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UniProtKB - D7GJ95 (D7GJ95_PROFC)

Entry version 62 (25 May 2022)
Sequence version 1 (10 Aug 2010)
Previous versions | rss
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Protein

Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Gene

bluB

Organism
Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: alpha-ribazole biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes alpha-ribazole from 5,6-dimethylbenzimidazole.ARBA annotation This subpathway is part of the pathway alpha-ribazole biosynthesis, which is itself part of Nucleoside biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes alpha-ribazole from 5,6-dimethylbenzimidazole, the pathway alpha-ribazole biosynthesis and in Nucleoside biosynthesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferaseImportedARBA annotation, OxidoreductaseImported, Transferase
Biological processCobalamin biosynthesisARBA annotation

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		1.13.11.79, 5032
2.4.2.21, 5031

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00061;UER00516

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseARBA annotation (EC:2.4.2.21ARBA annotation)
Alternative name(s):
N(1)-alpha-phosphoribosyltransferaseARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:bluBImported
Synonyms:cobT2Imported
Ordered Locus Names:PFREUD_06370Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPropionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri754252 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Actinobacteria › Propionibacteriales › Propionibacteriaceae › Propionibacterium ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000936 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		754252.PFREUD_06370

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini61 – 227NitroreductaseInterPro annotationAdd BLAST167

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 45DisorderedSequence analysisAdd BLAST45

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CobT family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG0778, Bacteria
COG2038, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002982_2_2_11

Identification of Orthologs from Complete Genome Data

More...OMAi		WLCLGWP

Database of Orthologous Groups

More...OrthoDBi		1765140at2

Family and domain databases

Conserved Domains Database

More...CDDi		cd02439, DMB-PRT_CobT, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1610.10, 1 hit
3.40.109.10, 1 hit
3.40.50.10210, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012825, BluB
IPR003200, Nict_dMeBzImd_PRibTrfase
IPR023195, Nict_dMeBzImd_PRibTrfase_N
IPR036087, Nict_dMeBzImd_PRibTrfase_sf
IPR029479, Nitroreductase
IPR000415, Nitroreductase-like

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02277, DBI_PRT, 1 hit
PF00881, Nitroreductase, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52733, SSF52733, 1 hit
SSF55469, SSF55469, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR02476, BluB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D7GJ95-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDEARDPET TNPADEPLPG DHLFERPVPN VGDDSSVNER DRDVSGWAFD 
        60         70         80         90        100
QATQAALDRV IGARRDIRRF RPDPVSDELV REVLNAGHGG PSVGQSQPWR 
       110        120        130        140        150
FIIVKDRRTR ERAALMSDRE RMRQSRQLTA ERSQRLLDLQ LEGIREAPLG 
       160        170        180        190        200
IVVACDRRAP AAGVLGRNTF HDADMWSCAA AIENMWLTAR ALGLGMGWVT 
       210        220        230        240        250
LMQPDELAGL LNLPEGVTTL GWLCLGWPNE RPPYPGLERR AWSHKLPLDQ 
       260        270        280        290        300
VVMTDRWPDN GPEPPVSALA GMAPAEPVES LITRPIPDDP SSVLWSDVHA 
       310        320        330        340        350
PSPQQVVDAR DKGEKLLTPP GSLGKLDQAL DRLVAASGDQ VTGGTLVLVG 
       360        370        380        390        400
ADHPLNAHKV SAFDQSVSRQ VMEAALEGRA VGVVTARSAG LDVMVVDAGI 
       410        420        430        440        450
DGGPVAGCEL ARPEDVRGDL VNTPAMTTAD VRRLVTRGRE LGARAAERGV 
       460        470        480        490        500
VCLGEIGIGN TTIASALACV FTGITPEQAA GIGAGSDAKM VEHKAEVLRA 
       510        520        530        540        550
IFARTDITAL RADPALALAE VGGPEFAVLA GVILGAVEAG STVVLDGLAG 
       560        570        580        590        600
SVPALAVVEV NPAVQSYLIA GQVSREFAHG AVLTRLGLEP LVSLRLRAGE 
       610        620 
GVGASLATQM LFSGLAVRRQ SGRTEE
Length:626
Mass (Da):66,408
Last modified:August 10, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i16D63A5F07DD71EA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
FN806773 Genomic DNA Translation: CBL56167.1

NCBI Reference Sequences

More...RefSeqi		WP_013160556.1, NC_014215.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		CBL56167; CBL56167; PFREUD_06370

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		pfr:PFREUD_06370

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN806773 Genomic DNA Translation: CBL56167.1
RefSeqiWP_013160556.1, NC_014215.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi754252.PFREUD_06370

Genome annotation databases

EnsemblBacteriaiCBL56167; CBL56167; PFREUD_06370
KEGGipfr:PFREUD_06370

Phylogenomic databases

eggNOGiCOG0778, Bacteria
COG2038, Bacteria
HOGENOMiCLU_002982_2_2_11
OMAiWLCLGWP
OrthoDBi1765140at2

Enzyme and pathway databases

UniPathwayiUPA00061;UER00516
BRENDAi1.13.11.79, 5032
2.4.2.21, 5031

Family and domain databases

CDDicd02439, DMB-PRT_CobT, 1 hit
Gene3Di1.10.1610.10, 1 hit
3.40.109.10, 1 hit
3.40.50.10210, 1 hit
InterProiView protein in InterPro
IPR012825, BluB
IPR003200, Nict_dMeBzImd_PRibTrfase
IPR023195, Nict_dMeBzImd_PRibTrfase_N
IPR036087, Nict_dMeBzImd_PRibTrfase_sf
IPR029479, Nitroreductase
IPR000415, Nitroreductase-like
PfamiView protein in Pfam
PF02277, DBI_PRT, 1 hit
PF00881, Nitroreductase, 1 hit
SUPFAMiSSF52733, SSF52733, 1 hit
SSF55469, SSF55469, 1 hit
TIGRFAMsiTIGR02476, BluB, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD7GJ95_PROFC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D7GJ95
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 25, 2022
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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