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Entry version 58 (12 Aug 2020)
Sequence version 1 (05 Oct 2010)
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Protein
Submitted name:

Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)

Gene

Galf_1153

Organism
Gallionella capsiferriformans (strain ES-2) (Gallionella ferruginea capsiferriformans (strain ES-2))
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Galf_1153Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallionella capsiferriformans (strain ES-2) (Gallionella ferruginea capsiferriformans (strain ES-2))Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri395494 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesGallionellaceaeGallionella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001235 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei21 – 41HelicalSequence analysisAdd BLAST21
Transmembranei47 – 68HelicalSequence analysisAdd BLAST22
Transmembranei88 – 107HelicalSequence analysisAdd BLAST20
Transmembranei113 – 131HelicalSequence analysisAdd BLAST19
Transmembranei138 – 157HelicalSequence analysisAdd BLAST20
Transmembranei163 – 184HelicalSequence analysisAdd BLAST22

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
395494.Galf_1153

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini208 – 252PASInterPro annotationAdd BLAST45
Domaini335 – 387PASInterPro annotationAdd BLAST53
Domaini404 – 461PACInterPro annotationAdd BLAST58
Domaini457 – 503PASInterPro annotationAdd BLAST47
Domaini530 – 582PACInterPro annotationAdd BLAST53
Domaini614 – 752GGDEFInterPro annotationAdd BLAST139
Domaini761 – 1013EALInterPro annotationAdd BLAST253

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili754 – 774Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG2202, Bacteria
COG5001, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000445_70_20_4

Identification of Orthologs from Complete Genome Data

More...
OMAi
RINQNIC

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01948, EAL, 1 hit
cd01949, GGDEF, 1 hit
cd00130, PAS, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.450, 1 hit
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001633, EAL_dom
IPR035919, EAL_sf
IPR000160, GGDEF_dom
IPR029787, Nucleotide_cyclase
IPR001610, PAC
IPR000014, PAS
IPR000700, PAS-assoc_C
IPR035965, PAS-like_dom_sf
IPR013656, PAS_4
IPR043128, Rev_trsase/Diguanyl_cyclase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00563, EAL, 1 hit
PF00990, GGDEF, 1 hit
PF08448, PAS_4, 2 hits
PF13426, PAS_9, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00052, EAL, 1 hit
SM00267, GGDEF, 1 hit
SM00086, PAC, 3 hits
SM00091, PAS, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141868, SSF141868, 1 hit
SSF55073, SSF55073, 1 hit
SSF55785, SSF55785, 3 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00254, GGDEF, 1 hit
TIGR00229, sensory_box, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50883, EAL, 1 hit
PS50887, GGDEF, 1 hit
PS50113, PAC, 2 hits
PS50112, PAS, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D9SF84-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHVKYDTSIL KSEQTRNLFA THIPSLTASM LLAIILVYIQ WDVVSHDVLV
60 70 80 90 100
GWLILLEAVQ LARMALVVRY QRNATVAEEV ISARLMRFRF GVLVSGVIWG
110 120 130 140 150
GASFLLFPQE NLPHQMFLIF MLAGLTTASV VSYSADLVSA VIFALSIVTP
160 170 180 190 200
LIARLLIVSD ELAMAMAIAV LLYLGFLMVS LRLINRNLIE NIRMRHEGEL
210 220 230 240 250
REAAMNVSKE RYRLLLAHSP VGIFHYDLNF VITYCNARFA ELIGCPVAQV
260 270 280 290 300
NGLDLYNLSD NAVLPALTAA LAGDRGYFEG QYQAVFNDGW IAMTCAASCD
310 320 330 340 350
ARGNVIGGIA IVESIHERKM AEMALALSNQ KHDEERKLFQ TILDNLPLGM
360 370 380 390 400
WMLGVDGKIK FVNETFCNAL GIAAHDFFDA GHYSDLLPLS IADKCKESDR
410 420 430 440 450
ACFMQGEPHY STEWLPFTDG RAHLLEMTRV RLHDSANNVT GLIGLAADIT
460 470 480 490 500
ERQKVESELR IAAAAFEAQE GMLITDRHNV IMRVNQAFTS ITGYLAEEVL
510 520 530 540 550
GKNPCFLASG RHDAGFYQSM WEGLNEKGKW EGEVWNRRKD GEIYPEYLLI
560 570 580 590 600
SAVKDIKNEV ANYVATFRDI TANKAAESEI KKLAFYDPLT LLPNRRLLTD
610 620 630 640 650
RLNHALASSA RNRNIGALLF IDLDNFKTLN DTLGHDMGDA LLKQVALRLK
660 670 680 690 700
SCIREDDTLA RLGGDEFVVI LENLSELAMD AATKAELIGE KILAALNQVY
710 720 730 740 750
PLASQEYHGA ASIGVTLFAG HALSIDELMK QADIAMYQSK KSGRNTLRFF
760 770 780 790 800
DLDTQKIINE RAELEIELRK AVDKKQLHLH YQIQLNSVGT PLSAEALIRW
810 820 830 840 850
VHPVRGLISP AHFIPLAEDT GLILPIGQWV LDTACAQLHS WQDERFTQDL
860 870 880 890 900
TLAVNVSAKQ FHQKNFVALV KETVQRHAIN PKLLKLELTE SMLVENIEDI
910 920 930 940 950
IVTMNALREM GIQFSLDDFG TGYSSLQYLK RLPLNQLKID QSFVRELSSS
960 970 980 990 1000
SSDRAIVRTI VAMAESLNLN VIAEGVETEE QHTLLQDIGC NYYQGYLFGK
1010
PMPIEQLDAI LAR
Length:1,013
Mass (Da):113,218
Last modified:October 5, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBFA84C6526457C17
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP002159 Genomic DNA Translation: ADL55181.1

NCBI Reference Sequences

More...
RefSeqi
WP_013293120.1, NC_014394.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ADL55181; ADL55181; Galf_1153

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gca:Galf_1153

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002159 Genomic DNA Translation: ADL55181.1
RefSeqiWP_013293120.1, NC_014394.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi395494.Galf_1153

Genome annotation databases

EnsemblBacteriaiADL55181; ADL55181; Galf_1153
KEGGigca:Galf_1153

Phylogenomic databases

eggNOGiCOG2202, Bacteria
COG5001, Bacteria
HOGENOMiCLU_000445_70_20_4
OMAiRINQNIC

Family and domain databases

CDDicd01948, EAL, 1 hit
cd01949, GGDEF, 1 hit
cd00130, PAS, 3 hits
Gene3Di3.20.20.450, 1 hit
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR001633, EAL_dom
IPR035919, EAL_sf
IPR000160, GGDEF_dom
IPR029787, Nucleotide_cyclase
IPR001610, PAC
IPR000014, PAS
IPR000700, PAS-assoc_C
IPR035965, PAS-like_dom_sf
IPR013656, PAS_4
IPR043128, Rev_trsase/Diguanyl_cyclase
PfamiView protein in Pfam
PF00563, EAL, 1 hit
PF00990, GGDEF, 1 hit
PF08448, PAS_4, 2 hits
PF13426, PAS_9, 1 hit
SMARTiView protein in SMART
SM00052, EAL, 1 hit
SM00267, GGDEF, 1 hit
SM00086, PAC, 3 hits
SM00091, PAS, 3 hits
SUPFAMiSSF141868, SSF141868, 1 hit
SSF55073, SSF55073, 1 hit
SSF55785, SSF55785, 3 hits
TIGRFAMsiTIGR00254, GGDEF, 1 hit
TIGR00229, sensory_box, 3 hits
PROSITEiView protein in PROSITE
PS50883, EAL, 1 hit
PS50887, GGDEF, 1 hit
PS50113, PAC, 2 hits
PS50112, PAS, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD9SF84_GALCS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D9SF84
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: August 12, 2020
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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