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Entry version 57 (12 Aug 2020)
Sequence version 1 (10 Aug 2010)
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Protein
Submitted name:

Cell division cycle 5-like protein

Gene

TcasGA2_TC011382

Organism
Tribolium castaneum (Red flour beetle)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell divisionImported, mRNA processing, mRNA splicing

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cell division cycle 5-like proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TcasGA2_TC011382Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTribolium castaneum (Red flour beetle)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7070 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaColeopteraPolyphagaCucujiformiaTenebrionidaeTenebrionidae incertae sedisTribolium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007266 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Keywords - Cellular componenti

    SpliceosomeARBA annotation

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    7070.TC011382-PA

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 58HTH myb-typeInterPro annotationAdd BLAST58
    Domaini59 – 108HTH myb-typeInterPro annotationAdd BLAST50

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni109 – 145DisorderedSequence analysisAdd BLAST37
    Regioni190 – 210DisorderedSequence analysisAdd BLAST21
    Regioni236 – 291DisorderedSequence analysisAdd BLAST56

    Coiled coil

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili168 – 189Sequence analysisAdd BLAST22
    Coiled coili656 – 686Sequence analysisAdd BLAST31
    Coiled coili705 – 725Sequence analysisAdd BLAST21
    Coiled coili758 – 798Sequence analysisAdd BLAST41

    Compositional bias

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi236 – 273PolyampholyteSequence analysisAdd BLAST38

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the CEF1 family.ARBA annotation

    Keywords - Domaini

    Coiled coilSequence analysis

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0050, Eukaryota

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_009082_0_0_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    D6X4C5

    KEGG Orthology (KO)

    More...
    KOi
    K12860

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    PFRTQRE

    Database of Orthologous Groups

    More...
    OrthoDBi
    975557at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    D6X4C5

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd00167, SANT, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR021786, Cdc5p/Cef1
    IPR009057, Homeobox-like_sf
    IPR017930, Myb_dom
    IPR001005, SANT/Myb

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF11831, Myb_Cef, 1 hit

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM00717, SANT, 2 hits

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF46689, SSF46689, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS51294, HTH_MYB, 2 hits

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    D6X4C5-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MPRIMIKGGV WRNTEDEILK AAVMKYGKNQ WSRIASLLHR KSAKQCKARW
    60 70 80 90 100
    FEWLDPSIKK TEWSREEDEK LLHLAKLMPT QWRTIAPIIG RTAAQCLERY
    110 120 130 140 150
    EYLLDQAQKK EEGEDVTDDP RKLKPGEIDP NPETKPARPD PKDMDEDELE
    160 170 180 190 200
    MLSEARARLA NTQGKKAKRK AREKQLEEAR RLAALQKRRE LRAAGIEVNS
    210 220 230 240 250
    RRKKKRGVDY NEEIPFEKRP AIGFYDTSTE IVDPMAPDFH KMRQQHLDGE
    260 270 280 290 300
    LRSEQEERER RKDKQKLKQR KENDIPQAML QNQEPAKKRS KLVLPEPQIS
    310 320 330 340 350
    DLELQQVVKL GKASEVAREV AAESGIESTD TLFNDYTVAA PQAAAVTPRT
    360 370 380 390 400
    PAPQTDRILQ EAQNVMALTH VDTPLKGGRN TPLHNSDFSG VLPQALTIAT
    410 420 430 440 450
    PNTVLATPFG AQTPGFMTPQ GPQGSFTPSV RDKLNINEEN TEMVAQTPAE
    460 470 480 490 500
    QRSLQNNLKE QLRLGLSSLP TPKNDYEIVV PEQEEEEKEE EKTPNIVEDQ
    510 520 530 540 550
    ADVDARALEE AKIRAAQELA LRSQVIQRGL PRPHDVNLAV LRPNHESHSL
    560 570 580 590 600
    TELQKAEELI KCEMVTMLQF DNLKNPNQVK RSALAQAQQL AFLEQHPYDD
    610 620 630 640 650
    FKSDDLKLAK QLLKREMEIV KYGMGHGELP LEAYTQVWEE CLGQVLFVPN
    660 670 680 690 700
    LNKYTRANLV SKKERLESAE KRLEQNRSHM AREAKKAAKM EKKLKILTGG
    710 720 730 740 750
    YQSRAQALIK QLADYYDQID QANLELNTFK FLQEQEKAAL PRRIQSLTED
    760 770 780 790
    VNRQMEREKG LQGRYGELQG QIKELQSELE KLQQEIEVAR GEQEGEAE
    Length:798
    Mass (Da):91,347
    Last modified:August 10, 2010 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8816F532E67665B3
    GO

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    KQ971410 Genomic DNA Translation: EEZ97534.1

    NCBI Reference Sequences

    More...
    RefSeqi
    XP_969684.1, XM_964591.3

    Genome annotation databases

    Ensembl metazoan genome annotation project

    More...
    EnsemblMetazoai
    TC011382_001; TC011382_001; TC011382

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    658182

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    tca:658182

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    KQ971410 Genomic DNA Translation: EEZ97534.1
    RefSeqiXP_969684.1, XM_964591.3

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    STRINGi7070.TC011382-PA

    Genome annotation databases

    EnsemblMetazoaiTC011382_001; TC011382_001; TC011382
    GeneIDi658182
    KEGGitca:658182

    Phylogenomic databases

    eggNOGiKOG0050, Eukaryota
    HOGENOMiCLU_009082_0_0_1
    InParanoidiD6X4C5
    KOiK12860
    OMAiPFRTQRE
    OrthoDBi975557at2759
    PhylomeDBiD6X4C5

    Family and domain databases

    CDDicd00167, SANT, 1 hit
    InterProiView protein in InterPro
    IPR021786, Cdc5p/Cef1
    IPR009057, Homeobox-like_sf
    IPR017930, Myb_dom
    IPR001005, SANT/Myb
    PfamiView protein in Pfam
    PF11831, Myb_Cef, 1 hit
    SMARTiView protein in SMART
    SM00717, SANT, 2 hits
    SUPFAMiSSF46689, SSF46689, 1 hit
    PROSITEiView protein in PROSITE
    PS51294, HTH_MYB, 2 hits

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD6X4C5_TRICA
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D6X4C5
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: August 12, 2020
    This is version 57 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteomeImported
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