Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - E0VZS5 (E0VZS5_PEDHC)

Entry version 58 (10 Feb 2021)
Sequence version 1 (02 Nov 2010)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Transcription initiation factor TFIID subunit, putative

Gene

Phum_PHUM537630

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionInitiation factorImported
Biological processProtein biosynthesis, Transcription, Transcription regulationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transcription initiation factor TFIID subunit, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:Phum_PHUM537630Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPediculus humanus subsp. corporis (Body louse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri121224 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Paraneoptera › Psocodea › Phthiraptera › Anoplura › Pediculidae › Pediculus ›

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		121225.PHUM537630-PA

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini400 – 496TAFHInterPro annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni564 – 615DisorderedSequence analysisAdd BLAST52
Regioni853 – 885DisorderedSequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi564 – 591PolarSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TAF4 family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2341, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_012027_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		E0VZS5

Identification of Orthologs from Complete Genome Data

More...OMAi		CKNFLSM

Database for complete collections of gene phylogenies

More...PhylomeDBi		E0VZS5

Family and domain databases

Conserved Domains Database

More...CDDi		cd08045, TAF4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.20.10, 1 hit
1.20.120.1110, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR009072, Histone-fold
IPR007900, TAF4
IPR037249, TAFH/NHR1_dom_sf
IPR003894, TAFH_NHR1

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05236, TAF4, 1 hit
PF07531, TAFH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00549, TAFH, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF158553, SSF158553, 1 hit
SSF47113, SSF47113, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51119, TAFH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E0VZS5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASTQFLEEA LSTDVDESAV NALVGSLETQ LVPPTSVQSN ADGKVVQNHV 
        60         70         80         90        100
NNTISNGGIV QKHGVSNEES EGLVNNAGGV IPDGNSNTKQ TLVRSTSLAH 
       110        120        130        140        150
SAVVNTVVTS LSGLPISQIG PNVITKSSDG VKIVTYPAGN QLGSPQVVNI 
       160        170        180        190        200
NNRVSFPQTI TLPNGSIPSS VISSVPSNVQ TIVTNSPLNK SLPGAINVIK 
       210        220        230        240        250
VDQGQPSGAT LVIKTPGSGP MTAGSMTLTQ GTPGTTAAPG IVTLAKPLMA 
       260        270        280        290        300
GQSVGNTVQI LNVNAVRPGT PIQGQKGLPQ HRVVINSPQV ISRPGAPNQP 
       310        320        330        340        350
TQITLSPLQG LQPGGSGHIL VKSESGQLQL IRIGPAPTAT PGAPSGTIAS 
       360        370        380        390        400
NNASQFRIQS LPVQQGSGST AAVVIATSTA GSIQSSQPPG LTATTPKQQM 
       410        420        430        440        450
DTTKEKCRKF LANLLELSSR EPKAVERNVR TLIQELIDAK VEPEDFCDRL 
       460        470        480        490        500
EKLLNASPQP CLIGFLKKSL PLLRQSLFSR EMTIEGIRPP PQQVVSTTAS 
       510        520        530        540        550
VAQVPQMQAQ LRPQMVTQTV RVVAPLNAAG QNISVTTPRM GTLQNRGQIP 
       560        570        580        590        600
AQGKIIATSI RGQTPLATST QPPPLHHTTP ISSQTPSSPP VHQIRPTTPA 
       610        620        630        640        650
RAAAPKNQTT KTPVKQVITK TTVQTKSNAN NSRSINVIAK PSTPSVTNKS 
       660        670        680        690        700
ISKVISKGGY EELKFGATSF SGDDDINDVA AMGGVNLAEE SQRILGSTQF 
       710        720        730        740        750
VGTQIRSVKD EIFLHSIPLQ NKIRQIVSNH GLDEPSSEVA SLVSHACQER 
       760        770        780        790        800
LKTLIEKLAC IAEHRIDVIK LDSRYEVVQD VKGQLKFLEE LDRVERKRHE 
       810        820        830        840        850
EQERELLLRA AKSRSKSEDP EQVKLKAKAK EMQRAEMEEL RQREANLTAL 
       860        870        880        890        900
QAIGPRKKPR LDGPGNSGDA SGTGSSGTLF GRPHLPLRPR LKRVNLKDLL 
       910        920 
FLLEQEKETS KTNLLYKAYL K
Length:921
Mass (Da):98,039
Last modified:November 2, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAFB305E1AA811175
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
DS235854 Genomic DNA Translation: EEB18881.1

NCBI Reference Sequences

More...RefSeqi		XP_002431619.1, XM_002431574.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		8235436

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		phu:Phum_PHUM537630

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235854 Genomic DNA Translation: EEB18881.1
RefSeqiXP_002431619.1, XM_002431574.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi121225.PHUM537630-PA

Genome annotation databases

GeneIDi8235436
KEGGiphu:Phum_PHUM537630

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		8235436

Phylogenomic databases

eggNOGiKOG2341, Eukaryota
HOGENOMiCLU_012027_0_0_1
InParanoidiE0VZS5
OMAiCKNFLSM
PhylomeDBiE0VZS5

Family and domain databases

CDDicd08045, TAF4, 1 hit
Gene3Di1.10.20.10, 1 hit
1.20.120.1110, 1 hit
InterProiView protein in InterPro
IPR009072, Histone-fold
IPR007900, TAF4
IPR037249, TAFH/NHR1_dom_sf
IPR003894, TAFH_NHR1
PfamiView protein in Pfam
PF05236, TAF4, 1 hit
PF07531, TAFH, 1 hit
SMARTiView protein in SMART
SM00549, TAFH, 1 hit
SUPFAMiSSF158553, SSF158553, 1 hit
SSF47113, SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS51119, TAFH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE0VZS5_PEDHC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E0VZS5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: February 10, 2021
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again