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Protein
Submitted name:

Pre-B-cell leukemia transcription factor 1

Gene

Pbx1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi233 – 281HomeoboxPROSITE-ProRule annotationAdd BLAST49

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pre-B-cell leukemia transcription factor 1Imported
Submitted name:
Pre-B-cell leukemia transcription factor 1dImported
Gene namesi
Name:Pbx1Imported
Synonyms:PBX1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:97495 Pbx1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000052534 Expressed in 292 organ(s), highest expression level in rostral migratory stream

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini231 – 280HomeoboxInterPro annotationAdd BLAST50

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili165 – 185Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0774 Eukaryota
ENOG410XRVF LUCA
GeneTreeiENSGT00390000016426

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR005542 PBX
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF03792 PBC, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

D9J2V6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI
60 70 80 90 100
MTITDQSLDE AQARKHALNC HRMKPALFNV LCEIKEKTVL SIRGAQEEEP
110 120 130 140 150
TDPQLMRLDN MLLAEGVAGP EKGGGSAAAA AAAAASGGAG SDNSVEHSDY
160 170 180 190 200
RAKLSQIRQI YHTELEKYEQ ACNEFTTHVM NLLREQSRTR PISPKEIERM
210 220 230 240 250
VSIIHRKFSS IQMQLKQSTC EAVMILRSRF LDARRKRRNF NKQATEILNE
260 270 280 290 300
YFYSHLSNPY PSEEAKEELA KKCGITVSQV DTLRHVISQT GGYSDGLAAS
310 320 330
QMYSPQGISA NGGWQDATTP SSVTSPTEGP GSVHSDTSN
Length:339
Mass (Da):37,048
Last modified:October 5, 2010 - v1
Checksum:i14256F1FF11C5814
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P41778PBX1_MOUSE
Pre-B-cell leukemia transcription f...
Pbx1 Pbx-1
430Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093320 Genomic DNA No translation available.
AC096625 Genomic DNA No translation available.
AC112152 Genomic DNA No translation available.
AC116129 Genomic DNA No translation available.
HM369110 mRNA Translation: ADK11716.1
RefSeqiNP_001278438.1, NM_001291509.1
UniGeneiMm.43358
Mm.440114

Genome annotation databases

EnsembliENSMUST00000064438; ENSMUSP00000066385; ENSMUSG00000052534
GeneIDi18514
UCSCiuc007dlg.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093320 Genomic DNA No translation available.
AC096625 Genomic DNA No translation available.
AC112152 Genomic DNA No translation available.
AC116129 Genomic DNA No translation available.
HM369110 mRNA Translation: ADK11716.1
RefSeqiNP_001278438.1, NM_001291509.1
UniGeneiMm.43358
Mm.440114

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000064438; ENSMUSP00000066385; ENSMUSG00000052534
GeneIDi18514
UCSCiuc007dlg.2 mouse

Organism-specific databases

CTDi5087
MGIiMGI:97495 Pbx1

Phylogenomic databases

eggNOGiKOG0774 Eukaryota
ENOG410XRVF LUCA
GeneTreeiENSGT00390000016426

Miscellaneous databases

ChiTaRSiPbx1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000052534 Expressed in 292 organ(s), highest expression level in rostral migratory stream

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR005542 PBX
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF03792 PBC, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD9J2V6_MOUSE
AccessioniPrimary (citable) accession number: D9J2V6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: September 12, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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