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UniProtKB - D9J2V6 (D9J2V6_MOUSE)
Protein
Submitted name:
Pre-B-cell leukemia transcription factor 1
Gene
Pbx1
Organism
Mus musculus (Mouse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 233 – 281 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 49 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Pre-B-cell leukemia transcription factor 1ImportedSubmitted name: Pre-B-cell leukemia transcription factor 1dImported |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:97495, Pbx1 |
VEuPathDBi | HostDB:ENSMUSG00000052534 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotationARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000052534, Expressed in rostral migratory stream and 311 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 231 – 280 | HomeoboxInterPro annotationAdd BLAST | 50 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 40 | DisorderedSequence analysisAdd BLAST | 40 | |
Regioni | 308 – 339 | DisorderedSequence analysisAdd BLAST | 32 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 165 – 185 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the TALE/PBX homeobox family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000154374 |
OrthoDBi | 804740at2759 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR005542, PBX |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF03792, PBC, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS50071, HOMEOBOX_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
D9J2V6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI
60 70 80 90 100
MTITDQSLDE AQARKHALNC HRMKPALFNV LCEIKEKTVL SIRGAQEEEP
110 120 130 140 150
TDPQLMRLDN MLLAEGVAGP EKGGGSAAAA AAAAASGGAG SDNSVEHSDY
160 170 180 190 200
RAKLSQIRQI YHTELEKYEQ ACNEFTTHVM NLLREQSRTR PISPKEIERM
210 220 230 240 250
VSIIHRKFSS IQMQLKQSTC EAVMILRSRF LDARRKRRNF NKQATEILNE
260 270 280 290 300
YFYSHLSNPY PSEEAKEELA KKCGITVSQV DTLRHVISQT GGYSDGLAAS
310 320 330
QMYSPQGISA NGGWQDATTP SSVTSPTEGP GSVHSDTSN
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketP41778 | PBX1_MOUSE | Pre-B-cell leukemia transcription f... | Pbx1 Pbx-1 | 430 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HM369110 mRNA Translation: ADK11716.1 |
RefSeqi | NP_001278438.1, NM_001291509.1 |
Genome annotation databases
Ensembli | ENSMUST00000064438; ENSMUSP00000066385; ENSMUSG00000052534 |
GeneIDi | 18514 |
UCSCi | uc007dlg.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HM369110 mRNA Translation: ADK11716.1 |
RefSeqi | NP_001278438.1, NM_001291509.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
ProteomicsDBi | 334656 |
Protocols and materials databases
Antibodypediai | 1079, 402 antibodies from 37 providers |
DNASUi | 18514 |
Genome annotation databases
Ensembli | ENSMUST00000064438; ENSMUSP00000066385; ENSMUSG00000052534 |
GeneIDi | 18514 |
UCSCi | uc007dlg.2, mouse |
Organism-specific databases
CTDi | 5087 |
MGIi | MGI:97495, Pbx1 |
VEuPathDBi | HostDB:ENSMUSG00000052534 |
Phylogenomic databases
GeneTreei | ENSGT00940000154374 |
OrthoDBi | 804740at2759 |
Miscellaneous databases
BioGRID-ORCSi | 18514, 0 hits in 63 CRISPR screens |
ChiTaRSi | Pbx1, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000052534, Expressed in rostral migratory stream and 311 other tissues |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR005542, PBX |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF03792, PBC, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS50071, HOMEOBOX_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D9J2V6_MOUSE | |
Accessioni | D9J2V6Primary (citable) accession number: D9J2V6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 5, 2010 |
Last sequence update: | October 5, 2010 | |
Last modified: | January 19, 2022 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |