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Entry version 24 (12 Aug 2020)
Sequence version 1 (05 Oct 2010)
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Protein
Submitted name:

Epiglycanin

Gene

Gm9573

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
EpiglycaninImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gm9573Imported
Synonyms:Muc21Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3779983, Gm9573

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1536 – 1558HelicalSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500312585225 – 1608Sequence analysisAdd BLAST1584

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
138, 6 O-Linked glycans

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1520 – 1580Epiglycanin_CInterPro annotationAdd BLAST61

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni26 – 1416DisorderedSequence analysisAdd BLAST1391
Regioni1464 – 1525DisorderedSequence analysisAdd BLAST62

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1464 – 1523PolarSequence analysisAdd BLAST60

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033534, MUC21
IPR028199, Mucin_dom

The PANTHER Classification System

More...
PANTHERi
PTHR39408, PTHR39408, 11 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14654, Epiglycanin_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D9N008-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRRSSLWCW LLLQILLLGS XXYAHISSTT TSNPSSETKS IATDYETTPT
60 70 80 90 100
TTISSTASGS MPTLTTKASS IASDSKPTLT TTASSTASGS MSTPTTPASS
110 120 130 140 150
TASGSTPTTT TTASSTASGS TPTPTTPASS TASGSTPTPT TTASSKASRS
160 170 180 190 200
VPTTVSSTGS GSTPTPTTTA SSTASGSTPT LTTTPSSTAS GSTPTPTTPA
210 220 230 240 250
SSTASGSSPT PTTPVSSTAS GSTPTPTTTA SSKASGSVPT TVSSTGSGST
260 270 280 290 300
PTLTTTVSST VSDSTPTPTT TASSTASGSA PTPTTTASST ASGSTPTLTT
310 320 330 340 350
TASSSGSGST PTLPTTESST ASGSTPTRTT TTSSTASRST PTPTTTASST
360 370 380 390 400
ASGSTPTPTT TVSSTGSGST PTLTTTASRS GSGSTPTLTT TESSTASGSS
410 420 430 440 450
PTLTTTASSS ASGSMPTPTT TASSTASGSS PTLTTTASSS ASGSMPTLTT
460 470 480 490 500
TASSSASGSS PTLTTTASSS ASGSMPTPTT TVSSTGSGST PTLTTTESST
510 520 530 540 550
ASGSTPTWTT TTSSTASRST PTPTTTASST ASGSTPTPTT TVSSTGSGST
560 570 580 590 600
PTLTTTASRS GSGSTPTLTT TESSTASGSI PTLTTAASST ASGSTPTPTT
610 620 630 640 650
TASSTASGSM PTPTTTASST GSGSTPTLTT TASSSGSGST PTLTTTESST
660 670 680 690 700
ASGSIPTLTS AASSSASGSM PTPTTTVSST GSGSTPTLTT TASSSASGSM
710 720 730 740 750
PTPTTTASST ASGSSPTLTT TASSSASGSA PNPTTTVSST GSGSTPTLTT
760 770 780 790 800
TASSSGSGST PTLPTTESST ASGSTPTRTT TTSSTASRST PTPTTTASST
810 820 830 840 850
ASGSTPTPTT TVSSTASGST PTLTTTASRS GSGSTPTLTT TESSTASGST
860 870 880 890 900
PTPTTTASST ASGSAPNPTT TVSSTASGST PTLPTTASSS GSGSTPTLTT
910 920 930 940 950
TESSTASGSS PTLTTTASSS ASGSMPTPTT TASSTASGSS PTLTTTASSS
960 970 980 990 1000
ASGSMPTLTT TASSSASGSS PTLTTTASSS ASGSMPTPTT TVSSTGSGST
1010 1020 1030 1040 1050
PTLTTTESST ASGSTPTWTT TTSSTASRST PTPTTTASST ASGSTPTPTT
1060 1070 1080 1090 1100
TVSSTGSGST PTLTTTASRR GSGSTPTLTT TESSTGSGST PTLTTTASSS
1110 1120 1130 1140 1150
GSGSTPTLPT TESSTASGST PTRTTTTSST ASRSTPTPTT TASSTASGST
1160 1170 1180 1190 1200
PTPTTTVSST ASGSTPTLTT TASRSGSGST PILTTTESST ASGSTPTLTT
1210 1220 1230 1240 1250
AASSSASGST PTPTTTVSST GSGSTPTLTT TASSSGSGST PTLTTTESST
1260 1270 1280 1290 1300
ASGSTPTQTT TTSSTASRST PTPTTTASST ASGSIPTPTT TASSIASGTT
1310 1320 1330 1340 1350
PTLTTTESST ASGSSPTPTT ASSSSASDSK PTSTTTASST VSDSTPTPTT
1360 1370 1380 1390 1400
NASSSASGST PTQTTTASRS ASGSVPTLTT IAFSTASGST PTLTTTASNS
1410 1420 1430 1440 1450
ASSSSPTPTT TGLSKTSASS LSLTSTMTSI TSASTFTPAS IRTSKASAST
1460 1470 1480 1490 1500
STSASIRTSI AFASTSTPTT SGPSTASVST LNSTSIRTST GSSSSLSATH
1510 1520 1530 1540 1550
TSSSLTVSTG THTTSNHTGT PVMEVKPSGS LKPWEIFLIT LASVIVVMGL
1560 1570 1580 1590 1600
SAGLFIYVXR RYLSLRNAAD GIFYNSHPDP GGSAMTPGSL TCSWRRPRTF

NVVEMTRI
Length:1,608
Mass (Da):151,961
Last modified:October 5, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i92C8A1EC43ABD51A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HM596785 mRNA Translation: ADJ96648.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM596785 mRNA Translation: ADJ96648.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

PTM databases

GlyConnecti138, 6 O-Linked glycans

Organism-specific databases

MGIiMGI:3779983, Gm9573

Miscellaneous databases

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR033534, MUC21
IPR028199, Mucin_dom
PANTHERiPTHR39408, PTHR39408, 11 hits
PfamiView protein in Pfam
PF14654, Epiglycanin_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD9N008_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D9N008
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: August 12, 2020
This is version 24 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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