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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Corynebacterium pseudotuberculosis (strain C231)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei60NucleophileUniRule annotation1
Binding sitei126SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotation
Biological processtRNA processingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCPSE681645:G1GMB-406-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotationImported
Ordered Locus Names:CpC231_0398Imported
OrganismiCorynebacterium pseudotuberculosis (strain C231)Imported
Taxonomic identifieri681645 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000000276 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 82PseudoU_synth_1InterPro annotationAdd BLAST68
Domaini160 – 266PseudoU_synth_1InterPro annotationAdd BLAST107

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 2 hits
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

D9QEG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METNQPTVRI RLDLAYDGTH FHGWARQGTS QLRTVQRVLE DSLELILRHP
60 70 80 90 100
IQLTVAGRTD AGVHAAGQVA HFDVPAIALD TRSIDGDPRN LVRRLARLLP
110 120 130 140 150
EDVRVHACTL APEGFDARFS ALRRHYVYRL TTHPRGALPT RATDTAHWPK
160 170 180 190 200
RIDIDAMQAA ADVLIGLHDF AAFCKHREGA TTIRDLQEFT WHDVSTSLEP
210 220 230 240 250
QLYEAHVTAD AFCWSMVRSL VGSCLVIGEG KRPEGFVDSL LTETSRSSQV
260 270 280 290
PVAPAKGLSL VGVDYPVDSE LLARANTTRA VRTAEDISGN L
Length:291
Mass (Da):32,139
Last modified:October 5, 2010 - v1
Checksum:i1F7CBEB6E6314D0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001829 Genomic DNA Translation: ADL09888.1
RefSeqiWP_013241251.1, NC_017301.1

Genome annotation databases

EnsemblBacteriaiADL09888; ADL09888; CpC231_0398
GeneIDi12298136
KEGGicpq:CpC231_0398
PATRICifig|681645.3.peg.416

Similar proteinsi

Entry informationi

Entry nameiD9QEG5_CORP2
AccessioniPrimary (citable) accession number: D9QEG5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: July 18, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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