQ SQDTHQDQSE
160 170 180 190 200
RQDRDSRYSQ SERLDRDSHY GQSEGQDRDS HYGQTERQGQ DSSSGQRLSN
210 220 230 240 250
KSGSGNPERQ GYVFALNQYE KQLQDSHCGQ SDRLGQQSSY GQSGRLREDP
260 270 280 290 300
QYSHTNQQES GSYNEQSGRL GQESGYGQRN RQELESHYGQ TDRQGLSTHC
310 320 330 340 350
SQTRPDRQGQ SYHYGQTDRQ GQSSHYGQTD RQGLSSQYGQ TDRQGLSSHY
360 370 380 390 400
GQTDRQGLSS QYGQTDRQGL SSHYGQMDRQ GQRSHYDQTD RQGLSSQYGQ
410 420 430 440 450
MDRQGLSSHY GQTDRQGLSS QYGRMDRQGQ RSHYDQTDRQ GLSSQYGQTD
460 470 480 490 500
RQGQSSHYDE TDRQGLSSHY GQTDRQGLSS QYGQTDRQGQ SSHYDETDRQ
510 520 530 540 550
DLSSHYGQTD RQGLSSQYGQ TDRQGQSSHY DETDRQGLSS HYGQTDRQGL
560 570 580 590 600
SSQYGQTDRQ GQSCHYDETD RQGLSSHYGQ TDRQGLSSQY GQTDRQGQSS
610 620 630 640 650
HYDETDGQGL SSHYGQTDRQ GLSSQYGQTD RQGQSCHYDE TDRQDLSSHY
660 670 680 690 700
GQTDRQGLSS QYGQTDRQGQ SFHYDETDRQ GLSSHYGQTD RQGQRSHYDQ
710 720 730 740 750
TDRQGLSSHY GQTDRQGLSS QYGQTDRQGL SSHYGQTDRQ GQSSHYDETD
760 770 780 790 800
RHGLSTRYSQ TDRQGVNSQY GQSETGETRQ NRCFQGSEGA SRDSHVEQSG
810 820 830 840 850
RPGRPSQYTQ GQEVNRNQGQ RFQTREGQQN SRQAWESEED SQHKLVAQIQ
860 870 880 890 900
QERPPCHSGR DWQSHSGEQG HRQETPRETW DRETHEDKQT PQRRDRQTHE
910 920 930 940 950
DQQTGQRQDR QTHEDEQTRQ RRDRQTHEDE QTHEDEQTRQ RQDRQTHEED
960 970 980 990 1000
QNRRQQQDWQ THKDKERYQE SQYRQSHGTQ EGCANREKFH MNEDGQSPSS
1010 1020 1030 1040 1050
QGRCSDLAFH PTQNAGRPQR REQGGSHPIK ATIAPNPLYD YVQEQKGVWH
Length:1,050
Mass (Da):121,412
Last modified:April 10, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4234BA86E837117B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q1M4I0A0A3Q1M4I0_BOVIN
Repetin
RPTN
1,236Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSBTAT00000056701; ENSBTAP00000052019; ENSBTAG00000039260

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000052019

Proteomic databases

PaxDbiE1B971

Genome annotation databases

EnsembliENSBTAT00000056701; ENSBTAP00000052019; ENSBTAG00000039260

Organism-specific databases

VGNCiVGNC:55674, RPTN

Phylogenomic databases

eggNOGiENOG502S86J, Eukaryota
GeneTreeiENSGT00940000154467
HOGENOMiCLU_010746_0_0_1
InParanoidiE1B971
OMAiQRWSEGW
TreeFamiTF338665

Gene expression databases

BgeeiENSBTAG00000039260, Expressed in surface of tongue and 14 other tissues

Family and domain databases

CDDicd00213, S-100, 1 hit
InterProiView protein in InterPro
IPR011992, EF-hand-dom_pair
IPR002048, EF_hand_dom
IPR033198, RPTN
IPR034325, S-100_dom
IPR001751, S100/CaBP-9k_CS
IPR013787, S100_Ca-bd_sub
PANTHERiPTHR14054, PTHR14054, 3 hits
PfamiView protein in Pfam
PF01023, S_100, 1 hit
SMARTiView protein in SMART
SM01394, S_100, 1 hit
SUPFAMiSSF47473, SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222, EF_HAND_2, 1 hit
PS00303, S100_CABP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE1B971_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1B971
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: April 10, 2019
Last modified: June 2, 2021
This is version 63 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again