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Entry version 33 (16 Oct 2019)
Sequence version 1 (10 Aug 2010)
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Protein
Submitted name:

Uncharacterized protein

Gene

Esi_0300_0013

Organism
Ectocarpus siliculosus (Brown alga) (Conferva siliculosa)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:Esi_0300_0013Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEctocarpus siliculosus (Brown alga) (Conferva siliculosa)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri2880 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaStramenopilesPX cladePhaeophyceaeEctocarpalesEctocarpaceaeEctocarpus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002630 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome LG05

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini60 – 367AAA_34InterPro annotationAdd BLAST308
Domaini577 – 892Helicase_C_4InterPro annotationAdd BLAST316

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni941 – 967DisorderedSequence analysisAdd BLAST27
Regioni1124 – 1143DisorderedSequence analysisAdd BLAST20
Regioni1156 – 1252DisorderedSequence analysisAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili8 – 29Sequence analysisAdd BLAST22
Coiled coili528 – 548Sequence analysisAdd BLAST21
Coiled coili555 – 575Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1204 – 1220PolarSequence analysisAdd BLAST17

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000043949

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D7FWB6

Identification of Orthologs from Complete Genome Data

More...
OMAi
IEASHIP

Database of Orthologous Groups

More...
OrthoDBi
141580at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase
IPR026937 SBNO_Helicase_C_dom
IPR026741 SNO
IPR039187 SNO_AAA

The PANTHER Classification System

More...
PANTHERi
PTHR12706 PTHR12706, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13872 AAA_34, 1 hit
PF13871 Helicase_C_4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D7FWB6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEVPAVDVAS ALREAAALEE KKLKDKQQAE ADNALAEEVD VEVFSAYECR
60 70 80 90 100
SLPPELGNAH PGDISEPGLL SAVPLPPPTY GSEAFDGPVI DETKLSRLQL
110 120 130 140 150
EGVLFAAQRH THLLPDGKRA GFFIGDGAGV GKGRQIAGII LDSWARGRKK
160 170 180 190 200
HVWFSISNDL KLDAQRDLKD VGCHINVIDG CQGLDAASSK GLGMSSSSKH
210 220 230 240 250
GCLFSTYSTL ASGRPNAVGK KTRLEQLIDW CGGKDFEGCL VFDEAHKAKN
260 270 280 290 300
FNSSKEELST KVSQAVIKIQ DMLPKARVVY CSATGVTDIG NLAYATRLGL
310 320 330 340 350
WGEHSPFRGF KEFKESMEKR GLGALEMLAM ELKAKGSYVS RGLGWKGAEF
360 370 380 390 400
ETCEVKLPPS TVEMYDKAVE FWMLLRKELE KAASACGNSG MCKAERCKDD
410 420 430 440 450
HVCSPMRQFW GQQQRFFKEM ANASKVEFVV AQAKEALSSG MSVVIGLQST
460 470 480 490 500
GESGMDKAMS EMKKRPGDTV ATLISAAHYG TIGFIKQFFP TRTVPKEVKV
510 520 530 540 550
MTDQDIEDII SCQLNVHIQA GIATLFNVEQ ARASLRKDQE RSKVLKAEQA
560 570 580 590 600
KSRELQDCVE AKEKLLQKAK ELRLLPSPLD ALIDALGGTA EVAEMTGRRG
610 620 630 640 650
RLVRRVRGDA GFKYDLRPEN EETSLNIRER ELFMSGKKKV AIISDAASTG
660 670 680 690 700
VSLHAAVGSG SEGRRRLHIT LELPWSADKA IQQLGRSHRS NQASAPVFRL
710 720 730 740 750
LVTDLGGERR FAAAVAKRLA SLGALTKGDR RAATGADFSS FDLDTKYGRR
760 770 780 790 800
ALKSMMMAIV TKTGLAPGVD LMTLRPFVQS GLLMSTAPAA ATPTPSSVNQ
810 820 830 840 850
GGATGAAGMM AEELGQEAKA EIKIAAMLAA ERSLEDMAIE PAQYNNVTLF
860 870 880 890 900
LGRLQGLPVQ RQNLMFTYLT GTLDAVLSEA RASGVYDEGV ADLRASSVTL
910 920 930 940 950
KNAPEEVAKD PATGAVTQLA QVVLDRGVSW DQALAKRSEA ADAGMDEAVK
960 970 980 990 1000
PTSGAKPPKG TGFYRSRHTD ITSQRKLVVL AVRKAKHNRL MVITRPNTGT
1010 1020 1030 1040 1050
SGYEMDLQEL REKYDRVSDN EEATATVQHA WTQAYDSSNG ADYRGSRKVT
1060 1070 1080 1090 1100
LGLLSGSVLP MWSALEKTVA VCRAQMTKAE EALKVNRVIL DDSTKLVGVR
1110 1120 1130 1140 1150
LPTTALSTLR QHLAEAVQAR KAVVDSGGGG GVDPVSPINP KTLLQVKTPP
1160 1170 1180 1190 1200
KNILSFFGRA ASPSPSSAAT PPPVGGKRHA GVSSVGGSAG RVKKKKGSVG
1210 1220 1230 1240 1250
GSGRNAGKEN SASSTAKGVA ALFGSQLGSK DTAGSTASAK RDDPPEVISI

DD
Length:1,252
Mass (Da):134,182
Last modified:August 10, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBFE035BD689C5404
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FN648488 Genomic DNA Translation: CBJ32004.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CBJ32004; CBJ32004; Esi_0300_0013

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN648488 Genomic DNA Translation: CBJ32004.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblProtistsiCBJ32004; CBJ32004; Esi_0300_0013

Phylogenomic databases

HOGENOMiHOG000043949
InParanoidiD7FWB6
OMAiIEASHIP
OrthoDBi141580at2759

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR026937 SBNO_Helicase_C_dom
IPR026741 SNO
IPR039187 SNO_AAA
PANTHERiPTHR12706 PTHR12706, 1 hit
PfamiView protein in Pfam
PF13872 AAA_34, 1 hit
PF13871 Helicase_C_4, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD7FWB6_ECTSI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D7FWB6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: October 16, 2019
This is version 33 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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