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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotationSAAS annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotationSAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationSAAS annotationImported, Transferase
Biological processCell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciDDAD198628:DDA3937_RS18040-MONOMER
UniPathwayi
UPA00219

Protein family/group databases

CAZyiGT28 Glycosyltransferase Family 28

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationSAAS annotation (EC:2.4.1.227UniRule annotationSAAS annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotationImported
Ordered Locus Names:Dda3937_02438Imported
OrganismiDickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))Imported
Taxonomic identifieri198628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaeDickeya
Proteomesi
  • UP000006859 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Interactioni

Protein-protein interaction databases

STRINGi198628.Dda3937_02438

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 145Glyco_transf_28InterPro annotationAdd BLAST137
Domaini185 – 342Glyco_tran_28_CInterPro annotationAdd BLAST158

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
HOGENOMiHOG000218321
KOiK02563
OMAiHQTKNAM
OrthoDBiPOG091H02FX

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit

Sequencei

Sequence statusi: Complete.

E0SG75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGEGKRLMV MAGGTGGHVF PGLAVAHHLM AQGWQVRWLG TADRMEADLV
60 70 80 90 100
PKHGIDIDFI RISGLRGKGL TALLLAPVRI FRAVRQAQAI MRRYQPDVVL
110 120 130 140 150
GMGGYVSGPG GLAAWLCGIP VVLHEQNGIA GLTNRWLSRI AKKVLQAFPG
160 170 180 190 200
AFPHADVVGN PVRTDVLALP SPTERLADRS GPVRVLVVGG SQGARVLNQT
210 220 230 240 250
LPGVAARLHD AVTIWHQTGK GAQAEVQAAY AQAGQPQHRI TEFIDDMAAA
260 270 280 290 300
YAWADVVVCR SGALTVSEIA AAGLPALFVP FQHKDRQQYW NALPLERAGA
310 320 330 340 350
AKIIEQADLS VDTISEVLAA WERATLRDMA QKARTVAIPD ATERVAAEVA
360
AAAMQRAVHA VRN
Length:363
Mass (Da):38,762
Last modified:November 2, 2010 - v1
Checksum:i30BB51C1CC92AA82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002038 Genomic DNA Translation: ADN00043.1
RefSeqiWP_013319464.1, NC_014500.1

Genome annotation databases

EnsemblBacteriaiADN00043; ADN00043; Dda3937_02438
GeneIDi9735322
KEGGiddd:Dda3937_02438
PATRICifig|198628.6.peg.3787

Similar proteinsi

Entry informationi

Entry nameiE0SG75_DICD3
AccessioniPrimary (citable) accession number: E0SG75
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: June 20, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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