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UniProtKB - D6WSQ2 (D6WSQ2_TRICA)

Entry version 45 (02 Dec 2020)
Sequence version 1 (10 Aug 2010)
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Protein
Submitted name:

Digestive organ expansion factor homolog-like Protein

Gene

TcasGA2_TC008696

Organism
Tribolium castaneum (Red flour beetle)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Digestive organ expansion factor homolog-like ProteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TcasGA2_TC008696Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTribolium castaneum (Red flour beetle)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7070 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Coleoptera › Polyphaga › Cucujiformia › Tenebrionidae › Tenebrionidae incertae sedis › Tribolium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007266 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Linkage group 7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		7070.TC008696-PA

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 162DisorderedSequence analysisAdd BLAST162

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 17PolyampholyteSequence analysisAdd BLAST17
Compositional biasi32 – 69PolyampholyteSequence analysisAdd BLAST38
Compositional biasi90 – 104PolarSequence analysisAdd BLAST15
Compositional biasi105 – 152AcidicSequence analysisAdd BLAST48

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2340, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_018705_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		D6WSQ2

Identification of Orthologs from Complete Genome Data

More...OMAi		HALNHVF

Database of Orthologous Groups

More...OrthoDBi		257318at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		D6WSQ2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR010678, Digest_organ_expansion_fac-prd

The PANTHER Classification System

More...PANTHERi		PTHR12933, PTHR12933, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF06862, UTP25, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D6WSQ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARGKVKYRD VVGGRSKKSK KFDKKKTKPR KTYSLYRQDT KKPTKKRKFE 
        60         70         80         90        100
ASEENYEKRQ KVEKEAQPEQ ESSESEEEID PMKELMSTFG SKLQHKQSLA 
       110        120        130        140        150
ISSSDESSDE EDENSPEDIL EENEDTDEET LTKNEDTPDS EEDEDEVAVD 
       160        170        180        190        200
SAQNEDSDNL NDPFVKHVCY ELHESVLKSL QSSPVLVNDS VLNWPSLGRL 
       210        220        230        240        250
LVQIPQFEEL KEEKNSFTIE EKKKFAPPGS VPKKMNTSDL KKPENLFIKS 
       260        270        280        290        300
QIIDNLSKAN DSLKKDDTVF TDFQSELFSI INNYQDLYFT QRNFNNAEEI 
       310        320        330        340        350
RFVYCLHAVN HILKTRLKVV HHNVRLSKKD DVPEDFRDQG LVRPKILMVV 
       360        370        380        390        400
PFKDSAFKII QMIINILLPE DKGHVMNKKR FLEEYTGNEI PMPKKNPKPE 
       410        420        430        440        450
DYELTFTGNT SDDFKIGITV TKKSLKLFAD FYSSDIIIAS PLGLRTIIGA 
       460        470        480        490        500
EGEPQRDYDF LASIELLILD QTELFSMQNW DHFIHVINHL HLQPKDSHGT 
       510        520        530        540        550
DFSRVRTWSL NGWAQYYRQT LIFSSIVLPE INSIFNKKCN NFAGKVKISN 
       560        570        580        590        600
PVELGSIGQV VVQIPHVFHK FEAPNAQAAI EARFEFFINK LLPLQRDSLM 
       610        620        630        640        650
KQTMIYVPSY FDFVRLRNYF KKEELSFGQI CEYSKDGKVA RARDMFYHGD 
       660        670        680        690        700
THSLLYTERF HFFNRVRVKG IRHLVFYQPP TFPHFYYEMC NLMQEANMNK 
       710        720        730        740 
KIGSLSNMTV NVIYSKYDVH RLAAIVGTER ATKMLQSERN VHMMVTGAD
Length:749
Mass (Da):86,976
Last modified:August 10, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4F6B82160B30BCDC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
KQ971354 Genomic DNA Translation: EFA05884.1

NCBI Reference Sequences

More...RefSeqi		XP_008196323.1, XM_008198101.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		TC008696_001; TC008696_001; TC008696

Database of genes from NCBI RefSeq genomes

More...GeneIDi		660244

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		tca:660244

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ971354 Genomic DNA Translation: EFA05884.1
RefSeqiXP_008196323.1, XM_008198101.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi7070.TC008696-PA

Genome annotation databases

EnsemblMetazoaiTC008696_001; TC008696_001; TC008696
GeneIDi660244
KEGGitca:660244

Phylogenomic databases

eggNOGiKOG2340, Eukaryota
HOGENOMiCLU_018705_1_0_1
InParanoidiD6WSQ2
OMAiHALNHVF
OrthoDBi257318at2759
PhylomeDBiD6WSQ2

Family and domain databases

InterProiView protein in InterPro
IPR010678, Digest_organ_expansion_fac-prd
PANTHERiPTHR12933, PTHR12933, 1 hit
PfamiView protein in Pfam
PF06862, UTP25, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD6WSQ2_TRICA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D6WSQ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: December 2, 2020
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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