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Entry version 62 (02 Jun 2021)
Sequence version 1 (02 Nov 2010)
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Protein

Voltage-dependent N-type calcium channel subunit alpha

Gene

Cacna1b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.

UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCalcium channelUniRule annotationARBA annotation, Ion channel, Voltage-gated channelUniRule annotation
Biological processCalcium transport, Ion transport, Transport
LigandCalcium, Metal-bindingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Voltage-dependent N-type calcium channel subunit alphaUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cacna1bImported
Synonyms:CACNA1BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

Rat genome database

More...
RGDi
628852, Cacna1b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei97 – 114HelicalSequence analysisAdd BLAST18
Transmembranei135 – 156HelicalSequence analysisAdd BLAST22
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Transmembranei223 – 245HelicalSequence analysisAdd BLAST23
Transmembranei300 – 321HelicalSequence analysisAdd BLAST22
Transmembranei333 – 355HelicalSequence analysisAdd BLAST23
Transmembranei485 – 505HelicalSequence analysisAdd BLAST21
Transmembranei511 – 528HelicalSequence analysisAdd BLAST18
Transmembranei549 – 567HelicalSequence analysisAdd BLAST19
Transmembranei610 – 632HelicalSequence analysisAdd BLAST23
Transmembranei688 – 710HelicalSequence analysisAdd BLAST23
Transmembranei1169 – 1187HelicalSequence analysisAdd BLAST19
Transmembranei1207 – 1227HelicalSequence analysisAdd BLAST21
Transmembranei1239 – 1257HelicalSequence analysisAdd BLAST19
Transmembranei1300 – 1322HelicalSequence analysisAdd BLAST23
Transmembranei1412 – 1437HelicalSequence analysisAdd BLAST26
Transmembranei1493 – 1511HelicalSequence analysisAdd BLAST19
Transmembranei1523 – 1549HelicalSequence analysisAdd BLAST27
Transmembranei1616 – 1634HelicalSequence analysisAdd BLAST19
Transmembranei1703 – 1726HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

GlycoproteinARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E1AW38, RN

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1742 – 1777EF-handInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 37DisorderedSequence analysisAdd BLAST37
Regioni768 – 788DisorderedSequence analysisAdd BLAST21
Regioni820 – 1041DisorderedSequence analysisAdd BLAST222
Regioni1070 – 1096DisorderedSequence analysisAdd BLAST27
Regioni1999 – 2220DisorderedSequence analysisAdd BLAST222

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili363 – 383Sequence analysisAdd BLAST21
Coiled coili713 – 739Sequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi820 – 842Basic and acidic residuesSequence analysisAdd BLAST23
Compositional biasi893 – 965Basic and acidic residuesSequence analysisAdd BLAST73
Compositional biasi986 – 1041Basic and acidic residuesSequence analysisAdd BLAST56
Compositional biasi1079 – 1096Polar residuesSequence analysisAdd BLAST18
Compositional biasi2032 – 2049Polar residuesSequence analysisAdd BLAST18
Compositional biasi2065 – 2081Basic residuesSequence analysisAdd BLAST17
Compositional biasi2112 – 2135Basic and acidic residuesSequence analysisAdd BLAST24
Compositional biasi2179 – 2220Polar residuesSequence analysisAdd BLAST42

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]UniRule annotation
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1B subfamily. [View classification]ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
HRACDER

Database of Orthologous Groups

More...
OrthoDBi
172471at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002048, EF_hand_dom
IPR031649, GPHH_dom
IPR005821, Ion_trans_dom
IPR014873, VDCC_a1su_IQ
IPR005447, VDCC_N_a1su
IPR002077, VDCCAlpha1
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10037, PTHR10037, 1 hit
PTHR10037:SF289, PTHR10037:SF289, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08763, Ca_chan_IQ, 1 hit
PF16905, GPHH, 1 hit
PF00520, Ion_trans, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00167, CACHANNEL
PR01631, NVDCCALPHA1

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01062, Ca_chan_IQ, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50222, EF_HAND_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E1AW38-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVRFGDELGG RYGGTGGGER ARGGGAGGAG GPGQGGLPPG QRVLYKQSIA
60 70 80 90 100
QRARTMALYN PIPVKQNCFT VNRSLFVFSE DNVVRKYAKR ITEWPPFEYM
110 120 130 140 150
ILATIIANCI VLALEQHLPD GDKTPMSERL DDTEPYFIGI FCFEAGIKII
160 170 180 190 200
ALGFVFHKGS YLRNGWNVMD FVVVLTGILA TAGTDFDLRT LRAVRVLRPL
210 220 230 240 250
KLVSGIPSLQ VVLKSIMKAM VPLLQIGLLL FFAILMFAII GLEFYMGKFH
260 270 280 290 300
KACFPNSTDA EPVGDFPCGK EAPARLCDSD TECREYWPGP NFGITNFDNI
310 320 330 340 350
LFAILTVFQC ITMEGWTDIL YNTNDAAGNT WNWLYFIPLI IIGSFFMLNL
360 370 380 390 400
VLGVLSGEFA KERERVENRR AFLKLRRQQQ IERELNGYLE WIFKAEEVML
410 420 430 440 450
AEEDKNAEEK SPLDAVLKRA ATKKSRNDLI HAEEGEDRFV DLCAAGSPFA
460 470 480 490 500
RASLKSGKTE SSSYFRRKEK MFRFLIRRMV KAQSFYWVVL CVVALNTLCV
510 520 530 540 550
AMVHYNQPQR LTTALYFAEF VFLGLFLTEM SLKMYGLGPR SYFRSSFNCF
560 570 580 590 600
DFGVIVGSIF EVVWAAIKPG TSFGISVLRA LRLLRIFKVT KYWNSLRNLV
610 620 630 640 650
VSLLNSMKSI ISLLFLLFLF IVVFALLGMQ LFGGQFNFQD ETPTTNFDTF
660 670 680 690 700
PAAILTVFQI LTGEDWNAVM YHGIESQGGV SKGMFSSFYF IVLTLFGNYT
710 720 730 740 750
LLNVFLAIAV DNLANAQELT KDEEEMEEAA NQKLALQKAK EVAEVSPMSA
760 770 780 790 800
ANISIAAFVK QTRGTVSRSS SVSSVNSPQQ NSAKARSVWE QRASQLRLQN
810 820 830 840 850
LRASCEALYS EMDPEERLRY ASTRHVRPDM KTHMDRPLVV EPGRDGLRGP
860 870 880 890 900
AGNKSKPEGT EATEGADPPR RHHRHRDRDK TSASTPAGGE QDRTDCPKAE
910 920 930 940 950
STETGAREER ARPRRSHSKE APGADTQVRC ERSRRHHRRG SPEEATEREP
960 970 980 990 1000
RRHRAHRHAQ DSSKEGKEGT APVLVPKGER RARHRGPRTG PRETENSEEP
1010 1020 1030 1040 1050
TRRHRAKHKV PPTLEPPERE VAEKESNVVE GDKETRNHQP KEPRCDLEAI
1060 1070 1080 1090 1100
AVTGVGSLHM LPSTCLQKVD EQPEDADNQR NVTRMGSQPS DPSTTVHVPV
1110 1120 1130 1140 1150
TLTGPPGEAT VVPSANTDLE GQAEGKKEAE ADDVLRRGPR PIVPYSSMFC
1160 1170 1180 1190 1200
LSPTNLLRRF CHYIVTMRYF EMVILVVIAL SSIALAAEDP VRTDSFRNNA
1210 1220 1230 1240 1250
LKYMDYIFTG VFTFEMVIKM IDLGLLLHPG AYFRDLWNIL DFIVVSGALV
1260 1270 1280 1290 1300
AFAFSGSKGK DINTIKSLRV LRVLRPLKTI KRLPKLKAVF DCVVNSLKNV
1310 1320 1330 1340 1350
LNILIVYMLF MFIFAVIAVQ LFKGKFFYCT DESKELERDC RGQYLDYEKE
1360 1370 1380 1390 1400
EVEAQPRQWK KYDFHYDNVL WALLTLFTVS TGEGWPMVLK HSVDATYEEQ
1410 1420 1430 1440 1450
GPSPGFRMEL SIFYVVYFVV FPFFFVNIFV ALIIITFQEQ GDKVMSECSL
1460 1470 1480 1490 1500
EKNERACIDF AISAKPLTRY MPQNKQSFQY KTWTFVVSPP FEYFIMAMIA
1510 1520 1530 1540 1550
LNTVVLMMKF YDAPYEYELM LKCLNIVFTS MFSLECILKI IAFGVLNYFR
1560 1570 1580 1590 1600
DAWNVFDFVT VLGSITDILV TEIAETNNFI NLSFLRLFRA ARLIKLLRQG
1610 1620 1630 1640 1650
YTIRILLWTF VQSFKALPYV CLLIAMLFFI YAIIGMQVFG NIALDDGTSI
1660 1670 1680 1690 1700
NRHNNFRTFL QALMLLFRSA TGEAWHEIML SCLGNRACDP HANASECGSD
1710 1720 1730 1740 1750
FAYFYFVSFI FLCSFLMLNL FVAVIMDNFE YLTRDSSILG PHHLDEFIRV
1760 1770 1780 1790 1800
WAEYDPAACG RISYNDMFEM LKHMSPPLGL GKKCPARVAY KRLVRMNMPI
1810 1820 1830 1840 1850
SNEDMTVHFT STLMALIRTA LEIKLAPAGT KQHQCDAELR KEISSVWANL
1860 1870 1880 1890 1900
PQKTLDLLVP PHKPDEMTVG KVYAALMIFD FYKQNKTTRD QTHQAPGGLS
1910 1920 1930 1940 1950
QMGPVSLFHP LKATLEQTQP AVLRGARVFL RQKSATSLSN GGAIQTQESG
1960 1970 1980 1990 2000
IKESLSWGTQ RTQDVLYEAR APLERGHSAE IPVGQPGALA VDVQMQNMTL
2010 2020 2030 2040 2050
RGPDGEPQPG LESQGRAASM PRLAAETQPA PNASPMKRSI STLAPRPHGT
2060 2070 2080 2090 2100
QLCNTVLDRP PPSQVSHHHH HRCHRRRDKK QRSLEKGPSL SVDTEGAPST
2110 2120 2130 2140 2150
AAGSGLPHGE GSTGCRRERK QERGRSQERR QPSSSSSEKQ RFYSCDRFGS
2160 2170 2180 2190 2200
REPPQPKPSL SSHPISPTAA LEPGPHPQGS GSVNGSPLMS TSGASTPGRG
2210 2220 2230 2240 2250
GRRQLPQTPL TPRPSITYKT ANSSPVHFAE GQSGLPAFSP GRLSRGLSEH
2260 2270 2280 2290 2300
NALLQKEPLS QPLASGSRIG SDPYLGQRLD SEASAHNLPE DTLTFEEAVA
2310 2320 2330 2340 2350
TNSGRSSRTS YVSSLTSQSH PLRRVPNGYH CTLGLSTGVR ARHSYHHPDQ

DHWC
Length:2,354
Mass (Da):264,038
Last modified:November 2, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i654FE099A67FF015
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HQ008360 mRNA Translation: ADM13675.1

NCBI Reference Sequences

More...
RefSeqi
NP_001182128.1, NM_001195199.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
257648

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:257648

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ008360 mRNA Translation: ADM13675.1
RefSeqiNP_001182128.1, NM_001195199.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi257648
KEGGirno:257648

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
774
RGDi628852, Cacna1b

Phylogenomic databases

OMAiHRACDER
OrthoDBi172471at2759

Gene expression databases

GenevisibleiE1AW38, RN

Family and domain databases

Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR002048, EF_hand_dom
IPR031649, GPHH_dom
IPR005821, Ion_trans_dom
IPR014873, VDCC_a1su_IQ
IPR005447, VDCC_N_a1su
IPR002077, VDCCAlpha1
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf
PANTHERiPTHR10037, PTHR10037, 1 hit
PTHR10037:SF289, PTHR10037:SF289, 1 hit
PfamiView protein in Pfam
PF08763, Ca_chan_IQ, 1 hit
PF16905, GPHH, 1 hit
PF00520, Ion_trans, 4 hits
PRINTSiPR00167, CACHANNEL
PR01631, NVDCCALPHA1
SMARTiView protein in SMART
SM01062, Ca_chan_IQ, 1 hit
PROSITEiView protein in PROSITE
PS50222, EF_HAND_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE1AW38_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E1AW38
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: June 2, 2021
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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