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Protein
Submitted name:

Versican core protein

Gene

Vcan

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-1971475 A tetrasaccharide linker sequence is required for GAG synthesis
R-MMU-2022870 Chondroitin sulfate biosynthesis
R-MMU-2022923 Dermatan sulfate biosynthesis
R-MMU-2024101 CS/DS degradation
R-MMU-3000178 ECM proteoglycans
R-MMU-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275 Post-translational protein phosphorylation

Names & Taxonomyi

Protein namesi
Submitted name:
Versican core proteinImported
Gene namesi
Name:VcanImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:102889 Vcan

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500313331321 – 100Sequence analysisAdd BLAST80

Proteomic databases

MaxQBiE0CZC0
PeptideAtlasiE0CZC0
PRIDEiE0CZC0

Expressioni

Gene expression databases

BgeeiENSMUSG00000021614 Expressed in 280 organ(s), highest expression level in ureter smooth muscle
ExpressionAtlasiE0CZC0 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 100IGvInterPro annotationAdd BLAST74

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFXS Eukaryota
ENOG410ZPDG LUCA
GeneTreeiENSGT00760000119025
OMAiRENKTGR

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

E0CZC0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLINMKGILW MCSTLLLTHA LHQAKMETSP PVKGSLSGKV VLPCHFSTLP
60 70 80 90 100
TLPPNYNTSE FLRIKWSKME VDKNGKDIKE TTVLVAQNGN IKIGQDYKGR
Length:100
Mass (Da):11,183
Last modified:October 5, 2010 - v1
Checksum:iFFA39C4824D1BE00
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q62059CSPG2_MOUSE
Versican core protein
Vcan Cspg2
3,357Annotation score:
E9PYH0E9PYH0_MOUSE
Versican core protein
Vcan
3,354Annotation score:
E9QMK3E9QMK3_MOUSE
Versican core protein
Vcan
655Annotation score:
E9QMK2E9QMK2_MOUSE
Versican core protein
Vcan
1,615Annotation score:
Q8BS97Q8BS97_MOUSE
Versican core protein
Vcan Cspg2
368Annotation score:
G3XA35G3XA35_MOUSE
MCG116562, isoform CRA_a
Vcan mCG_116562
2,394Annotation score:
F7B603F7B603_MOUSE
Versican core protein
Vcan
141Annotation score:
F7B6F7F7B6F7_MOUSE
Versican core protein
Vcan
98Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei100Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134397 Genomic DNA No translation available.
AC154460 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000162715; ENSMUSP00000125521; ENSMUSG00000021614

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134397 Genomic DNA No translation available.
AC154460 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE0CZC0
PeptideAtlasiE0CZC0
PRIDEiE0CZC0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000162715; ENSMUSP00000125521; ENSMUSG00000021614

Organism-specific databases

MGIiMGI:102889 Vcan

Phylogenomic databases

eggNOGiENOG410IFXS Eukaryota
ENOG410ZPDG LUCA
GeneTreeiENSGT00760000119025
OMAiRENKTGR

Enzyme and pathway databases

ReactomeiR-MMU-1971475 A tetrasaccharide linker sequence is required for GAG synthesis
R-MMU-2022870 Chondroitin sulfate biosynthesis
R-MMU-2022923 Dermatan sulfate biosynthesis
R-MMU-2024101 CS/DS degradation
R-MMU-3000178 ECM proteoglycans
R-MMU-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275 Post-translational protein phosphorylation

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021614 Expressed in 280 organ(s), highest expression level in ureter smooth muscle
ExpressionAtlasiE0CZC0 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE0CZC0_MOUSE
AccessioniPrimary (citable) accession number: E0CZC0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: November 7, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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