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Protein

Alanine racemase

Gene

Bsel_0530

Organism
Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (Bsel_0530)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei57Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei155SubstrateUniRule annotation1
Active sitei288Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei335Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Bsel_0530Imported
OrganismiBacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10)Imported
Taxonomic identifieri439292 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesSporolactobacillaceaeunclassified Sporolactobacillaceae
Proteomesi
  • UP000000271 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei57N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi439292.Bsel_0530

Structurei

3D structure databases

ProteinModelPortaliD6XXZ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini267 – 392Ala_racemase_CInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CJ4 Bacteria
COG0787 LUCA
HOGENOMiHOG000031444
KOiK01775
OMAiWEILCGF
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.10, 2 hits
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

D6XXZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQIQEIYRK AGDQAVDVTH PFYRDTWAEI DLNAIHDNVT AIKASLPAHT
60 70 80 90 100
EMMAVVKANA YGHGAVDVAR EALDAGATYL GVAILDEAIA LRKAGIGAPI
110 120 130 140 150
LVLGYIRAED ILIASELDIA VTVFQKDWLE KAESLLRAAG RKAVCHVKLD
160 170 180 190 200
SGMGRIGLRK EEEIRELAEV LKASLHIHVE GAYTHMAAAD EPGNDYYHVQ
210 220 230 240 250
KERFLDMMDW LESSLGEKVK IRHCANSASA LRFHEESCNL VRVGISMYGM
260 270 280 290 300
APSVEMKPDM KVPLKQAMSL KSRITQVKLL EPGEGISYGS TYRTSGHEWI
310 320 330 340 350
GTVPIGYADG WIRAHQSGDV LVKGKRAKIV GRICMDQMMI LLDGPVETGT
360 370 380 390 400
EVTLIGEDGG SFLSMDEVAG RIDTISYEIP CTLSYRVPRA VRKDGRVLYV

HNDIF
Length:405
Mass (Da):44,650
Last modified:August 10, 2010 - v1
Checksum:iBE8DCBFAA4D25060
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001791 Genomic DNA Translation: ADH98066.1

Genome annotation databases

EnsemblBacteriaiADH98066; ADH98066; Bsel_0530
KEGGibse:Bsel_0530

Similar proteinsi

Entry informationi

Entry nameiD6XXZ3_BACIE
AccessioniPrimary (citable) accession number: D6XXZ3
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: July 18, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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