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Protein
Submitted name:

Ryanodine receptor 44F-like Protein

Gene

TcasGA2_TC002610

Organism
Tribolium castaneum (Red flour beetle)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi4106 – 4117PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported
LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ryanodine receptor 44F-like ProteinImported
Gene namesi
ORF Names:TcasGA2_TC002610Imported
OrganismiTribolium castaneum (Red flour beetle)Imported
Taxonomic identifieri7070 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaColeopteraPolyphagaCucujiformiaTenebrionidaeTenebrionidae incertae sedisTribolium
Proteomesi
  • UP000007266 Componenti: Linkage group 3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4346 – 4373HelicalSequence analysisAdd BLAST28
Transmembranei4545 – 4563HelicalSequence analysisAdd BLAST19
Transmembranei4618 – 4640HelicalSequence analysisAdd BLAST23
Transmembranei4764 – 4785HelicalSequence analysisAdd BLAST22
Transmembranei4808 – 4830HelicalSequence analysisAdd BLAST23
Transmembranei4888 – 4907HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini99 – 153MIRInterPro annotationAdd BLAST55
Domaini160 – 205MIRInterPro annotationAdd BLAST46
Domaini273 – 331MIRInterPro annotationAdd BLAST59
Domaini339 – 397MIRInterPro annotationAdd BLAST59
Domaini576 – 801B30.2/SPRYInterPro annotationAdd BLAST226
Domaini1030 – 1213B30.2/SPRYInterPro annotationAdd BLAST184
Domaini1466 – 1688B30.2/SPRYInterPro annotationAdd BLAST223
Domaini4102 – 4128EF-handInterPro annotationAdd BLAST27

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili463 – 483Sequence analysisAdd BLAST21
Coiled coili3699 – 3719Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2243 Eukaryota
ENOG410YCNW LUCA
InParanoidiD6WF72

Family and domain databases

CDDicd12877 SPRY1_RyR, 1 hit
cd12878 SPRY2_RyR, 1 hit
cd12879 SPRY3_RyR, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR013320 ConA-like_dom_sf
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR014821 Ins145_P3_rcpt
IPR005821 Ion_trans_dom
IPR036300 MIR_dom_sf
IPR016093 MIR_motif
IPR013662 RIH_assoc-dom
IPR000699 RIH_dom
IPR013333 Ryan_recept
IPR003032 Ryanodine_rcpt
IPR015925 Ryanodine_recept-rel
IPR009460 Ryanrecept_TM4-6
IPR035910 RyR/IP3R_RIH_dom_sf
IPR035761 SPRY1_RyR
IPR035764 SPRY2_RyR
IPR035762 SPRY3_RyR
IPR003877 SPRY_dom
PANTHERiPTHR13715 PTHR13715, 3 hits
PfamiView protein in Pfam
PF08709 Ins145_P3_rec, 1 hit
PF00520 Ion_trans, 1 hit
PF02815 MIR, 1 hit
PF08454 RIH_assoc, 1 hit
PF06459 RR_TM4-6, 1 hit
PF01365 RYDR_ITPR, 2 hits
PF02026 RyR, 4 hits
PF00622 SPRY, 3 hits
PRINTSiPR00795 RYANODINER
SMARTiView protein in SMART
SM00472 MIR, 4 hits
SM00449 SPRY, 3 hits
SUPFAMiSSF100909 SSF100909, 1 hit
SSF47473 SSF47473, 1 hit
SSF49899 SSF49899, 3 hits
SSF82109 SSF82109, 2 hits
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 3 hits
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit
PS50919 MIR, 4 hits

Sequencei

Sequence statusi: Complete.

D6WF72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEAEGGSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCFLENI
60 70 80 90 100
ADKNIPPDLS QCVFVIEQAL SVRALQELVT AAGNETGQEN LGKGTGSGHR
110 120 130 140 150
TLLYGNAILL RHQNSDMYLA CLSTSSSNDK LAFDVGLQEH SQGEACWWTV
160 170 180 190 200
HPASKQRSEG EKVRVGDDLI LVSVATERYL HTTKENEISI VNASFHVTHW
210 220 230 240 250
SVQPYGTGIS RMKYVGYVFG GDVLRFFHGG DECLTIPSTW SIDANIVIYE
260 270 280 290 300
GGSVMSQARS LWRLELARTK WAGGFINWSH PMRIRHITTG RYLAVNENNE
310 320 330 340 350
LYLVSREEAN TATTAFCLRQ EKDDQKVVLE DKDLEVIGSP IIKYGDSTVI
360 370 380 390 400
VQHSETGLWL SYKSYETKKK GVGKVEEKQA ILHEEGKMDD GLDFSRSQEE
410 420 430 440 450
ESRTARVIRK CSSLFTQFIN GLETLQMNRR HSVFFLAVNL NEMVMCLEDL
460 470 480 490 500
INYFAQPEDD MEHEEKQNRF RALRNRQDLF QEEGILNLIL EAIDKINVIT
510 520 530 540 550
SQGFLAGLAG DQNWEMISGY LYQLLAAIIK GNHTNCAQFA NSNRLNWLFS
560 570 580 590 600
RLGSQASSEG TGMLDVLHCV LIDSPEALNM MRDEHIKVII SLLEKHGRDP
610 620 630 640 650
KVLDVLCSLC VGNGVAVRSS QNNICDYLLP GKNLLLQTQL VDHVASVRPN
660 670 680 690 700
IFVGRVDGSA IYQKWYFEVT VDHIEQTTHM MPHLRIGWAN SKGYVPYPGG
710 720 730 740 750
GEKWGGNGVG DDLYSYGFDG VYLWSGGRST QVVTTYTTPF IKKNDVVGCA
760 770 780 790 800
LDLTVPIITF TFNGVPIKGS FRNFNLDGMF FPVISCSSKL SCRFLLGGDH
810 820 830 840 850
GRLKYIPPEE FSPLVESLLP QQILNLEPCF YFGNMNKNVI AGPLTVEDDT
860 870 880 890 900
AFVPNPVDTS MVSLASYVES IRDKLAENIH EMWAMNKIEA GWQWGEYRDD
910 920 930 940 950
LRHIHPCLVP FDKLPPAEKK YDSQLAVQTL KTIIALGYHI TMDKPPSRIK
960 970 980 990 1000
TVRLPNEPFM QSNGYKPAPL DLSAITLTPK LEELVDQLAE NTHNLWAKER
1010 1020 1030 1040 1050
IQQGWTYGLN EDPDMFRSPH LVPYIKVDDA IKKANRDTAS ETVRTLLVYG
1060 1070 1080 1090 1100
YNLDPPTGEQ HEALLAEASR SRQAIFRTYR AEKNYAVSSG KWYFEFEILT
1110 1120 1130 1140 1150
AGPMRVGWAK ADCAPGCMLG SDENTWAFDG YNEEKVYSNS AESFGKQWQV
1160 1170 1180 1190 1200
GDVVGVFLDL IDHTISFSLN GELLMDALGG ETTFADVQGD NFVPAFTLGV
1210 1220 1230 1240 1250
GQKARLCFGQ DVTQLKYFTM CGLQEGYEPF CVNMKRPVTY WYTKDQPIFE
1260 1270 1280 1290 1300
NTDDMPDTKI DVTRILAGSD SPPCLKISHN TFETMEKANW EFLRLSLPVI
1310 1320 1330 1340 1350
CHSTFISEDE KMRRWQEIKI RQHRLKAEAE SNISPAHIEQ MMMKSGFSMS
1360 1370 1380 1390 1400
DIKGLHRNYS EDAVESDEVM KHHGKSTKSM PARPPRKGSL SRNVNGFEDN
1410 1420 1430 1440 1450
MLGANTGRGV NRSTSELNLN RYHDMAPANQ EKPDEKKKRG RSPFRFFSRK
1460 1470 1480 1490 1500
KAGNSPGGES VKADKSKTPD RERERMGTIK VPTRQAGVSP SRLTRSPTIK
1510 1520 1530 1540 1550
QSQSDLMQVP AAASGQQKQL SVPHTSDVEA VGDELFDGEC LKLINEYFYG
1560 1570 1580 1590 1600
VRIFPGQDPT HVYVGWVTTQ YHRHTKDFNQ NQVRKSSIVI LDDYDRVVDC
1610 1620 1630 1640 1650
VDRQSCYMVR ADELYNQVTQ DASGKGASQG MFIGCFLDAA TGVITFTCEG
1660 1670 1680 1690 1700
KPTSHVFRME PETKLFPAIF VEATSKEILQ IELGRTPTSL PLSAAVLQNS
1710 1720 1730 1740 1750
AKHVIPQFPP RLKVQCLKPH QWARVPNQSL QVHALKLSDI RGWSMLCEDA
1760 1770 1780 1790 1800
ISMLALHIPE EDRCIDVLEL IEMDKLLSFH AHTLTLYAAL CYQSNYKAAH
1810 1820 1830 1840 1850
VLCKHVNQRQ LLYAIKAEYM SGPLRQGFYD LLIAVHIESA ATTMEVCQNE
1860 1870 1880 1890 1900
YVIPLSQELK EMYEDPEMRH SLRALMMESV QPQMKMSDIT DTVENIKNLY
1910 1920 1930 1940 1950
SPYFPLDIVR DYVMTALAEA VETNQVHNRD PIGGSNENLF LPLLKLVDRL
1960 1970 1980 1990 2000
LLVGMLRDED IAKLLIMICP ETWDPSFVKD GKDEHRKGLL SMKMAEGAKL
2010 2020 2030 2040 2050
QMCYLLQHLC DIQLRHRVES IIAFSHDFVG DLQSDQLRRY IEIKQSDLPS
2060 2070 2080 2090 2100
AVAAKKTREF RCPPREQMNA ILSFKNLEEE DKENCPLGEE LCEKLNDFHG
2110 2120 2130 2140 2150
LLMSHVSLQA LQAPEEEEGN DVQKPGPFKR LYNFINAVKE LEEEPKEEPE
2160 2170 2180 2190 2200
PEKKTPEEIF RKVLISTIVQ WAEEAQIETP KLVQEMFSLL VRQYDSVGEL
2210 2220 2230 2240 2250
IRALQKTYVI NAKTKQDVAE MWVGLSKIRA LLPVQMSQEE EELMRERLWK
2260 2270 2280 2290 2300
LVNNHTFFQH PDLIRVLRIH ENVMAVMINT LGRRSQAQSD AQAQAQAAEG
2310 2320 2330 2340 2350
DTTVKEKDTS HEMVVACCRF LCYFCRTGRQ NQKAMFEHFD FLLENSNILL
2360 2370 2380 2390 2400
ARPSLRGSTP LDVAYSSLME NTELALALRE HYLEKIAIYL SRCGLQSNSE
2410 2420 2430 2440 2450
LVEKGYPDLG WDPVEGERYL DFLRFCVWVN GESVEENANL VIRLLIRRPE
2460 2470 2480 2490 2500
CLGPALRGEG EGLLRAIVDA NKMSERISDR RKMMDEAEGT VNVAPFTHPL
2510 2520 2530 2540 2550
PESDDDEDYI DTGAAILNFY CTLVDLLGRC APDATVIELG KNESLRARAI
2560 2570 2580 2590 2600
LRSLVPLEDL QGVLSLRFTL QNPAAGEERP KSDMPSELRN ETQELSQIVG
2610 2620 2630 2640 2650
GSVSADLRCA TMLDRNDGSE SDMALSMNRY IGNSILPLLI QHSKFYSEAE
2660 2670 2680 2690 2700
NYASLLDATL HTVYRLSKNR MLTKGQREAV SDFLVALTSA LQPSMLLKLL
2710 2720 2730 2740 2750
RKLTVDVSNL SEYTTVALRL LTLHYDRCAK YYGSSTGQGL YGAASDEEKR
2760 2770 2780 2790 2800
LTMMLFSNIF DSLSKMDYDP ELFGKALPCL SAIGCALPPD YSLSKNYDDE
2810 2820 2830 2840 2850
WYANKSAKTG PDGPYNPQPI NTSSVALNND LNSIVQQFSE HYHDAWASRK
2860 2870 2880 2890 2900
LENGWQYGET WSDSNKTHPR LKPYSMLNDY EKERYKEPVR ESLKALLAIG
2910 2920 2930 2940 2950
WSVEHSEVDH PSTNRNSVHH QSGEGSSPFN YNPHPVDMTN LTLSREMQNM
2960 2970 2980 2990 3000
AERLAENAHD IWAKKKKEEL NTCGGGIHPQ LVPYDLLTDK EKRKDRERSQ
3010 3020 3030 3040 3050
EFLKYLQYQG YKLHKPIRGG QGETEQTTAG ASIELRFAYS LLEKLIQYAD
3060 3070 3080 3090 3100
RATINMKLLK PSSTFSRRPS YKTSSRDIKF FSKVVLPLME KYFSTHRNYF
3110 3120 3130 3140 3150
IAIATATNNV GAASLKEKEM VASLFCKLAS LLRSKLTAFG ADVRITVRCL
3160 3170 3180 3190 3200
QVLVKGIDAK SLVKNCPEFI RTSMLTFFNN TADDLGHTII NLQEGKYSHL
3210 3220 3230 3240 3250
RGTHLKTSTS LFYVNTVIIP ILTAMFDHLA NCEYGSDLLL DEIQVASYKI
3260 3270 3280 3290 3300
LQALYTLGTD TTLTHDRKYL KTEIEKYKPA LGSCLGAFSS TFPVAFLEPH
3310 3320 3330 3340 3350
LNKNNQFSLL NRIADHSLEA QAEHMNHLLK NVLKLIKKNI GNETAPWMTR
3360 3370 3380 3390 3400
IAAYTQQIII NSSEELLRDP FLPLAERVKK RTETMFHKEE SLRGFIKSSS
3410 3420 3430 3440 3450
DDTSQIETQI QEDWHLLVRD IYAFYPLLIK YVDLQRNHWL RHNIAEAEDL
3460 3470 3480 3490 3500
YNHVADIFNI WSKSQYFLRE EQNFISANEI DNMVLIMPTA TRRPVVTDGT
3510 3520 3530 3540 3550
QQTGGKKKKK HRDKKRDKDK EIQASLMVAC LKRLLPVGLN LFAGREQELV
3560 3570 3580 3590 3600
QHCKDRFLKK APEYDIIEFA KTQLTLPDKI DPADEMSWQH YLYSQLGSKK
3610 3620 3630 3640 3650
SAAVGMVDNN GKNLLEETVD RIVAMSKVLY GLHMIDHPQQ QQKGVYHSVV
3660 3670 3680 3690 3700
STQRKRAVLS CFRQASLHSL PRHRAINIFI RSYYELWLQD ENVGQEVMIE
3710 3720 3730 3740 3750
DLTQSFEDSE LKKKDGEEEE SKPDPLTQLV TTFCRGAMTE RSGALQEDPL
3760 3770 3780 3790 3800
YMSYAEIIAK SCGEEEEEGE EEESGEGEEG GASIHEQEME KQKLLFNQAR
3810 3820 3830 3840 3850
LAKRGVAEMV LLHISACKGV PSEMVMKTLE LGISILRGGN FDIQMGMLNH
3860 3870 3880 3890 3900
LKEKKDVGFF TSIAGLMNSC SVLDLDAFER NTKAEGLGVG SEGAAGEKNM
3910 3920 3930 3940 3950
HDAEFTCALF RFIQLTCEGH NLEWQNYLRT QAGNTTTVNV VICTVDYLLR
3960 3970 3980 3990 4000
LQESIMDFYW HYSSKDLIDP AGKANFFKAI GVASQVFNTL TEVIQGPCTL
4010 4020 4030 4040 4050
NQQALAHSRL WDAVGGFLFL FSHMQDKLSK HSSQVDLLKE LLNLQKDMIT
4060 4070 4080 4090 4100
MMLSMLEGNV VNGTIGKQMV DTLVESASNV ELILKYFDMF LKLKDLTSSP
4110 4120 4130 4140 4150
SFQEIDINND GWVSPKDFKE KMEQQKSYTS EEIDFLLACC EVNHDGKVDY
4160 4170 4180 4190 4200
IGFIDRFHEP AKEIGFNLAV LLTNLSEHMP NEPRLARFLE TAGSVLNYFE
4210 4220 4230 4240 4250
PFLGRIEILG GSKRIERVYF EIKESNIEQW EKPQIKESKR AFFYSIVTEG
4260 4270 4280 4290 4300
GDKEKLEAFI NFCEDAIFEM QHASGLMAVE ESGGGGPTRA ASYSYMNVDD
4310 4320 4330 4340 4350
EDRGKDPIRR GYQSIKEGIA YGLSSLSPSN IKHKFAEMQQ MTIPELFIGF
4360 4370 4380 4390 4400
FRMIIYAFYY SGFGVAIIFK YIFGVLLSLM RGPIEEPAVL EIKEEEEKVG
4410 4420 4430 4440 4450
LSRVLPALPS SEEQNTQMQA FGLDITKEDN GQYKMAAHES PTTSQPSSAE
4460 4470 4480 4490 4500
GEGETTPEED GEHPETETME APLSLSDLLG GEQAKRAAQE KVEAQAAQQA
4510 4520 4530 4540 4550
VMQAIESESK QPVVTEPSAV SQINFGAYSH RAVSFLARNF YNLKYVALVL
4560 4570 4580 4590 4600
AFCINFMLLF YRVSTLGDDA EGSGSKGIPD ILEGSAEGSG AGSGESGEDD
4610 4620 4630 4640 4650
DPPELVHVDE DFYYMAHVMR LAAILHSVVS LAMLIAYYNL KVPLAIFKRE
4660 4670 4680 4690 4700
KEIARRLEFE GLYIAEQPED DDLKSHWDKL VISAKSFPVN YWDKFIKKKV
4710 4720 4730 4740 4750
RQKYSETYDF DSISNLLGME KTSFQQQESD EGRSFIYFII NIDWRYQIWK
4760 4770 4780 4790 4800
SGVTITDNSF LYSLWYFIFS ILGNFNNFFF AAHLLDVAVG FKTLRTILQS
4810 4820 4830 4840 4850
VTHNGKQLVL TVMLLTIVVY IYTVIAFNFF RKFYVQEEDE EVDKKCHDML
4860 4870 4880 4890 4900
TCFVFHLYKG VRAGGGIGDE IEPPDGDDYE VYRIMFDITF FFFVIVILLA
4910 4920 4930 4940 4950
IIQGLIIDAF GELRDQLESV KEDMESNCFI CGMGKEYFDK VPHGFDTHVQ
4960 4970 4980 4990 5000
QEHNLANYMF FLMHLINKPD TEYTGQETYV WNMYQQRCWD FFPVGDCFRK
5010
QYEEELGGGG G
Length:5,011
Mass (Da):567,660
Last modified:May 11, 2016 - v2
Checksum:iF5B066543746CAA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ971327 Genomic DNA Translation: EEZ99829.2

Genome annotation databases

EnsemblMetazoaiTC002610_001; TC002610_001; TC002610

Similar proteinsi

Entry informationi

Entry nameiD6WF72_TRICA
AccessioniPrimary (citable) accession number: D6WF72
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: May 11, 2016
Last modified: February 28, 2018
This is version 53 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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